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Broad Spectrum Pathogen Detection Achieved Through Metagenomic Sequencing

A recent study on the application of Metagenomic next-generation sequencing (mNGS) found that mNGS can achieve early detection of pathogens and accelerate the development of targeted anti-infection treatment plans, thereby improving treatment outcomes and patient prognosis.

24 May 2025

New Stem Cell Islet Model Mimics Pancreatic Function More Accurately

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

24 May 2025

Machine Learning Reveals Molecular Profile Differences in Colorectal Cancer Patients

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

24 May 2025

Scientists Engineer Proteins That Morph Like Nature’s Own

The ability to engineer shapeshifting proteins opens new avenues for medicine, agriculture, and beyond.

24 May 2025

New Genomic Score Predicts Risk of Progression in Multiple Myeloma

A new risk assessment score developed by researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard reveals how multiple myeloma, a form of blood cancer, begins and progresses from precancerous to malignant states by tracing DNA mutations.

24 May 2025

New Bacterial Consortium can Inhibit Bacterial Pathogens in Aquaculture

A new study by Danish researchers has demonstrated that it is possible to develop a consortium of bacteria that can inhibit bacterial pathogens in aquaculture.

22 May 2025

Study Reveals Epigenetic Clues Behind Autism Development

Autism spectrum disorder (ASD) is a condition affecting the brain's development and often affects the ability of a person to perceive sensory information and social cues and socialize with others.

22 May 2025

Ultra-Rapid Genetic Test Revolutionizes Brain Tumor Diagnosis

Scientists and medics have developed an ultra-rapid method of genetically diagnosing brain tumors that will cut the time it takes to classify them from 6-8 weeks, to as little as two hours – which could improve care for thousands of patients each year in the UK.

21 May 2025

Cell Painting Technology Reveals Potential Cancer-Fighting Flavonoids

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

21 May 2025

Geisinger Scientists Uncover Genetic Basis for Sex-Based Height Variation

Geisinger's study reveals Y chromosome genes significantly influence height differences between sexes, highlighting genetic factors beyond hormones.

21 May 2025

Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

Understanding Particle Drift and its Influence on Oral Drug Absorption Using Flux Tools

Explore how particle drift influences oral drug absorption and why flux tools are essential for accurate assessment.

From Pion Inc 19 May 2025

Carriers of Recessive Disorders Face Hidden Health and Reproductive Problems

As a group, carriers of recessive disorders are slightly less healthy and have a reduced chance of having offspring.

16 May 2025

Protein Balance Offers Key to Overcoming Immunotherapy Resistance

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy that block specific proteins from slowing the immune response.

15 May 2025

Loss of SOX9 Gene Linked to Aggressive Colorectal Cancer

Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes associated with colorectal cancer are known, how they contribute to cancer development is not yet well defined.

15 May 2025

Novel Role for Disordered Protein in Coordinating Key Stages of Gene Expression

Research reveals TAF2's disordered region links transcription and RNA editing, highlighting its role in gene expression regulation and nuclear organization.

15 May 2025

CAR-T Cell Therapy Causes “Brain Fog,” Independent of Other Cancer Treatments

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

13 May 2025

Potential Therapeutic Target for Aggressive Colorectal Cancers

Colorectal cancer ranks as the second leading cause of cancer-related mortality worldwide.

13 May 2025

Depleting TM6SF2 in the Gut Worsens Liver Fat Buildup, Study Finds

A new study finds that gut-specific TM6SF2 depletion exacerbates liver fat accumulation and dysbiosis in mice on high-fat diets, highlighting its importance in gut-liver metabolic regulation.

12 May 2025