Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.
Scientists from Trinity College Dublin have discovered a new link between impaired brain energy metabolism and delirium - a disorienting and distressing disorder particularly common in the elderly and one that is currently occurring in a large proportion of patients hospitalized with COVID-19.
Across the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal lobar degeneration (FTLD), which develop when neurons in specific parts of the brain stop functioning - triggering memory loss and other behavioral or personality changes.
Neurons in the brains of such people are being depleted gradually and inevitably, resulting in the characteristic loss of cognitive function and memory.
Researchers at the University of Maryland School of Medicine have identified how certain gene mutations cause amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.
Toxic versions of the protein tau are believed to cause the death of neurons of the brain in Alzheimer's disease.
Having a faulty gene linked to dementia doubles the risk of developing severe COVID-19, according to a large-scale study.
Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.
We know a lot about the human brain, but very little about how it is formed. In particular, the stages from the second to the seventh week of embryonic development have so far been virtually unknown territory to brain researchers.
MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.
AZoLifeSciences speaks to Professor Long Nam Nguyen about his research which led to the discovery of a protein that controls brain-blood vessel development.
Researchers from Harvard University have discovered a new link between the gut and the brain in ALS, a neurodegenerative disease.
Older adults who consumed small amounts of flavonoid-rich foods were two to four times more likely to develop Alzheimer's disease and related dementias.
Researchers from the HudsonAlpha Institute for Biotechnology, UCSF, and UAB have discovered a new risk factor for various neurodegenerative diseases.
It is no secret that a healthy diet may benefit the brain. However, it may not only be what foods you eat, but what foods you eat together.
People with a gene that puts them at risk for Alzheimer's disease are protected from its debilitating effects if they also carry a variant of a different gene.
In the largest study to date of proteins related to Alzheimer's disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers.
In a study published recently in the eLife journal, researchers have reported that the combined effects of rare and damaging mutations that occur at birth itself have adverse effects on health span and longevity.
In an international study published recently, researchers from the University of Saskatchewan report that combined scientific effort would be needed to assemble and map the genome of cannabis to unravel its full potential for human health and agriculture.