Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
New method to synthesize complex bioactive molecules quickly and efficiently

New method to synthesize complex bioactive molecules quickly and efficiently

Drug-like compounds previously developed to fight SARS may also work against COVID-19

Drug-like compounds previously developed to fight SARS may also work against COVID-19

Protein structural study may lead to more improved research on disease development

Protein structural study may lead to more improved research on disease development

New technique could accelerate drug research for various diseases

New technique could accelerate drug research for various diseases

HPSC-based disease modeling can help treat heart diseases

HPSC-based disease modeling can help treat heart diseases

Researchers use genome editing to facilitate drug discovery based on natural fungus

Researchers use genome editing to facilitate drug discovery based on natural fungus

Researchers are developing therapeutic treatments for acute stroke

Researchers are developing therapeutic treatments for acute stroke

Machine learning can increase effectiveness of drug repurposing for psychiatric disorders

Machine learning can increase effectiveness of drug repurposing for psychiatric disorders

Sterile deep well plates

Sterile deep well plates

A simple screening process may improve mAb-based drug development

A simple screening process may improve mAb-based drug development

A new cell-based gene therapy approach to correct hemophilia A

A new cell-based gene therapy approach to correct hemophilia A

New technology can speed up drug development for tuberculosis

New technology can speed up drug development for tuberculosis

Reactivating divergent signaling pathways to enhance cancer treatment

Reactivating divergent signaling pathways to enhance cancer treatment

Quality of lab procedures has a big impact on discovery of effective drugs

Quality of lab procedures has a big impact on discovery of effective drugs

Study shows how cells respond to nutrient deprivation

Study shows how cells respond to nutrient deprivation

uEXPLORER TB-PET/CT scanner captures complete picture of systemic inflammatory arthritis

uEXPLORER TB-PET/CT scanner captures complete picture of systemic inflammatory arthritis

Researchers discover promising drug candidate for treatment of brain disorders

Researchers discover promising drug candidate for treatment of brain disorders

New drug enables the immune system to attack ovarian cancer, TGen study shows

New drug enables the immune system to attack ovarian cancer, TGen study shows

X-ray method helps track protein folding

X-ray method helps track protein folding

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution