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Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

A genetic modification in the 'coat' of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers.

23 Nov 2020

Research sheds light on T cell abnormality in critically ill COVID-19 patients

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients.

23 Nov 2020

MMR vaccine may be protective against COVID-19, study shows

The measles-mumps-rubella (MMR) vaccine has been theorized to provide protection against COVID-19. In a new study published in mBio, an open-access journal of the American Society for Microbiology, researchers provide further proof of this by showing that mumps IgG titers, or levels of IgG antibody, are inversely correlated with severity in recovered COVID-19 patients previously vaccinated with the MMR II vaccine produced by Merck. MMR II contains the Edmonston strain of measles, the Jeryl Lynn (B-level) strain of mumps, and the Wistar RA 27/3 strain of rubella.

23 Nov 2020

Pairs of antibodies may be more effective at preventing and treating COVID-19

Pairs of antibodies may be more effective than single antibodies at preventing and treating COVID-19, according to a new study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University in New York.

20 Nov 2020

New method could more sensitively detect circulating tumor cells

Breast cancer is the most frequently diagnosed cancer in women, and metastasis from the breast to other areas of the body is the leading cause of death in these patients.

19 Nov 2020

Study shows immunological memory can prevent reinfection in COVID-19 survivors

Researchers were uncertain whether a survived SARS-CoV-2 infection results in immunological memory and thus can guard against a new infection, until now.

18 Nov 2020

Study detects changes in how diseased neurons sense and use oxygen

Scientists have devised a new method for isolating a kind of brain cell that is related to symptoms of Parkinson’s disease.

17 Nov 2020

Mutations in SARS-CoV-2 spike protein may improve monoclonal antibody resistance

A recent paper examines a mutation of the spike protein of SARS-CoV-2 that has been observed to have arisen independently twice.

10 Nov 2020

White blood cells can be trained to attack tumor cells

Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.

9 Nov 2020

Genetically edited form of herpes simplex virus outperforms key vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

9 Nov 2020

Highly automated device rapidly detects the presence of COVID-19

Throughout the pandemic, infectious disease experts and frontline medical workers have asked for a faster, cheaper and more reliable COVID-19 test.

6 Nov 2020

Researchers use new technology to design promising vaccine for COVID-19

A new nanoparticle vaccine candidate developed for the novel coronavirus creates virus-neutralizing antibodies in mice at levels that are 10 times higher than is observed in individuals, who have recovered from the COVID-19 disease.

4 Nov 2020

Human immune system may play a key role in shaping the microbiome composition

The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch.

30 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Myeloid cell can suppress the immune response to tumor cells

For a long time, researchers had believed that the brain reduces inflammation by protecting itself from an aggressive immune response.

28 Oct 2020

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus's distinctive spikes and induces critical pieces of those spikes to break off in the process.

28 Oct 2020