Tumor News and Research

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Study Uncovers Hidden Human "Dark Proteome" Members Across Protein Models

Hundreds of millions of proteins make up the known protein universe, but most remain largely unexplored. Inside the human body, thousands of these dark proteins remain mysteries. Scientists may know they exist, but not what they do or why they matter.

12 Sep 2026

New Insights Into How Giant-Nucleus Cells Promote Early-Stage Cancer Growth

Iron is an essential micronutrient, but excess iron can damage cells and increase cancer risk. While many cells die from iron-induced oxidative stress, a subset survives and may become cancerous. Previously, the identity of these surviving cells was unclear.

11 Sep 2026

Reprogramming Tumor Immune Microenvironment to Combat Aggressive Glioblastoma Brain Cancer

Mayo Clinic researchers have identified a potential new approach to treating glioblastoma that could help the immune system fight the aggressive brain cancer while improving the effectiveness of existing chemotherapy.

11 Sep 2026

Study Reveals Structural Roughness as Key Factor in Tumor Detachment Dynamics

In 2024, malignant tumors caused more than 21,300 deaths in Austria, 4.7% more than in 2014. Faced with a similarly pressing global challenge, scientists are striving to better understand what drives cancer cells to grow, spread, and invade healthy tissue.

10 Sep 2026

UCLA Breakthrough Generates Thousands of Allogeneic T-Cell Doses From Single Cord Blood Sample

T cell receptor, or TCR, therapy is a cancer treatment that genetically reprograms immune cells, called T cells, to hunt down cancer with precision.

9 Sep 2026

Advanced RNA Sequencing Separates Rare Regenerative Cells From Mature Tissue

Researchers at Weill Cornell Medicine and Hospital for Special Surgery have discovered the unspecialized stem cells that give rise to the body's tendons and ligaments, the tissues connecting muscles and bones.

8 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

Study Reveals Hidden Mutational Process in Colorectal Cancer

The discovery of SBS111 in colorectal cancer offers new perspectives on mutational processes and DNA repair, emphasizing its significance in tumor biology.

3 Sep 2026

UNC Researcher Wins Mathers Foundation Grant to Study T-Cell Metabolism

Jessica Thaxton, PhD, MsCR, associate professor in the Department of Cell Biology and Physiology at the UNC School of Medicine and co-leader of the Cancer Cell Biology Research Program at UNC Lineberger Comprehensive Cancer Center, has been awarded a prestigious $700,000 grant from the Mathers Foundation to support research into the role of the endoplasmic reticulum in T-cell metabolism and cancer development.

2 Sep 2026

Super-Resolution DNA Imaging Platform Links Chromatin Loosening to Tumor Progression

Scientists have engineered fluorescent molecules enabling the visualization of DNA organization within living cells with unparalleled resolution, and in fixed cells, nearly the width of the double helix itself.

31 Aug 2026

Moving Beyond DNA Sequencing Unlocks New Paths Managing Human Health

Scientists from Gladstone Institutes, UC San Francisco, and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding of how genetics control health and disease.

31 Aug 2026

Machine Learning Tool Uncovers Epigenome Patterns Without Predefined Labels

In a study recently published in Nature Communications, researchers from Berlin, Potsdam, and Jena present a new method for analyzing the epigenome, the genome's control system that determines which genes are switched on and off.

28 Aug 2026

OIST Scientists Uncover Fleeting Sugar Pairs Regulating Cell Division

Acting as an armor, a scaffold, and a communication platform in one, our cells' plasma membrane lies at the heart of many crucial cellular processes.

28 Aug 2026

Newly Found Fibroblasts Help Lung Tumors Evade Immune System

Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system.

28 Aug 2026

Colorectal Cancer and Nerve Damage: A Hidden Link Uncovered in Mice and Primates

Colorectal tumors trigger inflammatory nerve damage, suggesting cancer itself may be a risk factor for neuropathy in survivors, independent of treatments.

27 Aug 2026

Mutation Stalls Immature Brain Cell Maturation Leading to Aggressive Gliomas

Scientists at St. Jude Children's Research Hospital have shown that specific brain cells respond differently to the H3.3 K27M, a mutation in the histone H3.3 protein that drives many cases of diffuse midline glioma (DMG), depending on the cell's location in the developing brain.

27 Aug 2026

Engineering Stem-Cell-Derived Immune Cells to Teach T Cells to Fight Cancer

The human body contains vast numbers of T cells capable of seeking out and eliminating malignancies if they were properly activated. Currently, a group from UC San Francisco has developed a technique to achieve this by merging laboratory-cultivated immune cells with samples from a person's malignancy.

26 Aug 2026

Novel T-Cell Engineering Strategy Prevents Deadly Osteosarcoma Lung Metastasis

Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma.

26 Aug 2026

New Study Identifies FAM120A as Critical Protein in Tumor Establishment

Researchers investigating the role of progranulin in cancer progression have previously identified the signaling receptor EphA2 as critical in tumor establishment and potential target to enhance the effectiveness of chemotherapy.

26 Aug 2026

Study Redefines How Cancer Cells Enter Senescence

Stopping tumor growth is only half the battle. Rather than kill tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells will continue to release signals that reshape the tumor environment.

21 Aug 2026