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New Research Maps Gut Microbiome Impact on Liver Cancer Immunotherapy Resistance

Immune checkpoint blockade (ICB) has reshaped the treatment landscape for advanced hepatocellular carcinoma (HCC), offering new hope where few options existed.

3 Jul 2026

Salk Study Identifies Brain Signaling Target to Prevent Cancer Cachexia

According to the Cleveland Clinic, a quarter of cancer deaths can be attributed to one source: cachexia. Cachexia is a syndrome that accompanies underlying chronic illness and causes unwanted muscle and fat loss, reducing quality of life and sometimes even limiting treatment options.

3 Jul 2026

Researchers Discover Genetic Markers Predicting Prostate Cancer Ferroptosis

A new study from researchers at The University of Texas MD Anderson Cancer Center has identified genetic factors that determine whether prostate cancers are susceptible to a type of cell death known as ferroptosis.

3 Jul 2026

Research Links Evolved Long Noncoding RNAs to Cancer Growth

In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have now uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become integrated into ancient cellular pathways that regulate cancer.

2 Jul 2026

Stem T Cells Replenish the Immune System During Chronic Infections and Diseases

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops. Where and how these killer troops are generated has been a mystery.

2 Jul 2026

Research Links Bifidobacterium animalis Metabolites to Improved Anti-Tumor T Cell Immunity

Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond or eventually develop resistance. The tumor microenvironment and the gut microbiome are increasingly recognized as critical determinants of immunotherapy outcomes.

2 Jul 2026

Cancer Cells Hijack Macrophage Metabolism to Create an Immunosuppressive Tumor Microenvironment

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment. However, instead of attacking cancer cells, they are typically co-opted to support tumor growth, metastasis, and therapeutic resistance.

2 Jul 2026

New SRV2 Viral Vector Boosts CAR-T Cell Production Efficiency

A Korean research team has developed a new viral vector technology that significantly improves the production efficiency of next-generation cell and gene therapies known as CAR immune cell therapies, which are designed to recognize and destroy cancer cells.

1 Jul 2026

Opposing Cellular States Collaborate Internally to Manage Vital Tissue Repair

Cellular senescence and stemness represent two biological entities with several opposing properties

30 Jun 2026

Mayo Clinic Scientists Discover Molecular Structures of Key Protein

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.

29 Jun 2026

Melatonin Enhances Random Skin Flap Viability by Suppressing Ferroptosis

Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries because they can be designed without depending on a single named blood vessel.

29 Jun 2026

Advanced Bioinformatics Models Reveal Bacterial Function in Colon Cancer Patients

Over the past two decades, high‑throughput sequencing has dramatically expanded our understanding of the gut microbiome's composition.

29 Jun 2026

Immune Pathway Breakthrough Reveals Critical Sex Differences in Female Glioblastoma

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory models, pinpointing an immune pathway that fuels tumor growth only in females.

24 Jun 2026

New Genetic Discovery Explains Why Colorectal Cancer Spreads so Quickly

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

23 Jun 2026

New Progenitor Cell Platform Offers Scalable Source for Immunotherapy

In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of the progenitor cells that give rise to macrophages.

22 Jun 2026

Targeting Iron Metabolism Offers a New Strategy to Kill Cancer Cells

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a key metabolic pathway that allows colorectal cancer cells to accumulate large quantities of iron. Blocking that pathway reduced iron levels and caused the cancer cells to die.

22 Jun 2026

Single-Cell Analysis Uncovers How Cancer Tumors Diversify and Resist Treatment

A comprehensive multi-cancer study from researchers at The University of Texas MD Anderson Cancer Center has revealed that cancer cells within tumors are genetically diverse, yet all carry the same core genetic changes that can be traced back to a common ancestral cell, providing a single-cell view of how tumors adapt, survive and diversify. Understanding this helps explain why some cancer cells manage to survive treatments, paving the way for more tailored diagnostic and therapeutic strategies.

22 Jun 2026