Microbiome News and Research

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New Research Maps Gut Microbiome Impact on Liver Cancer Immunotherapy Resistance

Immune checkpoint blockade (ICB) has reshaped the treatment landscape for advanced hepatocellular carcinoma (HCC), offering new hope where few options existed.

3 Jul 2026

Research Links Bifidobacterium animalis Metabolites to Improved Anti-Tumor T Cell Immunity

Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond or eventually develop resistance. The tumor microenvironment and the gut microbiome are increasingly recognized as critical determinants of immunotherapy outcomes.

2 Jul 2026

Advanced Bioinformatics Models Reveal Bacterial Function in Colon Cancer Patients

Over the past two decades, high‑throughput sequencing has dramatically expanded our understanding of the gut microbiome's composition.

29 Jun 2026

Global Study Identifies Robust Gut Microbiome Signature in Colorectal Cancer

Researchers have long suspected that the gut microbiome – the community of bacteria and other microorganisms living in the intestine – is closely linked to colorectal cancer.

25 Jun 2026

New Research Identifies Gut Fungi as Markers for Food Allergies

Two new studies jointly published in Nature: The Clinical Microbiome reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric allergic diseases - and may be promising targets for new therapies.

24 Jun 2026

RNA-Based Barcoding Tool Tracks Virus-Host Interactions Inside Bacterial Communities

An interdisciplinary team of Rice University researchers has uncovered previously unknown relationships between bacteriophages - viruses that infect bacteria - and their bacterial hosts, offering a powerful new tool for next-generation microbiome engineering.

17 Jun 2026

Molecular Cell Study Explains Gut Microbiome Impact on Liver Genes

A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function like molecular "switches".

16 Jun 2026

Phage Surface Proteins Act as Molecular Anchors to Attach Cells

Bacteriophages, or phages, are viruses that infect bacteria and are not considered human pathogens. Yet researchers at the Translational Microbiology Laboratory of the Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, have shown that some gut phages can also physically interact with human cells.

13 Jun 2026

Study Reframes the Deep-Sea as a Unique "Evolutionary Engine"

The deep sea is a unique 'evolutionary engine' with one of the richest and most unexplored sources of genetic diversity on Earth, according to a major new study that has assessed its potential to transform biotechnology and DNA sequencing technologies.

11 Jun 2026

Zebrafish Provide New Insights Into Microbiome Dynamics

A new advance in animal husbandry involving a popular aquarium fish should speed the pace of discovery in laboratory studies of host-microbe interactions, researchers report.

2 Jun 2026

MRM Health Rewarded a € 2.6 M VLAIO Research Grant to Accelerate the Development of Novel Therapeutics that Redefine the Treatment of Immune-Mediated Inflammatory Diseases

MRM Health, a clinical-stage biopharmaceutical company developing therapeutics for immune-mediated diseases, which unlock the power of the microbiome to restore immune balance, today announced that it has been awarded a research grant of € 2.6M from Flanders Innovation and Entrepreneurship (VLAIO), a government organization with the goal to stimulate economic development in Flanders, Belgium.

29 May 2026

Genetically Engineered Gene Deletions Reveal Unexpected Links Between Ghrelin and Blood Glucose Stability

Hormones influence how we feel - happy, sad or hungry - and profoundly shape how our bodies function and respond to disease.

25 May 2026

Specialized Intative Cells Release Peptide Hormones to Rapidly Signal an Amino Acid Deficiency

Eating is not only about getting enough calories. Animals also need to choose the right nutrients. When the body lacks protein, it must seek essential amino acids - the protein building blocks that cannot be made internally and must come from food.

23 May 2026

High-Resolution Cryo-EM Imaging Reveals a Hidden Secondary Drug Binding Site on Bacterial Ribosomes

A new Nature Communications study, published May 19, redefines scientists' understanding of how a popular class of antibiotics work.

22 May 2026

How Minimal Medical Care Shifts Amazonian Villagers' Unique Gut Bacteria

Even minimal exposure to modern medicine can rapidly change the human microbiome. In a new study publishing May 20 in the Cell Press journal Cell Reports, researchers reveal that the gut microbes of remote Amazonian Indigenous communities began shifting toward patterns more commonly seen in urban, industrialized populations after only a few medical visits.

21 May 2026

Microbes Switch Functional States Without Genetic Mutations to Withstand Stress

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have discovered that many gut bacteria use a flexible survival strategy to withstand disruptions such as antibiotics and diet changes.

20 May 2026

New Analysis Uncovers Evolutionary Adaptations Within Human Gut Bacteria

The human gut harbors a complex ecosystem of trillions of microorganisms (the microbiome), which influences digestion, the immune system and metabolism.

8 May 2026

How Genetic Bonuses Help Gut Bacteria Adapt to Industrialization

Billions of microorganisms-primarily bacteria, viruses, and fungi-colonize our gut. This complex community is known as the microbiome.

7 May 2026

MRM Health’s Lead Candidate MH002 Granted Fast Track Designation by U.S. FDA for the Treatment of Mild-to-Moderate Ulcerative Colitis

MRM Health, a clinical-stage biopharmaceutical company developing therapeutics for immune-mediated diseases, which unlock the power of the microbiome to restore immune balance, today announced that MH002, the Company’s lead rationally designed Live Biotherapeutic Product (LBP) candidate, has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for the treatment of mild-to-moderate ulcerative colitis (UC).

From MRM Health NV 4 May 2026

Genomic Tool TRACS Improves Tracking of Microbial Transmission Patterns

The research, published today (24 April) in Nature Microbiology, describes how the new tool, called TRAnsmision Clustering of Strains (TRACS), uses genomics to distinguish between closely related bacterial strains.

4 May 2026

Microbiome News and Research

New Research Maps Gut Microbiome Impact on Liver Cancer Immunotherapy Resistance

Research Links Bifidobacterium animalis Metabolites to Improved Anti-Tumor T Cell Immunity

Advanced Bioinformatics Models Reveal Bacterial Function in Colon Cancer Patients

Global Study Identifies Robust Gut Microbiome Signature in Colorectal Cancer

New Research Identifies Gut Fungi as Markers for Food Allergies

RNA-Based Barcoding Tool Tracks Virus-Host Interactions Inside Bacterial Communities

Molecular Cell Study Explains Gut Microbiome Impact on Liver Genes

Phage Surface Proteins Act as Molecular Anchors to Attach Cells

Study Reframes the Deep-Sea as a Unique "Evolutionary Engine"

Zebrafish Provide New Insights Into Microbiome Dynamics

MRM Health Rewarded a € 2.6 M VLAIO Research Grant to Accelerate the Development of Novel Therapeutics that Redefine the Treatment of Immune-Mediated Inflammatory Diseases

Genetically Engineered Gene Deletions Reveal Unexpected Links Between Ghrelin and Blood Glucose Stability

Specialized Intative Cells Release Peptide Hormones to Rapidly Signal an Amino Acid Deficiency

High-Resolution Cryo-EM Imaging Reveals a Hidden Secondary Drug Binding Site on Bacterial Ribosomes

How Minimal Medical Care Shifts Amazonian Villagers' Unique Gut Bacteria

Microbes Switch Functional States Without Genetic Mutations to Withstand Stress

New Analysis Uncovers Evolutionary Adaptations Within Human Gut Bacteria

How Genetic Bonuses Help Gut Bacteria Adapt to Industrialization

MRM Health’s Lead Candidate MH002 Granted Fast Track Designation by U.S. FDA for the Treatment of Mild-to-Moderate Ulcerative Colitis

Genomic Tool TRACS Improves Tracking of Microbial Transmission Patterns

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