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Visualizing Immune Synapses in Three Dimensions Using Cryo-Expansion Microscopy

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells.

30 Apr 2026

Microbead Lasers Reveal Cellular Forces in Complex Tissue Environments

Researchers have developed tiny flexible lasers that can be used to measure forces inside living cells.

30 Apr 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

New Pipeline Sharpens Single-Cell Profiling of CAR Immune Therapies

CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies.

29 Apr 2026

Intermediate PRRX1 Levels Drive Breast Cancer Metastasis Risk

The study identifies PRRX1 as a critical factor in breast cancer metastasis, highlighting its potential as a biomarker for predicting aggressive disease.

29 Apr 2026

High Resolution Images Reveal DNA Repair Process in Key Protein

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers.

28 Apr 2026

Advances in Proteomics Accelerate Precision Oncology and Biomarker Discovery

A recent review shows that proteomics-driven multi-omics integration reveals tumor heterogeneity and functional regulatory networks beyond genomic information, facilitating the discovery of clinically relevant biomarkers and therapeutic targets.

28 Apr 2026

Stress Response in Polyploid Cells Fuels Cancer Progression

One of the biggest challenges in cancer research is understanding why some tumor cells become especially aggressive, invasive and resistant to treatment.

24 Apr 2026

New VIS-Fbs Technology Offers Sharper Images of Living Cellular Processes

Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals.

23 Apr 2026

New Method Predicts Cancer Patient Outcomes at Single-Cell Resolution

Oregon Health & Science University researchers have developed a first-of-its-kind method to predict cancer patient survival using advanced molecular data from individual cells.

22 Apr 2026

New Molecular Imaging Technology Illuminates Proteins Inside Living Cells

Fluorescent probes have transformed modern biology by allowing researchers to tag and visualize individual molecules in living cells, tissues, and animals.

22 Apr 2026

Brain Immune Cells Play Key Role in Glioblastoma Tumor Infiltration

Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond the main tumor.

22 Apr 2026

Sylvester Cancer Center Launches Cloud-Based Platform for Unified Genomic Data

Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, has developed a novel, cloud-based informatics platform that combines clinical and genomic data from multiple sources into one unified platform.

21 Apr 2026

New Data Demonstrates the Unique Scalability of Evaxion’s AI-Immunology™ Platform in Glioblastoma

Evaxion A/S (“Evaxion”), a clinical-stage TechBio company developing novel vaccines with its pioneering AI-Immunology™ platform, announces new data demonstrating the platform’s ability to also potentially develop vaccines for glioblastoma (brain cancer).

From Evaxion A/S 21 Apr 2026

Scientists Uncover the Molecular Fingerprints of mRNA Vaccine-Induced T Cells

The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel-prize–winning technology is being adapted to fight cancer, with mRNA vaccines in clinical trials for melanoma, small cell lung cancer and bladder cancer, among others, opening the door to new ways of preventing and treating the disease.

17 Apr 2026

Researchers Develop 3D Organoids that Reflect the Complexity of Brain Tumors

Efforts to identify and evaluate next-generation therapeutics for pediatric brain tumors are easily stymied by the quality and availability of laboratory models for research. To address this issue, scientists at St. Jude Children's Research Hospital developed patient-derived tumor organoids and tumor organoid xenografts that accurately reflect the biologic underpinnings of embryonal brain tumors.

16 Apr 2026

Identifying Somatic Driver Mutations in Thyroid Autoimmune Disease

According to recent studies, immune cell DNA mutations that eliminate the immune system's natural brakes may be the cause of autoimmune disorders.

15 Apr 2026

UTMB Researchers Develop AI Pipeline to Accelerate Pan-Alphavirus Vaccine Development

A team of scientists at The University of Texas Medical Branch (UTMB), led by Nikos Vasilakis, PhD, and Peter McCaffrey, MD, has developed a new computational pipeline that could dramatically accelerate the development of vaccines against a group of mosquito-borne viruses known as alphavirus.

11 Apr 2026

New Experimental System Mimics Low-Grade Pediatric Glioma in 3D

A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor of the central nervous system that often occurs in children.

10 Apr 2026