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Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

Study examines the role of dietary vitamin A in preventing or treating AAP

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

16 Mar 2023

Effective backup mechanism ensures efficient antimicrobial responses in humans

In the human body, virus particles are identified by pattern recognition receptors (PRRs) either within or on the cell surface. When a receptor is activated, a signaling cascade is initiated, which results in the production and release of signaling molecules like interferons and cytokines.

14 Mar 2023

Novel technology easily detects active Mycobacterium tuberculosis infection antibodies

A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.

14 Mar 2023

New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections. Researchers have now discovered that a new class of oral drugs that acts directly on human cells can inhibit a diverse range of pathogenic SARS-CoV-2 strains.

13 Mar 2023

The mechanism behind fruit fly germ cells forming ring canals

Cell division is the process through which the majority of cells in the bodies of living beings duplicate their contents and physically split into new cells.

10 Mar 2023

An alternative option to treat ADCY5-related dyskinesia in patients

The asthma medication theophylline can be used to treat the movement disorder ADCY5-related dyskinesia. A recent study conducted by Martin Luther University Halle-Wittenberg (MLU), University Medicine Halle, and the University of Leipzig Medical Center demonstrated this.

7 Mar 2023

Effective and faster methodology detects RNA viruses based on the triplex-forming probe technology

Experts from the University of Barcelona, the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), the Institute of Microelectronics of Barcelona (IMB-CNM-CSIC) and the Aragon Nanoscience and Materials Institute of Aragon (INMA) -;a joint institute of the CSIC and the University of Zaragoza-; have developed a new method to detect RNA viruses based on the triplex-forming probe technology.

28 Feb 2023

Study reveals why the FMO5 gene produces an enzyme with a different activity

Our body produces lots of enzymes that break down toxic substances. One class of such enzymes are the flavin-containing monooxygenases (FMOs), which are present in all tetrapods. Humans have five different FMO genes, of which the first four display the same activity. However, the fifth FMO gene triggers a different breakdown reaction. University of Groningen biochemists have succeeded in resurrecting the ancestral genes of all tetrapod FMOs to show how this divergence has occurred. Their results appear on 24 February in Nature Communications.

28 Feb 2023

Study shows why a specific gene mutation has opposite effects on mice and human cancers

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

27 Feb 2023

Artificial intelligence creates proteins to hasten chemical reactions

Scientists have for the first time utilized machine learning to design whole new enzymes, which are proteins that quicken chemical reactions. In the realm of protein design, this is a crucial development since new enzymes can find several applications in both industrial manufacture and medicine.

23 Feb 2023

Metabolic reactions upon activating Akt2 enzyme revealed

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2.

22 Feb 2023

Study reveals how chloroplast ATP synthase regulates ATP production in organisms

ATP, the compound essential for the functioning of photosynthetic organisms such as plants, algae, and cyanobacteria, is produced by an enzyme called "chloroplast ATP synthase" (CFoCF1).

22 Feb 2023

New host protease determinants facilitating the infection of SARS-CoV-2 identified

Researchers from Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified novel host protease determinants, that facilitate the infection of SARS-CoV-2, including the Omicron variant, which provided new targets for combating the pandemic.

22 Feb 2023

New technique uses amino acids to cure meat and poultry products

Imagine your favorite cured meat like beef jerky, pepperoni or bacon without any added sodium nitrite from any source currently necessary for color and shelf life. Wes Osburn, Ph.D., is doing exactly that.

22 Feb 2023

New approach to better target cellular proteins

By studying how enzymes move from one membrane compartment to another inside a cell, scientists at the University of Illinois Chicago have figured out a way to better target cellular proteins, which play a role in many diseases.

16 Feb 2023

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

The University of Texas MD Anderson Cancer Center and Replay today announced the launch of Syena, a new oncology-focused product company pioneering T cell receptor (TCR) natural killer (NK) cell therapies.

15 Feb 2023

Versatile molecular toolbox expands the scope of gene regulation

Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.

15 Feb 2023

Researchers discover target enzyme for blast disease

A fungus that plagues rice crops worldwide gains entry to plant cells in a way that leaves it vulnerable to simple chemical blockers, a discovery that could lead to new fungicides to reduce the substantial annual losses of rice and other valuable cereals.

14 Feb 2023

BlueRemediomics aims to synergize marine microbiome data and biobank resources from across Europe

The European Commission has funded the BlueRemediomics project, which will develop novel tools and approaches to cataloguing marine microbiome data and marine culture collections.

13 Feb 2023

Enzyme News and Research

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Study examines the role of dietary vitamin A in preventing or treating AAP

Effective backup mechanism ensures efficient antimicrobial responses in humans

Novel technology easily detects active Mycobacterium tuberculosis infection antibodies

New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

The mechanism behind fruit fly germ cells forming ring canals

An alternative option to treat ADCY5-related dyskinesia in patients

Effective and faster methodology detects RNA viruses based on the triplex-forming probe technology

Study reveals why the FMO5 gene produces an enzyme with a different activity

Study shows why a specific gene mutation has opposite effects on mice and human cancers

Artificial intelligence creates proteins to hasten chemical reactions

Metabolic reactions upon activating Akt2 enzyme revealed

Study reveals how chloroplast ATP synthase regulates ATP production in organisms

New host protease determinants facilitating the infection of SARS-CoV-2 identified

New technique uses amino acids to cure meat and poultry products

New approach to better target cellular proteins

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

Versatile molecular toolbox expands the scope of gene regulation

Researchers discover target enzyme for blast disease

BlueRemediomics aims to synergize marine microbiome data and biobank resources from across Europe

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