Research News and Research

RSS

Mapping the Four Dimensional Organization of the Human Genome

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

Study Challenges Long-Held Assumptions About Mendelian Retinal Disorders

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

New vCATCH Method Maps Drug Binding Across Every Cell in the Body

When you take a drug, where in your body does it actually go? For most medications, scientists can make only educated guesses about the answer to this question.

23 Dec 2025

Simple Vibration Platform Enables Uniform Biomolecular Condensate Formation

A research group led by Professor Hiroaki SUZUKI and Takeshi HAYAKAWA from the Faculty of Science and Engineering at Chuo University, graduate student Zhitai HUANG, graduate students Kanji KANEKO (at the time) and Ryotaro YONEYAMA (at the time), together with Specially Appointed Assistant Professor Tomoya MARUYAMA from the Research Center for Autonomous Systems Materialogy (ASMat), Institute of Integrated Research (IIR), Institute of Science Tokyo, and Professor Masahiro TAKINOUE from the Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo, has developed a novel and highly accessible technology for producing uniform Biomolecular Condensates using a simple, low-cost vibration platform.

23 Dec 2025

Passive Adaptation Balances Protein Synthesis and Degradation in Cells

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but cannot simply accumulate inside the cell forever.

23 Dec 2025

Calcium Signaling Suppresses Lignin Accumulation in Pear Stone Cells

Stone cells arise from lignified secondary cell walls and cause a gritty texture, reduced sweetness, and poor flavor in many pear cultivars.

23 Dec 2025

Protein MCL1 Emerges as a Central Regulator of Cancer Metabolism

The researchers have succeeded in tracing two classic hallmarks of cancer – the evasion of apoptosis (a form of programmed cell death) and the dysregulation of energy metabolism – back to a common molecular mechanism.

23 Dec 2025

Foreign RsMYB28 Allele Boosts Glucosinolate Accumulation in Rapeseed

These bioactive compounds, found primarily in Brassicaceae plants, play crucial roles in plant defense, contribute to distinctive food flavors, and have potential health benefits, including cancer prevention.

23 Dec 2025

Wasatch Biolabs Announces Co-Marketing Agreement with Agilent to Advance Native-Read Targeted Sequencing

Wasatch BioLabs (WBL), a leader in native, long-read sequencing and epigenomic analysis, today announced a co-marketing agreement with Agilent Technologies to support the adoption of its Direct Targeted Methylation Sequencing (dTMS) platform.

22 Dec 2025

Researchers Map Gene Activation in Lethal Fungal Outbreaks

Scientists have discovered a genetic process which could unlock new ways to treat mysterious and deadly fungal infection which has shut down multiple hospital intensive care units.

22 Dec 2025

Machine Learning Models Identify Early Metabolic Shifts

Acute systemic inflammation has long been suspected to trigger harmful processes within the brain, contributing to neurodegenerative disorders such as Alzheimer's and Parkinson's disease. A new study published online in the Journal of Proteome Research on November 30, 2025, led by Professor Kei Zaitsu from the Faculty of Biology-Oriented Science and Technology, Kindai University, Japan, now provides compelling evidence that such inflammation causes region-specific metabolic disruption, identifying biochemical pathways that fail during the early stages of neuroinflammation.

22 Dec 2025

New Rat Study Reveals How Genetic Traits Ripple Through Social Microbiomes

The gut microbiome - made up of trillions of microbes in the digestive tract - is vital for digestion and overall health. Diet and medication shape these microbial ecosystems, but the contribution of genetics has been more difficult to ascertain.

22 Dec 2025

Study Identifies Protein Target to Overcome Drug Resistance in NSCLC

Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States.

22 Dec 2025

Unveiling the Secrets of Microbial Life on Fresh Lava

Life has a remarkable ability to recover, even in the aftermath of devastating occurrences such as forest fires or volcanic eruptions.

19 Dec 2025

Condensates Introduce a New Paradigm in Cellular Bioelectricity

Many biological processes are regulated by electricity-from nerve impulses to heartbeats to the movement of molecules in and out of cells.

19 Dec 2025

Study Reveals Glucose-Driven Mitochondrial Migration in Beta Cells

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear.

19 Dec 2025

A Global Catalog of Human Pluripotent Stem Cell Lines for Clinical Use

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental pipelines.

19 Dec 2025

New Method Enables Direct Freezing of iPS Cells in Culture Dishes

With a Kobe University-developed procedure, induced pluripotent stem cells can now be frozen directly in their dishes without losing their viability or undifferentiated state after thawing.

19 Dec 2025

Elusive Kinase State Explains How Cells Achieve Efficient Signaling

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its target, without needing to release

19 Dec 2025

Researchers Uncover Gene Control Elements Tied to Alzheimer’s Disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.

19 Dec 2025