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Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

Viral Metagenomics Uncovers Distinct Replication Machinery in Plateau Wetland Soils

Wetlands are well known for filtering water, storing carbon, and supporting biodiversity. Yet much of their microbial genetic diversity remains unexplored, particularly in high-altitude ecosystems.

26 Sep 2026

Neutrophil Activation by NMU Blocks Cytotoxic T Cell Tumor Infiltration

A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

26 Sep 2026

Researchers Engineer Synthetic Plant Receptors to Supercharge Crop Immunity

Nanyang Technological University, Singapore (NTU Singapore) scientists have developed a way to "supercharge" a plant's natural immune response.

26 Sep 2026

Individual Neurons Display Trial-to-Trial Firing Rate Variability Under Identical Visual Stimulation

Our brains internally represent the outside world through the coordinated activity of billions of neurons.

25 Sep 2026

Chronic Inflammation Linked to Heart Changes and Risks

Chronic inflammation, indicated by GlycA levels, has been linked to heart changes and increased cardiovascular risk, highlighting genetic and environmental interactions.

25 Sep 2026

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously. The findings, published in "Nature Communications," may explain a mechanism behind serious muscle diseases.

25 Sep 2026

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

Gut microbiota influences multiple aspects of host physiology, including metabolic and immune functions. Many metabolites produced by gut bacteria can cross the intestinal epithelium (which the bacteria may not be able to cross) and enter host tissues, providing a pathway through which microbial activity can influence host physiology.

25 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Type I Interferon Pathway Identified as Crucial Innate Viral Defense

Tick populations are expanding across the U.S., driving an increase in tick-borne diseases. Among them is Powassan virus, a rare but increasingly reported infection that can cause severe brain inflammation and lasting neurological complications.

25 Sep 2026

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart. Blocking the receptors together produced a much stronger antifibrotic effect than blocking them one at a time.

25 Sep 2026

Cancer-Associated Fibroblasts Construct Physical Barriers Limiting Antitumor T Cell Infiltration

Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown pathway that prostate tumors leverage to suppress the immune system by reshaping the tumor microenvironment to resist treatment.

25 Sep 2026

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

A world-first test developed by researchers at the Garvan Institute of Medical Research has identified the genetic cause of inherited muscle disease in people who remained without answers after years, sometimes decades, of standard testing.

25 Sep 2026

Hotter Temperatures Cause Hidden Cellular Ageing in Wild Birds

Climate change is causing hidden, cumulative cellular damage in wild birds, according to new research led by Monash University.

24 Sep 2026

Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

24 Sep 2026

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

Cysteine is one of the main building blocks that cells use to make proteins. But this amino acid is a double-edged sword–too much cysteine is toxic to the cell.

24 Sep 2026

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

A microscopic worm that has no kidneys is helping Rutgers scientists understand a genetic change suspected of causing a serious inherited kidney disease.

24 Sep 2026

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues have discovered that a type of rogue DNA found in aggressive cancers has a hidden structural weakness - and that blocking a single repair protein can cause it to fall apart, suggesting a new therapeutic opportunity.

24 Sep 2026

Trans-spliceosome Architecture Maps Evolutionary Divergence in Eukaryotic RNA Processing

A study conducted between the University of Liège and Rockefeller University reveals, with near-atomic precision, the three-dimensional structure and function of a gigantic molecular machine essential to the survival of trypanosomatid parasites, which cause serious diseases in humans, animals and plants.

24 Sep 2026

Research News and Research

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Viral Metagenomics Uncovers Distinct Replication Machinery in Plateau Wetland Soils

Neutrophil Activation by NMU Blocks Cytotoxic T Cell Tumor Infiltration

Researchers Engineer Synthetic Plant Receptors to Supercharge Crop Immunity

Individual Neurons Display Trial-to-Trial Firing Rate Variability Under Identical Visual Stimulation

Chronic Inflammation Linked to Heart Changes and Risks

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Type I Interferon Pathway Identified as Crucial Innate Viral Defense

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Cancer-Associated Fibroblasts Construct Physical Barriers Limiting Antitumor T Cell Infiltration

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

Hotter Temperatures Cause Hidden Cellular Ageing in Wild Birds

Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Trans-spliceosome Architecture Maps Evolutionary Divergence in Eukaryotic RNA Processing

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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