Bioengineering News and Research

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Nitrogen-Fixing Nodules Evolved More Than Once in Plants

Feeding the world's expanding population is made possible by nitrogen fertilizers, but their production is energy-intensive, expensive, and detrimental to ecosystems.

16 Jul 2024

Harnessing Enzymes for Making RNA Therapeutics

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis.

15 Jul 2024

Retron-Based Tool Enables Multi-Site DNA Editing

Genome editing has become a widely adopted technology to modify DNA in cells, allowing scientists to study diseases in the lab and develop therapies that repair disease-causing mutations.

10 Jul 2024

Unveiling the Power of mRNA and LNPs in Modern Medicine

Consider a situation in which an expert hacker has to upload vital software to update a central server and stop a potentially fatal virus from causing havoc on a sizable computer network.

10 Jul 2024

New Genetic Circuit Forces Cancer Cells to Self-Destruct

Treating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians never know when, where and what resistance might emerge, leaving them one step behind.

5 Jul 2024

Bridge RNA: The Revolutionary Tool in Genetic Recombination

In a leap forward for genetic engineering, a team of researchers from the Arc Institute have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way.

27 Jun 2024

3D Cell Cultures Improve Drug Screening Accuracy but Show Lower Efficacy for Anti-Cancer Drugs

The existing knowledge on monolayers and spheroid-based cell cultures, including the constituent compounds, and the difference in efficacy during drug screening, especially for anti-cancer drugs targeting cytoskeletal dynamics and cell cycles.

21 Jun 2024

New Microscopy Reveals Secrets of SARS-CoV-2 Replication

Recent research published in Nature Communications by a Stanford University team may provide more accuracy in drug development by examining at the nanoscale how the SARS-CoV-2 virus replicates in cells.

4 Jun 2024

Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes.

16 May 2024

MUSIC Map Uncovers Accelerated Aging in Brain Cells Linked to Alzheimer’s

Researchers observed sex-specific differences in the aging process of certain brain cells.

14 May 2024

Study Reveals Dual Contractility Modes in Cancer Cell Invasion

Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself.

8 May 2024

New AI Platform Generates Multi-Target Cancer Drug Candidates

Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen treatments.

7 May 2024

New Technique Reveals Microscopic Heart Vessels with Unprecedented Clarity

A new imaging technique tested in patients could improve the evaluation of cardiac conditions and undiagnosed chest pain.

7 May 2024

Using State-of-the Art Imaging to Understand Lipid Dysfunction in Alzheimer's

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

24 Apr 2024

Engineering Live Vaccines for Improved Immune Response

Bacterial proteins frequently outsmart the immune system, making it more challenging to fight off the bacteria that cause illnesses like staph infections.

5 Apr 2024

Engineering Bacteria to Grow Self-Dyeing Vegan Leather

Scientists at Imperial College London have modified bacteria genetically to produce leather that is free from animal products and plastic and has the ability to dye itself.

4 Apr 2024

Researchers Identify Protein Regulating Gas Vesicle Patterning in Bacteria

Gas vesicles are hollow structures made of protein found in the cells of certain microorganisms, and researchers at Rice University believe they can be programmed for use in biomedical applications.

30 Mar 2024

Groundbreaking Physics Study Offers Insights Into Self-Organization of Biological Particles

Erin McCarthy '23, physics summa cum laude, is a rarity among young scientists. As an undergraduate researcher in Syracuse University's College of Arts & Sciences' Department of Physics, she guided a study that appeared in March 2024 in Physical Review Letters. It is the most-cited physics letters journal and the eighth-most cited journal in science overall.

25 Mar 2024

The Assemblage of Nuclear Sub-Structures

Researchers from the lab of Rohit Pappu and associates at the Center for Biomolecular Condensates have figured out how nucleolar sub-structures are assembled, a first for the condensate field.

19 Mar 2024

The Incredible Impact of Mass Spectrometry on Brain Imaging

Researchers Jonathan Sweedler, a professor of chemistry, and Fan Lam, a professor of bioengineering, at the Beckman Institute for Advanced Science and Technology, described how spatial omics technologies can unveil the molecular complexity of the brain at various scales.

6 Mar 2024