Cohesin is the protein responsible for binding the sister chromatids during mitosis after S phase. At metaphase, most cohesin is removed, except for some at the centromere. At Anaphase, securin, an inhibitory subunit of separase, is hydrolyzed.
Each biological process depends on pH in one way or another. The human body should maintain constant and specific pH regulation to function efficiently.
Researchers from the University of Tsukuba have identified a novel protein complex that regulates Aurora B localization to ensure that chromosomes are correctly separated during cell division.
Researchers have demonstrated that a dysfunctional placenta can play a formerly unknown role during the earliest phases of development in Cornelia de Lange.
During the process of each single cell division, the chromosomal genetic data should be uniformly distributed between the freshly developing daughter cells.