Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Men and women do have immune cell differences, study says

Researchers at the La Jolla Institute for Immunology have uncovered novel genes associated with the risk of autoimmune disorders in the CD4+ “helper” T cell subset.

2 Mar 2022

Immune cells in arteries can sniff out their surroundings and cause inflammation

An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.

17 Jan 2022

Researchers uncover a new signaling pathway essential for T cell viability

They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces.

23 Dec 2021

Study uncovers mechanisms behind rupture and repair of the nuclear envelope

The nucleus present inside the cell is surrounded by the nuclear envelope—two layers of phospholipid membrane that obstructs the nucleus from mixing with other parts of the cell—safeguarding the cell’s DNA from outside damage.

9 Dec 2021

Study identifies key proteins that damage skin cells in psoriasis

Psoriasis is an autoimmune disease that is characterized by patches of red, inflamed skin and painful, scaly rashes.

25 Nov 2021

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

Study identifies new gene that promotes progression to type 1 diabetes

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

17 Nov 2021

Apoptosis of mesenchymal stromal cells benefits therapeutic function

Scientists recently identified the therapeutic benefits to patients receiving mesenchymal stromal cell (MSC) therapy.

15 Nov 2021

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

8 Nov 2021

Supercomputer-driven dynamic model reveals hidden process in X chromosome inactivation

Using supercomputer-driven dynamic modeling based on experimental data, researchers can now probe the process that turns off one X chromosome in female mammal embryos.

5 Oct 2021

New molecule can effectively deplete cancer-protecting cells inside tumors

A new study has discovered a two-arm molecule that can effectively deplete cancer-protecting cells within tumors.

16 Aug 2021

Study proposes methods to purge unstable regulatory T cells

Scientists from the Babraham Institute, United Kingdom and VIB-KU Leuven, Belgium, came up with two solutions that can overcome a major clinical limitation of immune cell therapies. The researchers chose mice as their model. The findings were published recently in the journal Science Immunology.

27 Jul 2021

Autoimmunity News and Research

Men and women do have immune cell differences, study says

Immune cells in arteries can sniff out their surroundings and cause inflammation

Researchers uncover a new signaling pathway essential for T cell viability

Study uncovers mechanisms behind rupture and repair of the nuclear envelope

Study identifies key proteins that damage skin cells in psoriasis

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

Study identifies new gene that promotes progression to type 1 diabetes

Apoptosis of mesenchymal stromal cells benefits therapeutic function

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

Supercomputer-driven dynamic model reveals hidden process in X chromosome inactivation

New molecule can effectively deplete cancer-protecting cells inside tumors

Study proposes methods to purge unstable regulatory T cells

Research identifies vitamin C as a key ingredient for immune cell function

Subset of immune cells may carry out a sort of 'secondary education' to protect pregnancy

NCI grants over $4.2 million to launch the Cancer Epitope Database and Analysis Resource

Immune system’s killer T cells make mistakes in distinguishing healthy from infectious cell

Study identifies predictive causal role for specific cell types in type 1 diabetes

Study shows how WAVE2 protein maintains the immune system balance

Study shows how a subset of T cells is generated in melanoma survivors affected by vitiligo

Study reveals a new role of SRC-3 protein in various cancers

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