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How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

Leveraging the Materiobiology Approach to Design Biomaterials for Aged Bone Repair

In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities, including a reduction in the self-renewal and differentiation abilities of mesenchymal stem cells, an excessive accumulation of inflammatory signals, compromised blood vessel regeneration capacity, an imbalance between bone anabolism and catabolism, and inadequate bone innervation.

13 Apr 2024

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

13 Apr 2024

Meta-Analysis of ABA-Related Stress Responses Reveals Novel Gene Targets in Thale Cress

Plants can be temperamental. Even weeds along the side of highways or pushing their way up in the cracks of concrete sidewalks can get stressed out by dehydration, cold, excess salt and more.

13 Apr 2024

Study Reveals Genetic Underpinnings for Cervical Cancer Risk from Persistent HPV Infections

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.

12 Apr 2024

Understanding Prostate Cancer Disparities Through Proteogenomics

Certain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated with higher risk of metastasis and/or recurrence of the disease, according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2024, held April 5-10.

10 Apr 2024

Precision Combination Therapy Better Controls High-Risk Subtypes of B-ALL in Mouse Models

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

9 Apr 2024

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

9 Apr 2024

RNA Molecules Govern Battle Between Cholera Bacteria and Phages

Viruses need hosts. Whether it's measles, the flu or coronavirus, viral pathogens cannot multiply or infect other organisms without the assistance of their hosts' cellular infrastructure.

5 Apr 2024

Breakthrough Study Reveals Genetic Variants with Significant Impact on Obesity Risk

A study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date.

5 Apr 2024

Researchers Uncover the FACT-ETS-1 Antiviral Response Pathway

By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide variety of viruses.

4 Apr 2024

Genetic Analysis Unveils Underlying Causes of Chronic Kidney Disease

Chronic kidney disease (CKD) is extremely prevalent among adults, affecting over 800 million individuals worldwide.

4 Apr 2024

Engineering Bacteria to Grow Self-Dyeing Vegan Leather

Scientists at Imperial College London have modified bacteria genetically to produce leather that is free from animal products and plastic and has the ability to dye itself.

4 Apr 2024

Warwick researchers discover giant phage with potential as a treatment for lung infections

Scientists have found a new bacteria-fighting agent that can attack a common lung infection caused by Burkholderia bacteria.

4 Apr 2024

Study Reveals Early Development of Circadian Rhythms in Infant Gut Microbiomes

Infant gut microbiomes oscillate with a circadian rhythm, even when they are cultivated outside of the body.

3 Apr 2024

Unveiling the Hidden Lives of Microbes Deep Underground

A group of scientists working at Bigelow Laboratory for Ocean Sciences have created a novel technique that connects the genetics and functionality of individual microbes that are oxygen-free and exist far below the surface of the Earth.

3 Apr 2024

High-Resolution Map Tracks Cellular Changes During Inflammation

Cells within the intestines fulfill diverse functions, including nutrient absorption, sensing, and regulating homeostasis. Gut inflammation is a characteristic that sets certain chronic disorders apart.

3 Apr 2024

New Research Rewrites Bird Family History

An immense meteor spelled doom for most dinosaurs 65 million years ago. However, not all perished. In the aftermath of the extinction event, birds—technically dinosaurs themselves—prospered.

2 Apr 2024

Study Investigates Links Between Gene Expression and Primate Brain Evolution

An interdisciplinary team of researchers led by biologists at the University of Massachusetts Amherst recently published the results of a first-of-its-kind study investigating the links between gene expression and brain evolution across 18 primate species.

1 Apr 2024

Study Reveals Insights into Evolution of Regulatory Proteins

New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression.

1 Apr 2024

Genes News and Research

How Glucocorticoids Quell Inflammation

Leveraging the Materiobiology Approach to Design Biomaterials for Aged Bone Repair

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

Meta-Analysis of ABA-Related Stress Responses Reveals Novel Gene Targets in Thale Cress

Study Reveals Genetic Underpinnings for Cervical Cancer Risk from Persistent HPV Infections

Understanding Prostate Cancer Disparities Through Proteogenomics

Precision Combination Therapy Better Controls High-Risk Subtypes of B-ALL in Mouse Models

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

RNA Molecules Govern Battle Between Cholera Bacteria and Phages

Breakthrough Study Reveals Genetic Variants with Significant Impact on Obesity Risk

Researchers Uncover the FACT-ETS-1 Antiviral Response Pathway

Genetic Analysis Unveils Underlying Causes of Chronic Kidney Disease

Engineering Bacteria to Grow Self-Dyeing Vegan Leather

Warwick researchers discover giant phage with potential as a treatment for lung infections

Study Reveals Early Development of Circadian Rhythms in Infant Gut Microbiomes

Unveiling the Hidden Lives of Microbes Deep Underground

High-Resolution Map Tracks Cellular Changes During Inflammation

New Research Rewrites Bird Family History

Study Investigates Links Between Gene Expression and Primate Brain Evolution

Study Reveals Insights into Evolution of Regulatory Proteins

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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