Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Scientists identify the sensor in human lungs that detects SARS-CoV-2

Scientists identify the sensor in human lungs that detects SARS-CoV-2

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

Kobe University and Sysmex conduct joint research on new blood test for identifying COVID-19

Kobe University and Sysmex conduct joint research on new blood test for identifying COVID-19

Scientists discover new class of compounds for combating antimicrobial resistance

Scientists discover new class of compounds for combating antimicrobial resistance

Researchers report a potential cancer drug that targets mitochondrial function

Researchers report a potential cancer drug that targets mitochondrial function

Autobahn Labs announces strategic drug discovery collaboration with UCSF

Autobahn Labs announces strategic drug discovery collaboration with UCSF

Researchers create 3D miniature organs that precisely mimic human tissues

Researchers create 3D miniature organs that precisely mimic human tissues

Using genetic engineering to grow synthetic livers

Using genetic engineering to grow synthetic livers

Specific cellular pathways in the fetal gut may reactivate Crohn’s Disease

Specific cellular pathways in the fetal gut may reactivate Crohn’s Disease

Study shows fluorescent protein molecules act as tiny antennas with optical properties

Study shows fluorescent protein molecules act as tiny antennas with optical properties

New breakthrough in AI system could significantly accelerate biological research

New breakthrough in AI system could significantly accelerate biological research

Study shows how drug-like small molecules regulate the activity of ion channels

Study shows how drug-like small molecules regulate the activity of ion channels

Researchers look for mechanisms that stabilize or destabilize key sections of biomolecules

Researchers look for mechanisms that stabilize or destabilize key sections of biomolecules

Tau protein in Alzheimer's disease looks different at every dementia stage

Tau protein in Alzheimer's disease looks different at every dementia stage

Interpretable machine learning models create new options for drug discovery

Interpretable machine learning models create new options for drug discovery

Gold nanoparticles put spotlight on small drug molecules in live cells

Gold nanoparticles put spotlight on small drug molecules in live cells

Research projects receive BTCA awards to develop new drugs

Research projects receive BTCA awards to develop new drugs

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Novel machine learning algorithm helps identify binding sites in drug targets

Novel machine learning algorithm helps identify binding sites in drug targets

New collaboration to develop machine learning methods for chemical discovery

New collaboration to develop machine learning methods for chemical discovery