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Novel Antibiotic Discovery: Harnessing Energy Compounds to Combat Bacterial Infections

About a decade ago, researchers in UC Santa Barbara chemistry professor Guillermo Bazan's lab began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes.

22 Feb 2024

Mutation in E. coli's Cellulose Machinery Unveiled as Cause of Severe Infections

Queensland researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.

22 Feb 2024

Overlooked Sequence in Immunology Protein Holds Promise for New Autoimmune Therapies

Our immune system is remarkably powerful. It quickly assembles teams of cells to eliminate threats inside our bodies.

22 Feb 2024

Study Reveals Gut Microbiome's Influence on Premature Aging in Chronic HIV Patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., has demonstrated, with his lab and collaborators, a connection between viral damage to the gut and premature biological aging.

22 Feb 2024

Study Identifies Novel Enzyme Crucial for Bacterial Cell Wall Integrity

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls.

20 Feb 2024

Induction Cooktop Technology Shows Promise in Reducing Bacterial Infection in Prosthetic Joints

The same technology at work in induction cooktops cut the amount of bacteria present in a prosthetic joint infection when used in conjunction with antibiotics in a mouse model, UT Southwestern Medical Center researchers report in a new study.

19 Feb 2024

The Surprising Link Between Tea Quality and Root Bacteria

The type of tea used to make a fine cup of tea will significantly impact its flavor. However, a study published in the journal Current Biology reveals that the collection of bacteria found on tea roots is another essential component needed to make a great cup of tea.

16 Feb 2024

Mayo Clinic Researchers Analyze Zombie Cells to Explain Aging

With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules.

16 Feb 2024

Study Identifies Link Between Gut Microbiome Composition and Autism Spectrum Disorder

Autism Spectrum Disorder (ASD), a neurodevelopmental condition characterized by decreased social communication and repetitive behaviors, has long intrigued scientists seeking to unravel its underlying mechanisms.

14 Feb 2024

Hi-C Sequencing Unveils Phage-Host Dynamics in Soil Ecosystems

Bacteriophages-;viruses that infect bacteria-;are common in soil ecosystems.

14 Feb 2024

New Microbe Offers Economical Solution for Synthetic Biological Experiments

Cornell University researchers have created a new version of a microbe to compete economically with E. coli – a bacteria commonly used as a research tool due to its ability to synthesize proteins – to conduct low-cost and scalable synthetic biological experiments.

14 Feb 2024

Identifying Phosphorylation Sites in Legume-Rhizobia Symbiosis

Legume plants are unique in that they can interact with rhizobia, which are soil-dwelling bacteria that fix nitrogen.

13 Feb 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

Unraveling the Mystery of Tiny Insect-Killing Worm

Scientists at University of California, Riverside have found a small species of worm that attacks and destroys insects.

12 Feb 2024

Plant Peptides Guide Iron to Fuel Nitrogen Fixation

Researchers led by University of Tsukuba, based on the internal nitrogen status of a leguminous plant, have discovered peptide factors that function in the shoot and root systems to transport iron into the root nodules colonized by nitrogen-fixing bacteria.

7 Feb 2024