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Disrupted Honeycomb Cellular Patterns in the Early Brain May Drive Cancer and Birth Defects

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have dire consequences for developing brain cells. The findings offer important new insights into cancer and developmental disorders, helping explain how the body tries to protect itself and what happens when it can't.

21 May 2026

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve responses to immunotherapy.

20 May 2026

Stimulating Early Brain Circuits Partially Restores Vocal Defects Caused by Genetic Mutations

Communication begins long before children learn to speak. Researchers at National Yang Ming Chiao Tung University (NYCU) in Taiwan have now uncovered how early brain activity helps build developing communication circuits via regulating FOXP2/Foxp2, a gene linked to human speech and communication disorders.

20 May 2026

Researchers Compare Embryonic and Adult Mouse Brain Targets to Map Memory Networks

A peer-reviewed invited review published today in Genomic Psychiatry argues that the adult brain, when it learns and remembers and rewires, is not inventing something new.

20 May 2026

Advanced Genomic Techniques Map Cellular Changes During Brain Aging

While much is mysterious about the aging process, change over time remains its cornerstone. The biological shifts that accompany aging seemingly occur in many cells in the body.

18 May 2026

Protein Adgrl2 Regulates Brain Synapses and Blood Vessel Integrity

The communication network in the developing brain builds when neurons partner up to form contact points called synapses, allowing signals to pass form one cell to another.

28 Apr 2026

Ancient Genetic Sequences Found to Drive Human Language Abilities

In a first-of-its-kind finding, researchers at University of Iowa Health Care discovered that specific genetic sequences have an outsized impact on humans' language abilities and that these sequences evolved before humans and Neanderthals diverged.

23 Apr 2026

Kinesin Motor Protein Variations Control Cargo Specificity in Neuronal Transport

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations.

13 Apr 2026

CU Boulder Study Shows Genetic Link Between Mental and Physical Illness

For centuries, mental illness and physical disease have been viewed as two distinct categories, each with its own field of study, its own doctors, and its own menu of treatments.

10 Apr 2026

Molecular Switch AHR Limits Neuron Regeneration and Axon Repair

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

3 Apr 2026

Neural Circuit Controls Aggression Intensity in Stressed Mice

For many animals, aggression is essential for territorial defense. However, excessive aggression increases the risk of serious injury.

3 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

Zebrafish Use Integrated Visual Signals to Move Up and Down in the Ocean

Using zebrafish, researchers from Osaka Metropolitan University (OMU) have identified the tegmentum region in the fish midbrain as the area where light input from both the fish's eyes and the pineal organ-the 'third eye'-is integrated.

31 Mar 2026

Study Reveals How Distributed Networks Support Complex Behavior

Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated networks. But scientists have had limited tools for selectively turning these specific connections "on" or "off" in animal models that most closely resemble the human brain.

31 Mar 2026

New Neural Organoid System Enables Scalable Brain Network Studies

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

30 Mar 2026

Fusion Protein Rewires Brain Development to Trigger Pediatric Cancer

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and collaborating institutions reveal in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor.

28 Mar 2026

How Toxic Protein Spreads in Huntington’s Disease

Huntington's disease is a debilitating brain disorder that gradually robs people of mobility, memory, and personality.

23 Mar 2026

Comprehensive Brain Atlas Maps Epigenetic Changes During Aging

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

13 Mar 2026

Newly Discovered Neurons Respond to Complex Spatial Frequencies

The visual cortex is the part of the brain that enables visual perception. In this area millions of nerve cells, called neurons, process stimuli from the outside world.

11 Mar 2026

Specialized Tanycyte Brain Cells Found to Play Key Role in Tau Clearance

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

6 Mar 2026