Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.
Parkinson’s disease is a neurodegenerative disorder and melanoma is a type of skin cancer but on the surface, these disorders do not seem to have much in common.
Neurons cannot simulate their DNA and hence they work continuously to repair any damage caused to their genome.
Neuroscientists agree that a person's brain is constantly changing, rewiring itself and adapting to environmental stimuli. This is how humans learn new things and create memories. This adaptability and malleability is called plasticity.
According to a study, researchers have discovered new genetic clues in individuals who had experienced small but often apparently “silent” strokes.
Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.
Scientists from the University of Leeds's Nutritional Epidemiology Group used data from 500,000 people, discovering that consuming a 25g serving of processed meat a day, the equivalent to one rasher of bacon, is associated with a 44% increased risk of developing the disease.
A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.
AZoLifeSciences speaks to researchers from Tianjin Medical University about their latest research that led to the discovery of two new genes that are linked to Alzheimer's disease.
Neurodegenerative diseases, such as various forms of senile dementia or amyotrophic lateral sclerosis (ALS), have one thing in common: large amounts of certain RNA-protein complexes (snRNPs) are produced and deposited in the nerve cells of those affected - and this hinders the function of the cells.
Tohoku University scientists have shown that neuronal and glial circuits form a loosely coupled super-network within the brain.
Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.
Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele.
Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.
A research team from Geisinger Health System has detected a common genetic variant as a risk factor for stroke, particularly in patients aged more than 65.
Scientists from the Pacific Quantum Center of Far Eastern Federal University (FEFU) figured out how the AFV3-109 protein with slipknot structure folds and unfolds depending on temperature. The protein is typical for the viruses of the oldest single-celled organisms that can survive in the extreme conditions of underwater volcanic sources - archaea. The research outcome appears in PLOS ONE.
Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away.
The research group led by Dr Sjoerd van Wijk from the Institute of Experimental Cancer Research in Paediatrics at Goethe University already two years ago found evidence indicating that the anti-diarrhea drug loperamide could be used to induce cell death in glioblastoma cell lines.
Getting computers to "think" like humans is the holy grail of artificial intelligence, but human brains turn out to be tough acts to follow. T
Ocean pollution is widespread and getting worse, and when toxins in the oceans make landfall they imperil the health and well-being of more than 3 billion people, according to a new report by an international coalition of scientists led by Boston College's Global Observatory on Pollution on Health and the Centre Scientifique de Monaco, supported by the Prince Albert II of Monaco Foundation.
Scientists from The Mount Sinai Hospital and the National Center for Geriatrics and Gerontology based in Japan have recently discovered novel molecular mechanisms that drive late-onset Alzheimer’s disease (LOAD).