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Tirzepatide Reduces Alcohol Drinking And Relapse In Preclinical Study

Tirzepatide alters brain reward signaling and reduces alcohol intake in rodents, indicating its potential as a therapeutic option for alcohol use disorder.

4 Mar 2026

Macrophages Offer a Safer Alternative to CAR-T Therapies with Lower Toxicity

A new study from researchers at Wake Forest University School of Medicine has identified a promising strategy to treat brain metastases, one of the most challenging and deadly complications of lung cancer.

3 Mar 2026

Structural Blueprint of Cellular Biomolecular Condensates Opens New Therapeutic Possibilities

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

26 Feb 2026

Engineering Bacteria for Targeted Cancer Destruction

A University of Waterloo-led research team is creating a unique cancer treatment technique that involves designing hungry bacteria to literally devour tumors from the inside out.

25 Feb 2026

Extracellular Matrix Sensing Enables Pancreatic Cancer Cells to Regulate Autophagy Levels

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.

17 Feb 2026

Tumor Environment Constrains Cellular Signal Carrying Vesicles

A new study may change the way scientists think about the distance traveled by tiny bubbles carrying signals between cells that are embedded in tissue.

12 Feb 2026

Single-cell atlas reveals how melanoma evades the immune system

Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key factors in melanoma progression.

11 Feb 2026

Cells Use Protein Partnership to Manage Oxidative Stress

Cornell researchers have discovered a new way cells regulate how they respond to stress, identifying an interaction between two proteins that helps keep a critical cellular recycling system in balance.

10 Feb 2026

Tool Enables Accurate Detection of Microbes in Cancer Genomes

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how they grow, evade immunity or respond to treatment.

10 Feb 2026

New Gene-Editing Strategy to Eliminate Aggressive Cancer Cells

The initiation and severity of cancer are associated with the atypical behavior of specific genes, referred to as oncogenes. The most recognized of these changes is mutation; however, it is not the sole alteration.

9 Feb 2026

New Genetic Rules Guide Killer T Cell Fate

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune cells-known as CD8 killer T cells-choose between becoming long-lasting, protective defenders or slipping into exhausted, dysfunctional states.

6 Feb 2026

Aged Neutrophils With CCL3 Drive Tumor Growth Across Cancers

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

Lightweight AI Model Reveals Rules Governing Gene Regulation

Gene regulation is far more predictable than previously believed, scientists conclude after developing deep learning model PARM.

5 Feb 2026

Ancestry-Specific Genetic Models Advance Breast Cancer Risk Assessment

Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among women of African ancestry.

4 Feb 2026

Gravity-Driven Microfluidic Platform Enhances Immune Cell-Tissue Co-Culture

Advanced in vitro models such as organ-on-chip systems aim to replicate human physiology more accurately than conventional cell cultures. However, most existing platforms struggle to incorporate circulating cells like immune cells or circulating tumor cells.

3 Feb 2026

Novel RNA Molecule Preserves Cell Structure, Impacts Cancer Survival

In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Texas A&M University Health Science Center (Texas A&M Health) identify a novel RNA molecule that plays a crucial role in preserving the integrity of a key cellular structure, nucleolus (a dense region of the cell containing a subset of crucial genetic material).

3 Feb 2026

Study Uncovers a Crucial Factor to Improve Treatment for Glioblastoma

A groundbreaking study from Brown University Health researchers has identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer.

2 Feb 2026

New Research Reveals RFC's Dynamic Partnership in DNA Synthesis

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its code and build new strands.

2 Feb 2026

Gut Microbial Metabolite Hippuric Acid Amplifies Immune Responses

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea, and other plant-based foods.

31 Jan 2026

Natural Molecular Brake Prevents Uncontrolled DNA Replication in Cells

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we would die.

29 Jan 2026