Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Developing GoT-Multi to Track Cancer Evolution and Treatment Resistance

A novel tool created by researchers at Weill Cornell Medicine and the University of Adelaide has improved the capacity to monitor multiple gene mutations while concurrently recording gene activity in individual cancer cells.

13 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025

Studies Uncover PAR2 Receptor’s Role in Gut Inflammation and Pain

Abdominal pain is common in a variety of digestive diseases, including inflammatory bowel disease and irritable bowel syndrome.

8 Oct 2025

How GBA Mutations Drive Cognitive Decline in Parkinson's Disease

Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain.

3 Oct 2025

Koala Retrovirus Load Stays Stable And Signals Higher Risk Of Chlamydia Infection

Findings show high koala retrovirus loads correlate with Chlamydia pecorum infection, emphasizing the need for further research on viral-host interactions.

1 Oct 2025

RyR1-Mediated CICR Plays Minimal Role in Normal Skeletal Muscle Contraction

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

26 Sep 2025

Breakthrough in Treating Age-Related Macular Degeneration with Retinal Stem Cells

In the United States, age-related macular degeneration is a leading cause of irreversible vision loss in people who are 60 and older.

24 Sep 2025

Metastatic Lung Cancer Cells Cozy Up to Neurons and Form Synapses

Small cell lung cancer cells that metastasize to the brain cozy up to neurons and form working electrical connections, called synapses, according to an upcoming study led by Stanford Medicine researchers.

11 Sep 2025

New Computational Tool Enhances Cancer Tissue Analysis for Personalized Treatment

Scientists at the Icahn School of Medicine at Mount Sinai have developed a powerful new computational tool that could transform how cancer tissues are analyzed and help pave the way for more personalized treatments.

27 Aug 2025

Mapping Kidney Cells Opens Path to Precision Medicine

A research team led by Indiana University School of Medicine physician scientists has made significant progress in mapping kidney cells that may one day allow for more accurate disease diagnosis.

22 Aug 2025

Epigenetic Noise Enables Cells to Shift Identity and Influence Immunity

All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on.

21 Aug 2025

New Technology Maps Over 140 Proteins Across Human Tissues

Each organ in the human body contains different types of cells arranged in specific ways.

20 Aug 2025

Feline Dementia May Explain Synapse Loss in Alzheimers

The study uncovers amyloid-beta's role in glial-mediated synapse loss in feline cognitive dysfunction, enhancing understanding of Alzheimer's disease.

20 Aug 2025

Missing Microexons Disrupt Synapse-Related Proteins in Pediatric Glioma

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

19 Aug 2025

New Enzyme Technology Illuminates Hidden Sugar Patterns on Cells

Sugars known as glycans form dense envelopes around cells. But they're often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are lacking.

18 Aug 2025

EVIDENT to Acquire Pramana, Inc.

Evident announces a definitive agreement to acquire Pramana, Inc., a leading manufacturer of digital pathology solutions.

From EVIDENT 14 Aug 2025

Microglia Replacement Therapy Offers Hope for Genetic Disorders Affecting the Brain

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

7 Aug 2025

Study Uncovers Genetic Roots of Stuttering

The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk.

29 Jul 2025

Gut Bacteria Adapt to Local Diets Offering Hope for Personalized Probiotics

Probiotics are emerging tools used by neonatal intensive care units to promote healthy outcomes and prevent intestinal diseases such as necrotizing enterocolitis.

18 Jul 2025

Microglia Replacement Halts Progression of Fatal Neurological Disease in Mice and Humans

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an average age of onset of 43 years and an average life expectancy of only 3 to 5 years after symptoms begin.

11 Jul 2025