Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Identification of a bivalent histone-mark switch essential for angiogenesis

Identification of a bivalent histone-mark switch essential for angiogenesis

San Antonio researchers report a new mechanistic target for leukemia drug development

San Antonio researchers report a new mechanistic target for leukemia drug development

Scientists discover families of proteins that could predict organ transplant rejection

Scientists discover families of proteins that could predict organ transplant rejection

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

Culturing marine sponge cells in 3D could scale-up production of biomass, bioactive metabolites

Culturing marine sponge cells in 3D could scale-up production of biomass, bioactive metabolites

Producing New Antibiotics Through Gene Editing

Producing New Antibiotics Through Gene Editing

Evaporators assist academic drug discovery

Evaporators assist academic drug discovery

Experts develop CRISPR-Cas9-mediated inheritance control in male mice

Experts develop CRISPR-Cas9-mediated inheritance control in male mice

Experts develop AI-based binding site detection in nucleic acid macromolecules

Experts develop AI-based binding site detection in nucleic acid macromolecules

TetraScience announces 300% ARR growth and 2021 achievements; prepares for next phase of growth

TetraScience announces 300% ARR growth and 2021 achievements; prepares for next phase of growth

Pyroptosis is not a one-way ticket, it can be halted and controlled

Pyroptosis is not a one-way ticket, it can be halted and controlled

NeoCura and PhoreMost Announce Research Collaboration   to Explore Novel Cancer Therapeutics

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

Research analyzes horizontal gene transfer between viruses and eukaryotes

Research analyzes horizontal gene transfer between viruses and eukaryotes

PhoreMost and POLARISqb announce a multi-target collaboration to investigate next-generation cancer therapies

PhoreMost and POLARISqb announce a multi-target collaboration to investigate next-generation cancer therapies

Cryobioprinting uses a bioink embedded with cells to print frozen and complex structures

Cryobioprinting uses a bioink embedded with cells to print frozen and complex structures

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

New computational method could help quickly screen billions of drug compounds

New computational method could help quickly screen billions of drug compounds

Developing Sperm Cells from Primate Stem Cells

Developing Sperm Cells from Primate Stem Cells

Study finding helps better comprehend necroptosis for treating diseases

Study finding helps better comprehend necroptosis for treating diseases

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment