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Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

16 Aug 2022

Giving attention to beta cells instead of the immune system could be a chance to prevent type 1 diabetes

Research studying the autoimmune response, in which the immune system kills the insulin-producing pancreatic islet beta cells, is a common topic of type 1 diabetes research.

1 Jul 2022

How rice breeders develop a new low glycemic index, high protein rice

Some perceive rice as a "bad" source of carbohydrates. That's because most varieties of rice have a high glycemic index.

24 Jun 2022

Researchers demonstrate a possible new way of generating insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.

14 Jun 2022

New technique uses genetic data that may better predict disease risk in a population

Polygenic risk scores (PRS) are promising tools for forecasting disease risk, but current versions have bias built-in, which can reduce their accuracy in some populations and lead to health disparities.

10 May 2022

New protective mechanism against non-alcoholic fatty liver disease identified

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Research associates autophagy and age-related nervous system degradation

The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.

20 Apr 2022

Researchers create RNA molecules to address human pancreatic beta cells

Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.

11 Apr 2022

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

Powerhouse-pruning protein may be a sound target to help trigger new blood vessel growth

A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.

5 Apr 2022

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice.

31 Mar 2022

Nanotranslator enables communication between two different living microorganisms

Cells communicate with one another in the language of chemistry, but those from different kingdoms, such as bacteria and yeast, speak dialects virtually unintelligible to the other.

17 Mar 2022

Experts provide novel insights into complex sugar metabolism

The accurate mechanism of action of a β-1,2-glucan-associated enzyme has been determined by Japanese researchers.

From Tokyo University of Science 8 Mar 2022

Novel ways to increase SC-beta cell’s survivability and functioning via genetic manipulation

New advancements in the transplantation of stem cell-derived insulin-producing beta cells to cure type 1 diabetes have created substantial curiosity.

7 Mar 2022

UTSA team develops innovative inhibitor to fight obesity and heart disease

An interdisciplinary research team at The University of Texas at San Antonio has successfully developed an innovative inhibitor that shows promise in fighting obesity and potentially preventing heart disease.

4 Mar 2022

Researchers discover how pancreatic cells remodel themselves to reduce the immune response in patients at risk for T1D

Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.

2 Mar 2022

In vivo tracking of unlabeled stem cells using sugars

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers -; made out of sugars -; that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Flavanols enhance browning of adipose tissue by activating the sympathetic nervous system

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria-;subcellular organelles associated with energy production-;which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

3 Feb 2022

Researchers produce ovalbumin with the help of ascomycete fungus

The Future Sustainable Food Systems research group found that fungus-produced ovalbumin can reduce the environmental impact of chicken egg white powder.

11 Jan 2022