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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Genomic Deletions Drive Development of Melanoma Drug Resistance

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

15 Apr 2024

Study Offers Valuable Insights Into Mutagenesis Mechanisms and Cancer Evolution

Mutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organism grows and ages.

13 Apr 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

13 Apr 2024

Meta-Analysis of ABA-Related Stress Responses Reveals Novel Gene Targets in Thale Cress

Plants can be temperamental. Even weeds along the side of highways or pushing their way up in the cracks of concrete sidewalks can get stressed out by dehydration, cold, excess salt and more.

13 Apr 2024

Study Reveals Genetic Underpinnings for Cervical Cancer Risk from Persistent HPV Infections

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.

12 Apr 2024

Cellular Insights Into Facial Morphogenesis

Mother Nature is an artist, but her craft of creating animal faces requires more than a paintbrush and palette. Such highly complex shapes originate from their respective transient neural crest cells.

12 Apr 2024

Understanding Prostate Cancer Disparities Through Proteogenomics

Certain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated with higher risk of metastasis and/or recurrence of the disease, according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2024, held April 5-10.

10 Apr 2024

Bio-Techne Surpasses 10,000 Peer-Reviewed Publications Citing RNAscope Technology

Bio-Techne Corporation today announced that Advanced Cell Diagnostics (ACD), part of Bio-Techne's Spatial Biology Division, has surpassed 10,000 peer-reviewed publications referencing the use and application of RNAscope™ ISH technology.

From Bio-Techne 10 Apr 2024

Precision Combination Therapy Better Controls High-Risk Subtypes of B-ALL in Mouse Models

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

9 Apr 2024

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

9 Apr 2024

AI Predicts Mutations for Improved Protein Function

To design proteins with beneficial functions, researchers typically start with a natural protein possessing a desirable function, such as emitting fluorescent light.

5 Apr 2024

Gut Microbiota Signatures Linked to KRAS Mutations in Colorectal Cancer Patients

For about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those mutations have been linked to shorter survival and more aggressive forms of disease.

5 Apr 2024

Breakthrough Study Reveals Genetic Variants with Significant Impact on Obesity Risk

A study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date.

5 Apr 2024

New Platform Reveals Individual Sensitivity to Disease-Causing Mutations

In humans, the exact same mutation in a specific gene can produce widely different outcomes. It's a bit like adding the same amount of salt to different recipes-;the effect on the finished dish can be quite different, depending on the mix of other ingredients.

4 Apr 2024

Researchers Uncover the FACT-ETS-1 Antiviral Response Pathway

By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide variety of viruses.

4 Apr 2024

SARS-CoV-2 Variants Detected in Flood-Control Channels Near Homeless Encampments

To better understand COVID-19's spread during the pandemic, public health officials expanded wastewater surveillance.

4 Apr 2024

New Tool Predicts How Proteins Interact with RNA Structures

Scientists at the Italian Institute of Technology and Aarhus University have figured out how specific proteins can bind to G-quadruplexes, which are unique RNA structures.

4 Apr 2024

Rare YKT6 Gene Variants Linked to New Neurological Disorder

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

2 Apr 2024

Eleven New Trichoderma Species Discovered in Chinese Soil and Plant Samples

Trichoderma spp. are globally distributed and are considered significant fungal resources. They are widely studied and applied due to their economic and ecological importance, offering numerous benefits, such as producing enzymes and antibiotics, aiding in plant growth, and protecting them from pathogens.

2 Apr 2024

Gene News and Research

Further Reading

Genomic Deletions Drive Development of Melanoma Drug Resistance

Study Offers Valuable Insights Into Mutagenesis Mechanisms and Cancer Evolution

How Glucocorticoids Quell Inflammation

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

Meta-Analysis of ABA-Related Stress Responses Reveals Novel Gene Targets in Thale Cress

Study Reveals Genetic Underpinnings for Cervical Cancer Risk from Persistent HPV Infections

Cellular Insights Into Facial Morphogenesis

Understanding Prostate Cancer Disparities Through Proteogenomics

Bio-Techne Surpasses 10,000 Peer-Reviewed Publications Citing RNAscope Technology

Precision Combination Therapy Better Controls High-Risk Subtypes of B-ALL in Mouse Models

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

AI Predicts Mutations for Improved Protein Function

Gut Microbiota Signatures Linked to KRAS Mutations in Colorectal Cancer Patients

Breakthrough Study Reveals Genetic Variants with Significant Impact on Obesity Risk

New Platform Reveals Individual Sensitivity to Disease-Causing Mutations

Researchers Uncover the FACT-ETS-1 Antiviral Response Pathway

SARS-CoV-2 Variants Detected in Flood-Control Channels Near Homeless Encampments

New Tool Predicts How Proteins Interact with RNA Structures

Rare YKT6 Gene Variants Linked to New Neurological Disorder

Eleven New Trichoderma Species Discovered in Chinese Soil and Plant Samples

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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