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Protein known to mediate cell death plays a key role in maturation and release of interleukin-1α

Interluekin-1α (IL-1α) is an important part of the immune response, but until now it has been unclear how this molecule is processed from its precursor, pro-IL-1α, and exits the cell during inflammasome activation.

21 Jun 2021

Study reveals how cells “read” synthetic ingredients added to a genetic code

If the genome is considered the recipe for life, then base pairs represent the individual ingredients. DNA is made up of these chemical structures, and every living thing on the planet has just four of them.

21 Jun 2021

New method to control the complex communication network of cells

A study has proposed a new method for developing novel drugs based on the suppression of tyrosine kinase enzymes.

21 Jun 2021

A new treatment approach against SARS-CoV-2

Scientists have come up with a new method to treat SARS-CoV-2 infection by fixing the cell damage instead of fighting the virus directly.

21 Jun 2021

Inhibition of necroptosis may be a new therapeutic approach to treating COPD

Research shows that inhibiting necroptosis, a form of cell death, could be a novel therapeutic approach for treating chronic obstructive pulmonary disease (COPD), an inflammatory lung condition, also known as emphysema, that makes it difficult to breathe.

21 Jun 2021

Genetically engineering NK cells can target and kill glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

18 Jun 2021

Presence of certain stem cells correlates with non-genetic resistance mechanisms to cancer drugs

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

Natural killer cells target breast cancer using the body’s immune system

In a recent study, researchers investigated how natural killer cells target breast cancer using the body's own immune system.

18 Jun 2021

'Enabler cells' in tumors could promote cancer metastasis

Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists.

17 Jun 2021

Researchers systematically analyze alternative splicing in the family of glutamate receptors

Alternative splicing can lead to the formation of numerous protein variants. For the first time, alternative splicing has now been systematically analysed for the family of glutamate receptors.

17 Jun 2021

Novel technique greatly increases the resolution of atomic force microscopy

Scientists at Weill Cornell Medicine have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that "feels" the atoms at a surface.

17 Jun 2021

Study decodes the activation mechanism of immune cells

Chemokines are small proteins that adhere to these chemokine receptors and regulate the behavior and movement of white blood cells.

17 Jun 2021

Newly identified protein regulates the flow of materials in the Drosophila ovary

According to a research work performed by Northwestern Medicine and published in the Current Biology journal, a protein helps guide the flow of materials in the ovary of Drosophila fruit flies during the formation of egg cells.

17 Jun 2021

Advanced video microscopy reveals molecular details of malaria invasion

Using cutting-edge video microscopy, researchers have successfully observed the molecular intricacies of how malaria parasites enter red blood cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 17 Jun 2021

Study reveals the key role of motor proteins in mitotic spindle elongation

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the molecular mechanism that drives spindle elongation in human cells has been unknown, until now!

16 Jun 2021

AI model helps predict which viruses are likely to spread from animals to humans

A new model that applies artificial intelligence to carbohydrates improves the understanding of the infection process and could help predict which viruses are likely to spread from animals to humans. This is reported in a recent study led by researchers at the University of Gothenburg.

16 Jun 2021