Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

Study discovers actionable DNA errors remain stable over time

Study discovers actionable DNA errors remain stable over time

Graphene covered with bactericidal molecules inhibits harmful biofilm formation

Graphene covered with bactericidal molecules inhibits harmful biofilm formation

Researchers create new drug database to facilitate repurposing of drugs

Researchers create new drug database to facilitate repurposing of drugs

Study explores the effectiveness of a natural protein against colon cancer cells

Study explores the effectiveness of a natural protein against colon cancer cells

Medicines Discovery Catapult relaunches Wolfson Radiochemistry facility in Manchester

Medicines Discovery Catapult relaunches Wolfson Radiochemistry facility in Manchester

Study highlights novel approach for designing anti-viral drugs

Study highlights novel approach for designing anti-viral drugs

Next generation automation lab achieves huge productivity gains

Next generation automation lab achieves huge productivity gains

Researchers develop a cost-effective and versatile approach for drug synthesis

Researchers develop a cost-effective and versatile approach for drug synthesis

Already characterized active substances exhibit unexpected effects

Already characterized active substances exhibit unexpected effects

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

Researchers develop novel technique to control tiny water droplets in lab-on-a-chip applications

Researchers develop novel technique to control tiny water droplets in lab-on-a-chip applications

Deep machine learning adds to the knowledge of one million molecules’ bioactivity

Deep machine learning adds to the knowledge of one million molecules’ bioactivity

WEHI partners with Boehringer Ingelheim to develop novel anti-cancer therapeutics

WEHI partners with Boehringer Ingelheim to develop novel anti-cancer therapeutics

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

New process reinvigorates the search for natural drugs to treat cancers

New process reinvigorates the search for natural drugs to treat cancers

Researchers discover dramatic changes in the chemistry and composition of Sargassum

Researchers discover dramatic changes in the chemistry and composition of Sargassum