Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Diagnostic Biochips: Brain Research Tools for the Future

In this interview, we delve into the innovative world of Diagnostic Biochips with its founder, Brian Jamieson. He shares insights into the company's inception, its contributions to advancing brain research, and the future of neural interfacing technology.

1 Feb 2024

Promising Drug Offers Hope for Overcoming Resistance to Protein Degraders

Protein degraders, a novel approach in drug discovery, show promise to tackle diseases previously thought to be untreatable.

31 Jan 2024

Formulatrix® and Olink® Announce Collaboration to Deliver Automated Proteomics Research Solutions to Enable Protein Detection with Exceptional Precision and Speed

Formulatrix, a leader in innovative automated liquid handling technologies, announced a multi-year collaboration and supply agreement to advance the automation of Olink’s PEA (Proximity Extension Assay) technology, including the Target 96, Target 48, Flex, and Explore workflows.

From FORMULATRIX 31 Jan 2024

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Bio-Techne Corporation (NASDAQ: TECH) today announced that its spatial biology brands, Lunaphore and Advanced Cell Diagnostics (ACD), will launch the first fully automated spatial multiomics workflow with same-section hyperplex detection of RNA and protein biomarkers.

From Bio-Techne 25 Jan 2024

Revolutionizing Drug Discovery with Novel Sulfur Compound Synthesis

Over the past decade, there has been significant progress in the development of novel sulfur-containing compounds utilized across diverse industries, including pharmaceuticals and agricultural products.

23 Jan 2024

Stem Cell-Derived Brain Organoids on Ax-3 Mission Seek to Improve Modeling for Neurodegenerative Diseases

More than 5 million people worldwide are living with neurodegenerative disorders like Parkinson’s disease and primary progressive multiple sclerosis (PPMS).

19 Jan 2024

Commercializing Innovation in a Life Sciences Ecosystem

In this interview, Glennis Mehra, the Director of BioLabs at NYU Langone, shares her journey through the life sciences industry and delves into the role of BioLabs as an incubator for early-stage life science companies.

17 Jan 2024

Algal Blooms May Pose More Health Risks Than Previously Thought

Florida's 156-mile-long Indian River Lagoon (IRL) borders five different counties and has five inlets that connect the lagoon with the Atlantic Ocean.

16 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024

Improved Mapping of Small-Molecule Binding Sites in Cells

Researchers at Scripps Research created a novel, high-resolution method for identifying putative treatment targets on proteins in living cells.

3 Jan 2024

AI-Powered Drug Breakthrough: Insilico Unveils Potent FGFR2/3 Inhibitor for Solid Tumors

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

29 Dec 2023

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.

26 Dec 2023

Innovative Machine Learning Tool Predicts Functional Consequences of Genetic Variants

In a recent research, scientists from the Icahn School of Medicine at Mount Sinai unveiled LoGoFunc, an innovative computational tool designed to forecast both pathogenic gain- and loss-of-function variants throughout the genome.

15 Dec 2023

Understudied Brain Cell Holds Key to Glioblastoma's Immunotherapy Resistance

Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years.

13 Dec 2023

Free AI Drug Discovery Course Surpasses 2,500 Users

An online course on Disease Modeling and Target Discovery launched 7 months ago by clinical stage generative artificial intelligence (AI)-driven biotechnology company Insilico Medicine has surpassed 2,500 users.

12 Dec 2023

SFU-UBC Collaboration Pushes Frontiers of Cellular Biology With AI-Enhanced Super-Resolution Microscopy

In 2014, the Nobel Prize in Chemistry celebrated the breakthroughs in super-resolution microscopy, a technology that allows us to capture highly detailed images of small parts of cells using fluorescent microscopy.

11 Dec 2023

Camena Bioscience Appoints Dr. Nicola Thompson as Chair of the Board

Camena Bioscience, a synthetic biology company providing genes to the pharmaceutical and biotechnology industries, today announced it has appointed Dr Nicola Thompson as Chair of its Board of Directors.

From Camena Bioscience 6 Dec 2023

Algorithmiq Demonstrates Path to Quantum Utility with IBM

Algorithmiq, a scaleup developing quantum algorithms to solve the most complex problems in life sciences, has successfully run one of the largest scale error mitigation experiments to date on IBM’s hardware.

6 Dec 2023

Discovery Park Ventures Expands Fund to £3m to Invest in More Innovative Science and Technology Start-Ups

Discovery Park Ventures (DPV) announces the expansion of its early-stage life science fund from £1m to £3m, in order to capitalise on exciting investment opportunities and support its existing portfolio.

5 Dec 2023

Could A Small Flower Hold The Key to More Stable Peptide Drugs?

Taking inspiration from a small purple flower found in the tropics, University of Bath scientists have successfully created a new tool that could help to create more stable, efficient and cost-effective drugs.

29 Nov 2023

Drug Discovery News and Research

Further Reading

Diagnostic Biochips: Brain Research Tools for the Future

Promising Drug Offers Hope for Overcoming Resistance to Protein Degraders

Formulatrix® and Olink® Announce Collaboration to Deliver Automated Proteomics Research Solutions to Enable Protein Detection with Exceptional Precision and Speed

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Revolutionizing Drug Discovery with Novel Sulfur Compound Synthesis

Stem Cell-Derived Brain Organoids on Ax-3 Mission Seek to Improve Modeling for Neurodegenerative Diseases

Commercializing Innovation in a Life Sciences Ecosystem

Algal Blooms May Pose More Health Risks Than Previously Thought

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

Improved Mapping of Small-Molecule Binding Sites in Cells

AI-Powered Drug Breakthrough: Insilico Unveils Potent FGFR2/3 Inhibitor for Solid Tumors

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Innovative Machine Learning Tool Predicts Functional Consequences of Genetic Variants

Understudied Brain Cell Holds Key to Glioblastoma's Immunotherapy Resistance

Free AI Drug Discovery Course Surpasses 2,500 Users

SFU-UBC Collaboration Pushes Frontiers of Cellular Biology With AI-Enhanced Super-Resolution Microscopy

Camena Bioscience Appoints Dr. Nicola Thompson as Chair of the Board

Algorithmiq Demonstrates Path to Quantum Utility with IBM

Discovery Park Ventures Expands Fund to £3m to Invest in More Innovative Science and Technology Start-Ups

Could A Small Flower Hold The Key to More Stable Peptide Drugs?

Drug Discovery eBook

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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