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Cancer invasion and migration can be suppressed by manipulating stiffness of cell membrane

A research collaboration has found that cancer invasion and migration in mice can be inhibited by controlling the stiffness of the cell membrane.

10 Nov 2021

Skin regeneration after an injury may be linked with motility of skin stem cells

Although sometimes hard to accept, with aging, many things in our bodies change. One of these is the ability of the skin to regenerate. Old skin is just not as good as young skin at healing wounds. However, the molecular and cellular mechanisms underlying this are largely unknown.

18 Oct 2021

Study outlines the advantages of organoids for basic research into coronaviruses

Scientists created an organoid biobank to investigate the genes that are vital for the spreading of a SARS-CoV-2 infection.

21 Sep 2021

Scientists discover how thousands of tiny anchors help the cells stay put and resist disruptions

Most of the cells in our bodies – be they bone, muscle or pancreas cells – are locked into the right place with the help of tiny anchors (called 'focal adhesions').

From The University of New South Wales (UNSW) 14 Sep 2021

Study identifies the role of lysosomes in the spread of Parkinson’s disease

In the past few decades, neurodegenerative diseases have turned into one of the top 10 worldwide causes of death.

26 Jul 2021

Study unravels the biomechanical, biophysical response of cancer cells to drugs

A new study reports the use of single-cell, force spectroscopy methods to probe biophysical and biomechanical kinetics of cancer cells.

21 Jul 2021

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Oncotarget published "Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy" which reported that by exploiting single-cell, force spectroscopy methods, the authors probed biophysical and biomechanical kinetics of brain, breast, prostate, and pancreatic cancer cells with standard chemotherapeutic drugs in normoxia and hypoxia over 12-24 hours.

20 Jul 2021

Protein's 'silent code' influences cell movement

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% of their amino acid sequence.

8 Jul 2021

Newly identified protein regulates the flow of materials in the Drosophila ovary

According to a research work performed by Northwestern Medicine and published in the Current Biology journal, a protein helps guide the flow of materials in the ovary of Drosophila fruit flies during the formation of egg cells.

17 Jun 2021

Newly identified protein helps tumors evade the immune system

Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

3 Jun 2021

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

Researchers study the mechanical properties of prostate cancer cells treated with anti-cancer drugs

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow.

28 May 2021

New probe allows real-time imaging of molecular orientations in live cells

Monitoring alignments of the building blocks of cells is important to understand how the cells are built. By collaborating with imaging scientists at the MBL, researchers from Japan have developed a new probe which they call POLArIS, allowing real-time imaging of molecular orientations in live cells.

17 May 2021

New atomic force microscopy enables faster, less-invasive imaging of biological samples

Kanazawa University researchers have reported a new approach of atomic force microscopy for imaging biological processes and specimens.

31 Mar 2021

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Using electron cryo-tomography, researchers have created the first high-resolution 3D image of the sarcomere.

25 Mar 2021

Study reveals new mechanism through which cells build “mini-muscles”

Research teams have revealed how the motor protein, called myosin, which is responsible for causing the contraction of skeletal muscles, also functions in non-muscle cells.

3 Mar 2021

New statistical study shows how pairs of cancer cells interact

One of the fundamental principles of biology is the fact that cells are motile and make contact with one another.

17 Feb 2021

Researchers discover new molecular mechanism that promotes cell migration

Research groups at the University of Helsinki and Institut Jacques Monod, Paris, discovered a new molecular mechanism that promotes cell migration. The discovery sheds light on the mechanisms that drive the uncontrolled movement of cancer cells and also revises the 'textbook view' of cell migration.

10 Feb 2021

New insights into the biology of chytrid fungus responsible for deadly skin infection

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

9 Feb 2021

New mathematical model captures forces involved in cell movement

Physicists have teamed up to find out the precise mechanisms that play a crucial role in cell motility.

19 Jan 2021