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Constructing a Structured Illumination Microscopy Add-On

EPFL scientists have recently released a comprehensive manual detailing the construction of an add-on that can transform a regular optical microscope into a cutting-edge tool capable of generating high-resolution, three-dimensional images of cells, organoids, and embryos.

5 Mar 2024

New Research Sheds Light on Divergent Roles of Paralogous RNA Helicases

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

9 Feb 2024

Deciphering the Structure and Function of PLD3 in Cellular Waste Disposal

If we don't take out the trash regularly, our homes become unpleasant and even a danger to our health.

21 Dec 2023

Revealing How Copper Amine Oxidase Enzymes Stabilize Radical Intermediates

The human body heals wounds or detoxifies harmful substances like histamine with the help of a group of enzymes called copper amine oxidases.

20 Sep 2023

Identifying The Best Antibodies Using X-Rays

Imagine you're going to a party where you only know a single person. While you've been friends with this person for a long time, you're concerned about them leaving you alone in a room full of strangers. Even though they promise they'll stick by your side, they immediately walk away from you upon entering the party to speak to someone else they know.

26 Jul 2023

Berkeley Lab and Genentech Team Up to Develop Next-Generation Drug Delivery System

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

18 Jul 2023

Scientists Develop Method to Create Artificial Allosteric Sites in Protein Complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

7 Jul 2023

Innovative Technique Enables In Vivo Imaging of Intracellular Protein Aggregates

Tau aggregates have become the main study focus for figuring out the mechanisms underlying neurodegeneration since they are a prevalent form of amyloid protein. Tau fibrils and oligomers, among other forms of tau aggregates, have been linked to a variety of neurodegenerative disorders.

21 Jun 2023

New Algorithm to Improve the Understanding of Protein Movements

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

31 May 2023

New Method for Analyzing Protein Crystals Could Open Up Applications for Drug Discovery

A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and biochemistry.

12 May 2023

New method triggers and analyzes the dynamics of brain protein linked to Alzheimer’s

Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative diseases.

15 Feb 2023

Plants can precisely tune the chemistry of petal surface to create bee-luring signals

Cambridge researchers led by CUBG Director, Professor Beverley Glover, have shown that plants can regulate the chemistry of their petal surface to create iridescent signals visible to bees.

25 Nov 2022

Meet Dragonfly 600, Oxford Instruments’ new flagship confocal microscope

Oxford Instruments Andor, a world leader in scientific imaging solutions, has today announced the launch of Dragonfly 600, further strengthening its award-winning confocal microscopy portfolio.

From Andor Technology Ltd. 10 Nov 2022

High-throughput quantitative phase microscopy yields promising results

Numerous cellular life processes include the organelles of cells. Their malfunction and the growth and spread of cancer are strongly connected.

4 Nov 2022

Researchers discover the atomic structure of the nuclear pore complex

Nearly 100 trillion cells make up the human body, which is what keeps people healthy and alive. The mechanisms of life are maintained by the billions of pieces that each cell has on its own.

14 Jul 2022

$Access to the Rigaku’s Electron Diffraction Technology without the Capital Outlay$

Access to the Rigaku’s Electron Diffraction Technology without the Capital Outlay

With convenient and economical access to Rigaku’s state-of-the-art electron diffraction capabilities and applications experts, crystallization trials on samples smaller than 1 micron no longer need to delay your structural analysis programs.

From Rigaku Corporation 25 May 2022

Rigaku Pharma Forum 2022 for Advanced Analytical Solutions Used in Industry and Research

Rigaku is proud to be hosting the inaugural Pharma Forum, a free-to-attend, two-day virtual event from April 27-28, 2022. The forum examines a range of analytical techniques and how these can be applied during the development, formulation, and manufacture of pharmaceuticals.

From Rigaku Corporation 4 Apr 2022

Researchers show how hotspot maps can detect structures contributing to compounds’ selectivity

The quantity of structural data available on protein drug targets keeps growing.

4 Mar 2022

Researchers develop enhanced version of microscope that produce high-throughput 3D adaptive optical imaging

Microscopes are chosen to be a helpful tool in biomedical research as they permit for close inspection and visualization of tissues.

15 Feb 2022

Model system for biofilms studied at the BESSY II

Bacterial biofilms can thrive on almost all types of surfaces: We find them on rocks and plants, on teeth and mucous membranes, but also on contact lenses, medical implants or catheters, in the hoses of the dairy industry or drinking water pipes, where they can pose a serious threat to human health.

1 Feb 2022