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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

31 Mar 2023

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

Single monoclonal antibody infusion can strengthen the body's fight against yellow fever

New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.

30 Mar 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

SARS-CoV-2 infection hijacks and damages parts of infected cells' vital RNA machinery

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

30 Mar 2023

Study expands understanding of PAK1-related IDDMSSD

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

30 Mar 2023

New nanoparticles can perform gene editing in the lungs, paving the way for inhalable therapies

Nanoparticles can be used to deliver messenger RNA encoding proteins to the lungs, results of a new study carried out at MIT and the University of Massachusetts Medical School show.

From Massachusetts Institute of Technology (MIT) 30 Mar 2023

Genetic welding: Evolutionary meddling with genes

With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations.

29 Mar 2023

Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

29 Mar 2023

Evolution driven by genetic engineering should be known as ‘genetic welding’ to draw scientific and ethical scrutiny

In an opinion paper, evolutionary geneticist Asher Cutter highlights the importance of coining the term ‘genetic welding’ for the anthropogenic manipulation of genetic drive made possible by tools such as CRISPR-Cas9.

29 Mar 2023

Analyzing the GmZF351 transgenic soybean plants and their stress tolerance

Across the globe, soybean is considered to be an important food, oil, and feed crop worldwide.

29 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Determining cell differentiation trajectories has been done by genes and the regulation relationships among them creating complicated networks.

28 Mar 2023

Resistance genes in human gut influenced by national trends in antibiotic consumption

According to a new study performed at the Earlham Institute and Quadram Institute in Norwich, the community of microbes living in and on human bodies might be serving as a reservoir for antibiotic resistance.

28 Mar 2023

Investigating methanogens to unravel the genetics of temperature adaptation

The history of the Earth has been one of physical extremes-;extreme atmospheric conditions, extreme chemical environments, and extreme temperatures.

28 Mar 2023

Machine learning reveals the complexities of difficulties in designer chromosome synthesis

Artificially synthesizing genomes has several applications, including medical research and industrial strains.

28 Mar 2023

High-quality genome of a deep-sea eel illuminates the molecular mechanisms of deep-sea adaptation

Recently, the research team led by Dr. Shunping He from the Institute of Deep Sea Science and Engineering, Chinese Academy of Sciences, published their research findings in the online version of SCIENCE CHINA Life Sciences.

28 Mar 2023

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

A new research paper was published in Genes & Cancer on March 10, 2023, entitled, "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer."

27 Mar 2023

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut.

27 Mar 2023

No more needles? Future vaccines could be delivered by a puff of air

In the future, vaccines may be delivered with a puff of air rather than a needle, according to the promising results of new research presented at a meeting of the American Chemistry Society this March.

27 Mar 2023

Gene News and Research

Further Reading

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Single monoclonal antibody infusion can strengthen the body's fight against yellow fever

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

SARS-CoV-2 infection hijacks and damages parts of infected cells' vital RNA machinery

Study expands understanding of PAK1-related IDDMSSD

New nanoparticles can perform gene editing in the lungs, paving the way for inhalable therapies

Genetic welding: Evolutionary meddling with genes

Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

Evolution driven by genetic engineering should be known as ‘genetic welding’ to draw scientific and ethical scrutiny

Analyzing the GmZF351 transgenic soybean plants and their stress tolerance

The proper implementation of stem cell-based disease models

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Resistance genes in human gut influenced by national trends in antibiotic consumption

Investigating methanogens to unravel the genetics of temperature adaptation

Machine learning reveals the complexities of difficulties in designer chromosome synthesis

High-quality genome of a deep-sea eel illuminates the molecular mechanisms of deep-sea adaptation

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

No more needles? Future vaccines could be delivered by a puff of air

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