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Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

Zebrafish Use Integrated Visual Signals to Move Up and Down in the Ocean

Using zebrafish, researchers from Osaka Metropolitan University (OMU) have identified the tegmentum region in the fish midbrain as the area where light input from both the fish's eyes and the pineal organ-the 'third eye'-is integrated.

31 Mar 2026

Study Reveals How Distributed Networks Support Complex Behavior

Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated networks. But scientists have had limited tools for selectively turning these specific connections "on" or "off" in animal models that most closely resemble the human brain.

31 Mar 2026

New Neural Organoid System Enables Scalable Brain Network Studies

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

30 Mar 2026

Fusion Protein Rewires Brain Development to Trigger Pediatric Cancer

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and collaborating institutions reveal in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor.

28 Mar 2026

Where Digital Holographic Microscopy Complements Fluorescence Microscopy

Integrating Digital Holographic Microscopy with fluorescence techniques enhances live-cell imaging, preserving cellular integrity and improving assay accuracy.

From Park Systems 25 Mar 2026

How Toxic Protein Spreads in Huntington’s Disease

Huntington's disease is a debilitating brain disorder that gradually robs people of mobility, memory, and personality.

23 Mar 2026

Comprehensive Brain Atlas Maps Epigenetic Changes During Aging

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

13 Mar 2026

Newly Discovered Neurons Respond to Complex Spatial Frequencies

The visual cortex is the part of the brain that enables visual perception. In this area millions of nerve cells, called neurons, process stimuli from the outside world.

11 Mar 2026

Specialized Tanycyte Brain Cells Found to Play Key Role in Tau Clearance

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

6 Mar 2026

DNA Changes in Alzheimer’s That May Drive Disease Progression

In a study published in Nature Communications, Mayo Clinic researchers discovered particular DNA-level abnormalities in the brains of Alzheimer's patients.

4 Mar 2026

Decoding the Molecular Machinery of Vesicle Transport

Since the 1940s, scientists have known that cells form tiny carriers called vesicles that move molecules among cellular compartments and to other cells.

2 Mar 2026

AI Tools Track and Identify Neurons in Moving Animals

Understanding the connection between behavior and brain cell activity is a major goal of neuroscience.

26 Feb 2026

Scientists Map Millions of Oligodendrocytes Across Mouse Brains

Johns Hopkins scientists say they have used 3D imaging, special microscopes and artificial intelligence (AI) programs to construct new maps of mouse brains showing a precise location of more than 10 million cells called oligodendrocytes.

24 Feb 2026

Unlocking the Fear Circuitry of the Brain

Consider a star-shaped cell in the brain, extending its spindly arms to cradle the neurons surrounding it. That is an astrocyte, and for a long time, scientists assumed its role was to care for the brain, gluing neurons together and preserving neural circuits.

23 Feb 2026