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Distinct Neural Patterns Reveal How Mice Navigate Ambiguous Landmarks

When navigating a place that we're only somewhat familiar with, we often rely on unique landmarks to help make our way.

9 Jun 2025

UC Davis Study Links Specific microRNAs to Mental and Neurological Disorders

A study in Nature Aging from researchers at the UC Davis School of Medicine has identified specific microRNAs - non-coding RNAs that regulate gene expression within cells - that likely contribute to bipolar disorder, depression, schizophrenia, post-traumatic stress disorder (PTSD) and Parkinson's disease.

5 Jun 2025

Novel RNAs from Jumping Genes Produce Reverse Transcriptase Activity in Aging Neurons

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

Unlocking the Secrets of Synaptic Transmission

The reconstructed vesicle cycle model provides critical insights into synaptic transmission, advancing neuroscience and potential therapeutic applications.

30 May 2025

Study Reveals How APOE Isoforms Impact Brain Microglia

A study reveals how APOE isoforms influence microglial activity in Alzheimer's, highlighting the need for targeted interventions based on genetic risk factors.

28 May 2025

Microscopy Study Uncovers Dynamic Brain Remodeling During Hormonal Cycles

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles.

14 May 2025

How RNA-Binding Proteins and Circular RNAs Shape Tumor Biology

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

13 May 2025

Precision Mitochondrial DNA Editing Emerges as a Breakthrough in Neurological Care

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

13 May 2025

Estrogen Related Receptors Identified as Key to Muscle Energy Restoration

A new Salk Institute study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue.

13 May 2025

Same Gene Mutations Can Require Different Treatments in Autism and Schizophrenia

For patients with disorders such as autism and schizophrenia, mutations in the same gene could require different treatments, according to new research from Yale School of Medicine (YSM).

6 May 2025

Key Regulators of Mutant Huntingtin Protein in Neuronal Transport

Ten years ago, researchers from the University at Buffalo provided some insight into a long-standing neuroscience conundrum: How precisely does Huntington's disease result from a mutation in the huntingtin protein (HTT)?

6 May 2025

New Neural Circuit Discovery Explains Precision Steering in Fruit Flies

When a fruit fly is navigating straight forward at high speed, why does it know that it's not straying off course? Because as long as the fly moves directly forward, the visual scene shifts from front to back in a near-perfect mirror image across both retinas – generating, in other words, a symmetrical visual motion pattern.

2 May 2025

Study Reveals Shared Genetic Basis for Autism Spectrum Disorder and DM1

Researchers from the University of Las Vegas Nevada (UNLV) and The Hospital for Sick Children (SickKids) have discovered a genetic connection between autism spectrum disorder (ASD) and myotonic dystrophy type 1 (DM1), a rare genetic disorder.

23 Apr 2025

Breakthrough Ultrasound Technique Reveals Living Cells in 3D

While medical centers use ultrasound daily, so far this technology is not capable of observing body tissues at the scale of cells.

4 Apr 2025

Scientists Capture How Glutamate Opens Neuron Signaling Channels

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter.

29 Mar 2025

MitoBrainMap Unlocks Secrets of Brain Energy Distribution

Everything the brain does-from storing memories to interpreting sights to regulating emotions-requires energy, all produced by cellular organelles called mitochondria.

28 Mar 2025

Scientists Identify Crucial Mechanism for Maintaining Neuronal Identity in the Brain

A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with researchers from Columbia University (New York, USA), has identified a mechanism that regulates the production of two different proteins from the same gene.

24 Mar 2025

Dendritic Spine Clusters Physically Link Memories Formed Close in Time

According to a recent study, the reason why memories from the same day seem connected while events from weeks apart feel separate is as follows: Human brains use dendrites, which are spiny extensions of neurons, rather than the cell bodies to physically connect memories that happen in close succession.

24 Mar 2025

Scientists Reveal Brain Activity Dynamics During Male Sexual Behavior

To uncover what drives sexual behavior in animals, researchers studied the brain activity of male mice throughout the series of actions involved in sex leading up to ejaculation.

20 Mar 2025

Brain Research Offers Fresh Insights into the Nature Versus Nurture Debate

Riddle me this: how can it be that reading these words activates nearly identical word-sensitive patches of the brain's visual system in you and nearly every other reader of this story? And that a different set of face-sensitive visual regions-again in almost identical positions in each reader's brain-would activate to process the faces of the researchers, should you meet them?

18 Mar 2025