Tumor News and Research

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High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

22 May 2026

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

Researchers with the James P. Allison Institute™ at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.

21 May 2026

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying people at higher risk of cancer or even, potentially stopping malignant transformation.

21 May 2026

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

Genetic Engineering Creates an Immune System Cloak to Extend Bacterial Drug Circulation

While previous research from Johns Hopkins University is successfully completing clinical trials, University of Rhode Island College of Pharmacy Assistant Professor Kaitlin Dailey is expanding on that work to more specifically target tumors that are difficult or impossible to access, especially those associated with pancreatic cancer-one of the deadliest types.

21 May 2026

Open-Chip Design Separates Fluid Resistance From Wall Confinement to Trace Cell Behavior

Most cancer studies focus on chemical signals or stiff tumor surroundings, but the stickiness of the fluid itself has received little attention. For glioblastoma, the invasion front is about eight times more viscous than the necrotic core, creating a rising resistance that migrating cells must overcome.

21 May 2026

Engineers Develop New mRNA Adjuvant That Dramatically Amplifies Cancer-Fighting T Cells

Engineers from the University of Houston, MIT and Harvard have developed a new mRNA-based strategy that dramatically amplifies the T-cell response to vaccines - an advance that could lead to far more powerful cancer vaccines and stronger protection against infectious diseases.

20 May 2026

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb, and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma.

20 May 2026

Copper-Free Click Reactions Allow Safe In Vivo Tracking of Tumors Inside the Body

Conventional cancer treatments like chemotherapy often struggle with poor targeting, leading to severe systemic toxicity and drug resistance. Diagnostic techniques, while improving, are frequently invasive and cannot monitor treatment responses in real time.

20 May 2026

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Researchers developed a 3D liver model that functions for a month, replicating inflammation and fibrosis, crucial for studying liver diseases and therapies.

19 May 2026

Dual-Action Protein Found to Fuel and Repair Cancer

According to a recent study, a protein best known for fueling cancer development also aids in the survival of damaged tumor cells by repairing their DNA, which might impact how certain cancers are treated.

18 May 2026

Glycan Biomarkers Enable Accurate Prediction of Biological Aging in Mice

A new study published in Engineering has established an absolute quantification strategy for immunoglobulin G (IgG) N-glycans linked to aging, providing a reliable method to assess biological age and explore anti-aging interventions.

15 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

Scientists Discover How DNA Damage Modulates the Tumor Microenvironment for Therapy

Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair.

14 May 2026

Restricted Interaction Peptides Change Shape to Lock Therapy Inside Solid Tumors

Medications are designed to treat diseased tissues while sparing healthy ones, often by attaching the drug to something that helps guide it directly to its target.

14 May 2026

Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly used therapies.

14 May 2026

Inherited Genetic Pathways Shape Individual Cancer Risk and Outcomes

Why do two people with the same cancer diagnosis-the same stage, the same cell type, and the same clinical profile-often have completely different outcomes? For decades, scientists have studied acquired mutations in cancer to find answers, but mutations alone explain only part of the story.

12 May 2026

Mechano-Chemo-Biological Coupling May Explain Complex Tissue Behaviors

Modern biology can now image forces, structures, and signals with remarkable precision, yet explaining how they work together remains difficult.

11 May 2026

Extra Chromosomes Trigger Cellular Changes Linked to Tumor Aggressiveness

One of the biggest challenges in cancer research is understanding why some tumor cells become especially aggressive, invasive and resistant to treatment.

11 May 2026

Tumor News and Research

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Genetic Engineering Creates an Immune System Cloak to Extend Bacterial Drug Circulation

Open-Chip Design Separates Fluid Resistance From Wall Confinement to Trace Cell Behavior

Engineers Develop New mRNA Adjuvant That Dramatically Amplifies Cancer-Fighting T Cells

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

Copper-Free Click Reactions Allow Safe In Vivo Tracking of Tumors Inside the Body

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Dual-Action Protein Found to Fuel and Repair Cancer

Glycan Biomarkers Enable Accurate Prediction of Biological Aging in Mice

Animals Adapt Rapidly Through Protein Networks, Not Genes

Scientists Discover How DNA Damage Modulates the Tumor Microenvironment for Therapy

Restricted Interaction Peptides Change Shape to Lock Therapy Inside Solid Tumors

Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Inherited Genetic Pathways Shape Individual Cancer Risk and Outcomes

Mechano-Chemo-Biological Coupling May Explain Complex Tissue Behaviors

Extra Chromosomes Trigger Cellular Changes Linked to Tumor Aggressiveness

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