Actin News and Research

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SNAP-tag2 System Improves Protein Imaging with Faster, Brighter Labeling

SNAP-tag2 boosts live-cell imaging with faster labeling, brighter fluorescence, and better protein tracking across biological systems.

11 Jul 2025

Cell Adhesion Mechanisms Behind Endometriosis Spread

The study uncovers how ovarian ECM tropism influences endometriotic cell adhesion, paving the way for novel strategies to combat endometriosis effectively.

2 Jul 2025

Raman Spectroscopy Detects Early Cervical Changes During Pregnancy

Raman spectroscopy detects early biochemical changes in the cervix during pregnancy, revealing increased vascularity and reduced collagen within 6–8 weeks post-conception.

23 Jun 2025

Organotypic Model of the Human Gut Epithelium Demonstrates Genetic Determinants of Shigella Colonization

A study in Nature Genetics uses organotypic gut models to reveal genome-wide genetic determinants of Shigella colonization, spotlighting type III secretion system effectors as crucial for early infection.

20 Jun 2025

New Inherited Disorder Impairs DNA Repair and Raises Cancer Risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

18 Jun 2025

Study Shows Fibronectin Tension Loss Correlates With Breast Cancer Progression

Fibronectin fibers lose tension in invasive breast cancer, unlike in healthy or DCIS tissues, suggesting a mechanical marker for tumor progression.

16 Jun 2025

Study Explores Use of Laser-Patterned Diamonds in Stem Cell Applications

A study in Advanced NanoBiomed Research presents laser-graphitized diamond electrodes that support human mesenchymal stem cell adhesion, alignment, and proliferation, advancing bioelectronic applications.

10 Jun 2025

Myosin XI Helps Plants Absorb Boron Under Nutrient Stress

Boron, though required only in minimal amounts, is vital for plant development. It strengthens cell walls and supports the growth of roots and shoots.

9 Jun 2025

Three-Dimensionally Reconstructed Kidney Glomerulus Simulates Structural and Functional Characteristics In Vitro

A 3D engineered kidney glomerulus model replicates structural and mechanical features of the glomerular filtration barrier, enabling the study of podocyte-related diseases and drug screening with improved physiological relevance.

2 Jun 2025

Study Identifies SMARCB1 and MEOX2 Genes as Growth Regulators of Lung Cancers

A Cancer Gene Therapy study reveals that MEOX2 promotes lung cancer progression while SMARCB1 acts as a tumor suppressor, influencing EGFR expression and response to tyrosine kinase inhibitors.

30 May 2025

3D Printing Collagen Scaffolds with Perfusable Systems for Tissue Engineering

Scientists have developed high-resolution 3D-printed collagen scaffolds with internal perfusion systems, enabling complex, vascularized tissue models that support cell viability, growth, and insulin secretion

6 May 2025

Fluid Dynamics of Stentors Offers New Insight Into Evolution of Multicellular Life

Life emerged on Earth some 3.8 billion years ago. The "primordial soup theory" proposes that chemicals floating in pools of water, in the presence of sunlight and electrical discharge, spontaneously formed organic molecules.

1 Apr 2025

Unraveling the Evolutionary Link to Eukaryotic Cells

A decade ago, the existence of Asgard archaea was unknown. However, in 2015, researchers analyzing deep-sea sediments uncovered gene fragments that suggested the presence of a new, previously unidentified group of microbes.

24 Mar 2025

Gamma-Actin's Influence on Cell Rigidity and Junctional Proteins

Epithelial cells defend human skin and mucous membranes. Specialized structures known as “junctions” enable this “barrier” tissue to carry out its role. They control interactions between cells and maintain cell cohesion.

21 Mar 2025

Segmented Nerve Cords Enable Precision and Flexibility in Cephalopod Arms

Findings on cephalopod nerve cords highlight segmentation's role in sucker movement control, advancing knowledge of neural architectures in soft-bodied species.

24 Jan 2025

The Critical Role of TRiC in Brain Development and Function

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

29 Nov 2024

New Discovery Shows TAGLN2 Protein Boosts T Cell Immunity Against Tumors by Enhancing Lipid Metabolism

Findings indicate ovarian cancer disrupts CD8+ T cell metabolism through FABP5 and TAGLN2, suggesting new therapeutic targets for enhancing immune function.

1 Nov 2024

F-Actin Accumulation Impairs Brain Function in Aging Fruit Flies

Humans aren't the only ones who grow forgetful as they age -; fruit flies do, too. But because fruit flies have a lifespan of only about two months, they can be a useful model for understanding the cognitive decline that comes with aging.

29 Oct 2024

New Method for Identifying Kinase Inhibitors for Cancer Therapy

The most difficult subtype of breast cancer to treat is triple-negative breast cancer (TNBC). Over 20,000 cases of TNBC are reported each year in the United States alone.

10 Oct 2024

Engineering Tissue Domains with a Synthetic Biology Approach

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

9 Oct 2024