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Rentschler Biopharma and Coriolis Pharma Announce Strategic Collaboration for Integrated Biopharma Solutions

Rentschler Biopharma, a leading global contract development and manufacturing organization (CDMO) for biopharmaceuticals, and Coriolis Pharma, a globally operating contract research and development organization (CRDO) and a leader in formulation research and development for biopharmaceuticals, today announced a strategic collaboration.

2 Dec 2025

Light-Activated AR3 Triggers Alkalinity-Driven Apoptosis in Cancer Cells

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression.

2 Dec 2025

Harnessing Triploid Loquat to Unlock Aneuploid Diversity for Advanced Breeding

Triploid plants are widely valued in horticulture for desirable traits such as seedlessness, yield improvement, and stress resilience.

2 Dec 2025

New Label-Free Breakthrough for Studying Bacterial Shape Diversity

Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean has remained a major challenge, especially for species that can't be grown in the lab.

2 Dec 2025

Decoding the Interaction Between SV2A Protein and Anti-Epileptic Drugs

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators established for the first time how certain drugs used to treat epilepsy affect their target.

2 Dec 2025

Unraveling How GFAP Mutations Disrupt Mitochondria in Alexander Disease

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare.

2 Dec 2025

Ambiguous Stop Codons Expand the Genetic Code in Archaea

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that's added to a chain of amino acids to make a protein.

2 Dec 2025

Study Uncovers How Polyploid Plants Harness Transposons for Evolutionary Innovation

Polyploidization, the combination and duplication of genomes, is a major driver of plant evolution and diversification. Yet this process causes "genome shock," leading to rapid activation of transposable elements (TEs).

2 Dec 2025

How Singing Mice Reveal the Roots of Vocal Communication

All mice squeak, but only some sing. Scotinomys teguina, aka Alston's singing mice, hail from the cloud forests of Costa Rica. More than 2,000 miles north, Cold Spring Harbor Laboratory (CSHL) neuroscientists study these musically gifted mammals to better understand the evolutionary origins of vocal communication.

2 Dec 2025

New Insight Into Light-Guided Growth of Bristleworm Eyes

A new study, led by the University of Vienna and the Alfred Wegener Institute in Bremerhaven, shows how the eyes of adult marine bristleworms continue to grow throughout life – driven by a ring of neural stem cells reminiscent of vertebrate eyes.

2 Dec 2025

CRISPR Technologies Transform On-Site Detection of Animal Pathogens

The rapid spread of animal diseases and pathogen evolution have long posed significant threats to the healthy development of animal husbandry.

28 Nov 2025

Capturing a Self-Splicing Ribozyme in Motion

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure.

28 Nov 2025

Real-Time Visualization Reveals the Transcriptional Gearbox

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins.

28 Nov 2025

Bird flu withstands human fever

Avian influenza viruses pose a specific risk to people, as they can multiply at temperatures exceeding a normal fever, which is a defense mechanism used by the body to halt viruses, according to new research conducted by Cambridge and Glasgow universities.

28 Nov 2025

New Regulatory Pathway Enhances Key Aroma Compound in Wine Grapes

β-Damascenone is a key norisoprenoid compound responsible for characteristic floral and fruity aromas in grapes and wines, particularly those from non-aromatic varieties such as Cabernet Sauvignon and Merlot.

27 Nov 2025

Study Identifies Adipogenin as Crucial Driver of Lipid Droplet Formation

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

27 Nov 2025

UBQLN2 Liquid Droplets Found to Catalyze Early α-Synuclein Aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease. α-synuclein (α-syn), a misfolded protein, aggregates and forms fibrils, which leads to the formation of LBs.

27 Nov 2025