Genetic Engineering News and Research

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Scientists fine-tune plasma treatment to optimize plant growth and yield

Ever since scientists discovered that plasma treatment leads to faster growth and higher yields of some agricultural crops, physicists, chemists, and biologists have been working together to tease out the mechanisms driving this phenomenon.

7 Oct 2020

Gene therapy overcomes cardiac effects in mouse model of Freidreich’s ataxia

Gene therapy was successfully used to overcome the cardiac effects of Freidreich’s ataxia (FA) in a mouse model of the disease, as reported in the peer-reviewed journal Human Gene Therapy. Click here to read the full-text article free online through October 18, 2020.

21 Sep 2020

SMART researchers discover a novel method to produce human red blood cells

Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have discovered a new way to manufacture human red blood cells (RBCs) that cuts the culture time by half compared to existing methods and uses novel sorting and purification methods that are faster, more precise and less costly.

15 Sep 2020

Regulating cancer stemness using combination of nanotechnology and genetic engineering

The development of chemotherapeutic agents with selective anti-cancer activities is increasingly unattractive due to the emergence of resistance, poor targeting of cancer tissues, and subsequent metastasis.

18 Aug 2020

Using genetic engineering to study evolutionary assimilation of foreign DNA in a new host

All life is subject to evolution in the form of mutations that change the DNA sequence of an organism's offspring, after which natural selection allows the 'fittest' mutants to survive and pass on their genes to future generations.

11 Aug 2020

Gene therapy to the inner retina prevents blindness in Cln3-deficient mice

Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease.

11 Aug 2020

Researchers isolate fragile protein complex from heat-loving bacteria

Goethe University scientists have discovered what is probably the oldest enzyme found in cellular respiration. Now, the team has successfully isolated a highly delicate protein complex known as “Rnf” from the heat-loving bacterium called Thermotoga maritima.

10 Aug 2020

Discovery Could Lead To More Potent Garlic, Boosting Flavor And Bad Breath

For centuries, people around the world have used garlic as a spice, natural remedy, and pest deterrent, but they did not know how powerful garlic was.

6 Aug 2020

Researchers develop CAR-T cell therapy based on TCR signal transduction

The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

4 Aug 2020

Study reveals efficient expression system for production of coagulation factor XIIIa

Many reports illustrate that Coagulation factor XIIIa (FXIIIa) has diverse and crucial functions in thrombus for¬mation and stability.

29 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Hypercompact CRISPR enzyme from bacteriophages expands genome editing toolbox

A recently discovered hypercompact CRISPR enzyme found only in huge bacteriophages, and known as CRISPR-CasΦ, is functional, a new study by Patrick Pausch, Jennifer Doudna and colleagues reports, and it provides a powerful new tool in the CRISPR genome editing toolbox, including because it can target a wider range of genetic sequences compared to Cas9 and Cas12

17 Jul 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

Genomic research can help combat COVID-19

Next-generation sequencing of the COVID-19 virus is providing powerful metagenomic data, which, combined with clinical data, will inform the search for effective treatments, as reported in the peer-reviewed journal Pediatric Allergy, Immunology, and Pulmonology.

5 Jun 2020

New technique restores hearing in mice with a recessive genetic mutation

Using a new genetic engineering technique, known as base editing, researchers from Boston Children's Hospital and the Broad Institute of MIT and Harvard, have restored hearing in mice with a known recessive genetic mutation.

5 Jun 2020

Recombineering technique may overcome barriers in bacterial engineering

Genetic engineering of bacteria has transformed contemporary medicine, from bacterial-based insulin to a deeper insight into infectious diseases.

From Harvard Medical School 1 Jun 2020

Using light to control the viability and mobility of individual cells

Photopharmacology is the study that examines the use of light to change the impact of drugs on and off. For the first time, researchers from Jena, Munich, and New York have successfully applied this technique to regulate a component of cells that was earlier believed to be inaccessible.

18 May 2020