CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.

19 Oct 2021

Study explores the effects of epigenetic editing in various tumor settings

Recent research reports that the appropriate functioning of this mechanism is essential for tissue homeostasis and cell fate determination.

13 Oct 2021

Does the Future of Farming Involve the Gene Editing of Farm Animals?

In this interview, AZoLifeSciences speaks to the RSPCA about the future of farming, and whether it involves gene-edited farm animals.

8 Oct 2021

Study offers important insights into how circadian clocks function at the subcellular level

Almost every living thing on Earth-;from bacteria to plants to people-;have a circadian rhythm, the biological clock that controls both physiology and behavior of organisms over a 24-hour period.

1 Oct 2021

Study unravels factors involved in risiRNA generation

A team of scientists disclosed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism.

1 Oct 2021

Experts unravel inner workings of cell receptors involved in various diseases

Scientists revealed the operational mechanism of possible drug targets for numerous diseases like rheumatoid arthritis, cancer, and even COVID-19.

1 Oct 2021

Researchers explore the regulation of suberin in Arabidopsis thaliana

Plants modify the permeability of their roots to adapt to their nutritional needs. This takes place through the degradation or production of suberin.

27 Sep 2021

Hundreds of mutated tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

17 Sep 2021

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

14 Sep 2021

New scalable genetic control system to restrain disease-spreading mosquitoes

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

13 Sep 2021

Study unearths previously unknown role of CTCF, the transcription regulator

Researchers discovered evidence that CTCF governs chromatin accessibility, the mechanism of opening tightly spooled DNA facilitating gene expression.

9 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

New approach to enhance cell-free biosynthesis with engineered yeast extracts

Think of cells as tiny factories: within their walls they have both the machinery to make products such as proteins, and the mechanisms for maintenance to keep processes running smoothly.

31 Aug 2021

Genome editing tool used to render male mosquitoes infertile and slow disease spread

Mosquitos spread viruses that cause potentially deadly diseases such as Zika, dengue fever and yellow fever. New U.S. Army-funded research uses gene editing to render certain male mosquitoes infertile and slow the spread of these diseases.

24 Aug 2021

New CRISPR-based technique for rapid screening of hundreds of genes in a single experiment

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

20 Aug 2021

Researchers modify CRISPR to enable antibody-based medical diagnostics

Researchers adapted CRISPR to analyze antibodies in patient blood samples to pave the way for a new class of medical diagnostics.

16 Aug 2021

New technique can map out nearly all of the regulatory switches across a maize genome

Getting a full understanding of how genes are regulated is a major goal of scientists worldwide. Now, a Florida State University professor and his research partners have developed a technique that can map out nearly all of the likely regulatory switches across a genome.

16 Aug 2021

CRISPR News and Research

Further Reading

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Study explores the effects of epigenetic editing in various tumor settings

Does the Future of Farming Involve the Gene Editing of Farm Animals?

Study offers important insights into how circadian clocks function at the subcellular level

Study unravels factors involved in risiRNA generation

Experts unravel inner workings of cell receptors involved in various diseases

Researchers explore the regulation of suberin in Arabidopsis thaliana

Hundreds of mutated tumor suppressor genes can help cancer cells evade the immune system

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

New scalable genetic control system to restrain disease-spreading mosquitoes

Study unearths previously unknown role of CTCF, the transcription regulator

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

Miniature CRISPR-Cas system expands applicability and implications further

Genetically engineered cells deliver drugs in response to inflammation

New approach to enhance cell-free biosynthesis with engineered yeast extracts

Genome editing tool used to render male mosquitoes infertile and slow disease spread

New CRISPR-based technique for rapid screening of hundreds of genes in a single experiment

Researchers modify CRISPR to enable antibody-based medical diagnostics

New technique can map out nearly all of the regulatory switches across a maize genome

World Soil Day: An Interview with the Food and Agricultural Organisation (FAO)

How is Climate Change affecting Global Agriculture?

De novo mutations may play a role in male infertility

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