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New Vaccine Shows Promise in Combating MenB

Investigators from the Universities of Surrey and Oxford have declared that a vaccine candidate that can shield children from Meningococcal group B (MenB), which can cause meningitis, has advanced to clinical development.

19 Jul 2023

Mast Cells May Help Humans Avoid Harmful Antigens

Mast cells, which are part of the immune system, are still a puzzle. Mast cells function as a sensor that signifies the animals to avert antigens, including harmful allergens, and thus safeguard themselves from health-threatening inflammatory reactions, according to researchers at the German Cancer Research Center (DKFZ). The research was published in the journal Nature.

13 Jul 2023

AI-Aided Sensor Offers Hope for Early Detection of Neurodegenerative Diseases

By combining multiple advanced technologies into a single system, EPFL researchers have made a significant step forward in diagnosing neurodegenerative diseases (NDDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD).

13 Jul 2023

Unknown Membrane Proteins for Ovarian Cancer Diagnosis

Three previously undiscovered membrane proteins in ovarian cancer have been discovered by a study led by Nagoya University in Japan.

10 Jul 2023

Cryo-EM Reveals Structure of GABA Transporter

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

7 Jul 2023

Cell Fate Conversion Plays Crucial Role in Cancer Research

Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin and the Centre for Genomic Regulation (CRG) in Barcelona have discovered how cells speed changes to their identity known as “cell fate conversion.”

28 Jun 2023

Microglial Cells Serve as a Stable Viral Reservoir for Latent HIV

Human immunodeficiency virus-1 (HIV) introduces a copy of its DNA into human immune cells as part of its life cycle. Some of these newly infected immune cells can subsequently enter an inactive, latent state for an extended length of time, which is known as HIV latency.

19 Jun 2023

Breakthrough: Sequencing Functional Antibody Proteins Directly from Human Blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

Scientists Integrate Multiple Therapeutic Approaches to More Effectively Target Brain Metastatic Melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

1 Jun 2023

Using Synthetic Peptides in Next-Generation Inflammatory Disease Diagnostic Assays

Conditions like ulcerative colitis and Crohn's disease, which cause inflammation in the body, can be identified or tracked by measuring a protein called calprotectin.

29 May 2023

IgA Described as "Tuner" in Microbe Interaction Regulation

Throughout the world, IgA deficiency is considered to be the most common primary immune deficiency, but its presentation has continued to confuse researchers and physicians.

29 May 2023

Deep-Sequencing Identifies Over 10,000 Unique Genes in Cotton

TEs (transposable elements), particularly LTRs, are recognized to play a crucial role in defining basic genome organization and affecting functional gene expression. Insertion of TE or LTR fragments may also result in the formation of new transcription start sites (TSSs) in the host genome.

25 May 2023

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. I

24 May 2023

'Lost' Immune Cells Could be Partly Blamed for Impaired Vaccine Responses During Aging

Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.

23 May 2023

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Researchers have developed a chicken egg that may be safe for people with egg white allergies. Chicken egg allergies are one of the most common allergies in children.

18 May 2023

Learning More About Stem Cells Advances Personalized Regenerative Medicine

Organelles, which are made up of various protein and RNA fragments inside of a cell, are crucial for maintaining homeostasis, controlling aging and development, and producing energy.

16 May 2023

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

The immune system has a biological telecommunications system -; small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

8 May 2023

New Insights on Cases of Post-Vaccine Heart Inflammation

Public health experts discovered an increase in cases of myocarditis, an inflammation of heart muscle, after the introduction of the new COVID-19 vaccinations two years ago, particularly in young males who had received mRNA vaccines.

8 May 2023

New AI System Could Help Advance the Field of Generative Biology

Researchers at the University of Toronto have developed an artificial intelligence system that can create proteins not found in nature using generative diffusion, the same technology behind popular image-creation platforms such as DALL-E and Midjourney.

5 May 2023

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023