Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.
Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.
Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.
According to Johns Hopkins Medicine researchers, they have devised a computer model called quantitative fate mapping that looks back in time to track the origin of cells in a fully grown organism.
Researchers at UF Scripps Biomedical Research have created a potential treatment for a major factor in the development of ALS and dementia that functions by removing disease-causing RNA segments.
Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.
Prof. Kiavash Movahedi (VUB, VIB) headed a group that outlined how the immune system responds to infections entering the brain. The results offer new information on host-pathogen interactions as well as the long-term effects of brain infections.
A recent Baycrest study points to the possibility that the gut microbiome influences how nutrition and exercise impact brain health and dementia risk. Physicians and researchers could be able to improve dementia prevention efforts with the use of this knowledge.
The breakthrough study from the University of Sheffield’s Neuroscience Institute and Healthy Lifespan Institute offers critical new insights into the so-called junk DNA, or DNA that was previously believed to be unimportant to the coding of the genome, and how it affects neurological disorders like Motor Neuron Disease (MND) and Alzheimer’s.
Special blood vessels in whale brains may protect them from pulses, caused by swimming, in their blood that would damage the brain, new UBC research has suggested.
Principal researchers at the Brain Science Institute (BSI) of the Korea Institute of Science and Technology were said to have discovered substantially decreased activity of focal adhesion kinase (FAK) proteins that play a significant role in neurite motility and proper synapse formation in HD patients’ brain tissues.
Researchers from UC, the University of Illinois Urbana-Champaign, and the University at Buffalo demonstrated that light-activated proteins can help normalize dysfunction within cells.
There are no disease-modifying therapies for Parkinson’s disease that can alter the course of the disease.
The prescription humans use to manage high blood pressure, discomfort, or memory loss may one day originate from modified bacteria, cultivated in a vat like a yogurt, offering more inexpensive, sustainable drug options than people now have.
DZNE and Intravacc B.V., have received a grant from the European Union of € 2.5 million to further create a prototype ALS vaccine.
The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.
Researchers employed gene editing to switch off a specific component in the tomato plant’s DNA, which led to an increase in provitamin D3 in both the fruit and leaves. After that, UVB light was used to convert it to vitamin D3.
Amyloidosis is a term used to describe a group of diseases defined by the formation of insoluble proteins called amyloids outside of cells as a result of misfolding and aggregation of soluble proteins.
Recently, researchers have discovered a novel method that could help avoid the formation of protein tangles, which are typical in dementia.
Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.
The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?