DNA Replication News and Research

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DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.

Super-resolution technology helps visualize DNA replication in single human cells

DNA replication is a process of critical importance to the cell, and must be coordinated precisely to ensure that genomic information is duplicated once and only once during each cell cycle.

26 Jun 2020

KAUST scientists reveal the genetic metronome within malaria parasites

The parasites responsible for malaria seem to march to their own beat.The mystery behind the molecular basis of how these parasites synch their rhythm in replication to the host's clock-driven rhythms has been solved.

10 Jun 2020

Study demonstrates the role of p53 gene in cell cycle regulation and apoptosis

The p53 gene is crucial in cell biology and thus cell replacement therapy. The function of this gene is to control the cell cycle and stop tumor formation.

2 Jun 2020

Study reveals proteins that sustain cancer cells

Scientists from the University of Copenhagen have identified two major functions of the protein known as RTEL1 during cell division, in a recently performed study.

14 May 2020

Choosing alternate pathways of DNA repair to limit harmful chromosomal rearrangements

Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism.

From Osaka University 30 Apr 2020

Researchers study the evolution of multidrug-resistant bacteria

Although antibiotics are known to save lives, their use also supports the evolution and spread of antibiotic-resistant strains.

29 Apr 2020

More efficient, cost-effective method for accurate synthesis of DNA

DNA is a genetic material that continues to survive only through replication, either naturally or synthetically. Humans require reproduction of DNA to replace damaged or old cells, but the potential to replicate DNA in a laboratory setting can allow scientists understand the disease mechanisms or the platform to develop treatments.

17 Mar 2020