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Research Reveals the Impact of Activated Protein C on Alzheimer's Disease Pathology

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 4, entitled, "Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C."

14 Mar 2024

Dual-Target CAR T Cell Therapy Shows Promise Against Recurrent Glioblastoma

Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2024

Study Reveals Key Role of STAP-1 in Immune Function

A recent study has illuminated the significance of the protein STAP-1 in activating specific immune cells.

13 Mar 2024

Investigating the Antibacterial Effects of T1-Spanin on Antibiotic-Resistant Bacteria

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13 Mar 2024

The Evolution of Plant Cell Analysis with RevGel-seq Technique

Plant cell analysis has been completely transformed by recent advances in single-cell RNA sequencing (scRNA), such as the recently created “RevGel-seq” technique.

13 Mar 2024

Study Reveals Unique Bacterial Fingerprints and Their Impact on Health

The trillions of bacteria that call your body home -; collectively known as the microbiome -; appear to be unique to you, like a fingerprint.

13 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024

Study Identifies Protein Key to Preserving Neuronal Identity

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

13 Mar 2024

NIH Researchers Map Vulnerable Sites on Epstein-Barr Virus gp42 Protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

13 Mar 2024

Small Genetic Element Identified as Key to Potato Industry's Production Problem

Researchers have discovered a game changer for the potato industry.

12 Mar 2024

Scientists Pinpoint Gene Linked to Neuronal Susceptibility in Alzheimer’s Disease

Protein buildup and cell degeneration in specific populations of brain cells are hallmarks of the early stages of neurodegenerative diseases.

12 Mar 2024

Electron Microscope Unlocks Secrets of the Commander Complex

Receptor molecules on the cell surface are essential for cellular communication. Periodically, these receptors must be absorbed and sorted for them to be broken down or recycled.

12 Mar 2024

Study Reveals STAP-1 Protein's Role in Immune Disorders

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

12 Mar 2024

Reducing Iron May Reverse Stem Cell Aging

It is fascinating to learn how researchers at the Albert Einstein College of Medicine and the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have discovered a way to prevent or even reverse the function of hematopoietic (blood-forming) stem cells (HSCs) as they age.

11 Mar 2024

The Surprising Impact of Chaperone Proteins on Multicellular Evolution

In a recent study, scientists used an instrument known as “experimental evolution” under the direction of researchers from the University of Helsinki and the Georgia Institute of Technology.

11 Mar 2024

Breakthrough Study Reveals Key Mechanism in Passing Epigenetic Information During Cell Division

A research team led by Professor Yuanliang ZHAI at the School of Biological Sciences, The University of Hong Kong collaborating with Professor Ning GAO and Professor Qing LI from Peking University, as well as Professor Bik-Kwoon TYE from Cornell University, has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division.

11 Mar 2024

Blood-Based Markers Unveil Secrets of Biological Aging

University of Pittsburgh researchers have uncovered blood-based markers linked with healthy and rapid aging, allowing them to predict a person's biological age -; how fast a person's cells and organs age regardless of their birthdate.

11 Mar 2024

uLIPSTIC Tool: Tracking Cell-to-Cell Interactions

Gaining an understanding of how various cell types cooperate to form tissues, organs, and organ systems is one of the main objectives of basic biology.

8 Mar 2024

The Incredible Impact of Mass Spectrometry on Brain Imaging

Researchers Jonathan Sweedler, a professor of chemistry, and Fan Lam, a professor of bioengineering, at the Beckman Institute for Advanced Science and Technology, described how spatial omics technologies can unveil the molecular complexity of the brain at various scales.

6 Mar 2024

The Impact of Catalysis for Site-Specific Protein Modification

As they recently reported in the journal Nature Chemistry, Boston College researchers have developed a new tool that can be used to develop novel biotherapeutics and protein-based research tools: the ability to precisely modify proteins using a mild charge of electricity.

6 Mar 2024