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Protein in skeletal muscular system may play a key role in the body's fight or flight response

Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful situations.

26 Apr 2021

New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.

17 Feb 2021

Researchers identify way to disrupt the process that promotes pancreatic tumor growth

Researchers say they've identified a way to disrupt a process that promotes the growth of pancreatic cancers -- one of the most difficult and deadly cancers to treat.

9 Dec 2020

Drug meant for bacterial infections can combat weight gain

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.

3 Dec 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Developing a new method to reduce antibiotic resistance in waterways

Dr. Aimee Murray speaks to AZoLifeSciences about her latest research that looks at a way of reducing antibiotic resistance build-up in waterways.

From University of Exeter 4 Nov 2020

Experimental vaccine shows promise for treating and preventing cancer in mice

An experimental vaccine, designed to enlist the body's own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice.

23 Oct 2020

New collaboration to develop machine learning methods for chemical discovery

The discovery and formulation of new drugs, antivirals, antibiotics and in general chemicals with tailored properties is a long and painstaking process.

21 Oct 2020

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival. (1-3)

24 Sep 2020

Combination treatment improves outcomes in advanced kidney cancer patients

An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. The pivotal study could lead to a new treatment option for patients with metastatic kidney cancer.

24 Sep 2020

Safe antibiotic levels can help fight the spread of drug-resistant bacteria

New research reveals current understanding of safe antibiotic levels in rivers may not prevent evolution of antibiotic resistance and fully protect human health. The study suggests the need to introduce thresholds to help fight the spread of resistant bacteria.

From University of Exeter 4 Sep 2020

Findings show new promise for using stem cells to treat enteric nervous system disorders

Scientists have made a breakthrough in understanding how the enteric nervous system forms, which could pave the way for new treatments for neurodegenerative diseases such as Parkinson's.

28 Aug 2020

Study reveals key biomolecule that can heal damaged heart tissues

When a person suffers a heart attack, parts of the heart can become stiff and scarred, leading to disability and possible progression toward heart failure.

26 Aug 2020

Study indicates a powerful treatment for pulmonary fibrosis

A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with idiopathic pulmonary fibrosis (IPF).

7 Aug 2020

AstraZeneca News and Research

Protein in skeletal muscular system may play a key role in the body's fight or flight response

New technique reveals the tricks that cancer cells use to avoid immunotherapies

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Researchers identify way to disrupt the process that promotes pancreatic tumor growth

Drug meant for bacterial infections can combat weight gain

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Developing a new method to reduce antibiotic resistance in waterways

Experimental vaccine shows promise for treating and preventing cancer in mice

New collaboration to develop machine learning methods for chemical discovery

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

Combination treatment improves outcomes in advanced kidney cancer patients

Safe antibiotic levels can help fight the spread of drug-resistant bacteria

Findings show new promise for using stem cells to treat enteric nervous system disorders

Study reveals key biomolecule that can heal damaged heart tissues

Study indicates a powerful treatment for pulmonary fibrosis

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Changes in glioblastoma cells influence the effect of different drugs, shows study

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