Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Mysterious protein clusters found on neurons are calcium-signaling “hotspots”, study reveals

For 30 years, mysterious clusters of proteins found on the cell body of neurons in the hippocampus, a part of the brain, both intrigued and baffled James Trimmer.

From The University of California, Davis 15 Nov 2021

New insights into the role of fat cells in cognitive decline and neurodegeneration

Findings published this week reveal new insights into the role of fat cells in cognitive decline and neurodegeneration, according to a study that involves the oxidant amplification loop led by Marshall University scientists.

22 Oct 2021

Researchers discover that existing drug can enhance memory

A group of scientists identified that a prevailing drug for treating constipation might boost an individual’s capability to think with better clarity.

4 Oct 2021

UMSOM study suggests a genetic basis behind instantaneous human compatibility

Have you ever met someone you instantly liked, or at other times, someone who you knew immediately that you did not want to be friends with, although you did not know why?

2 Sep 2021

Study reveals how 3D space is represented in the mammalian cortex by the brain's 'GPS'

In a new study published in Nature today, Weizmann Institute of Science researchers, in collaboration with colleagues from the Hebrew University of Jerusalem, unveiled for the first time how three-dimensional space is represented in the mammalian cortex by the brain's "GPS" system.

13 Aug 2021

Study discovers link between corticosteroid receptors and hippocampal neuroplasticity, ciliary genes

Chronic stress is a well-known cause for mental health disorders. New research has moved a step forward in understanding how glucocorticoid hormones ('stress hormones') act upon the brain and what their function is.

9 Aug 2021

Making memories necessitates a lot of DNA breakage

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

7 Jul 2021

Study reveals the first look of brains retrieving faulty memories

Scientists have observed for the first time what it looks like in the key memory region of the brain when a mistake is made during a memory trial.

9 Jun 2021

Study shows why “the brain's memory center” is vulnerable to damage, degeneration

In a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for why the area, commonly referred to as 'the brain's memory center', is vulnerable to damage and degeneration, a precursor to Alzheimer's disease.

31 May 2021

Researchers gain new insights into the physiological functions of APP protein

The pivotal role played by the APP protein in Alzheimer’s disease is well known.

20 May 2021

Study shows that neural stem cells age quickly

A research team has revealed that neural stem cells (NSCs)—that is, the stem cells of the nervous system—age quickly.

14 Apr 2021

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

A genetic engineering approach has helped scientists to drastically decrease the levels of tau protein.

22 Mar 2021

Two new Alzheimer’s genes discovered

AZoLifeSciences speaks to researchers from Tianjin Medical University about their latest research that led to the discovery of two new genes that are linked to Alzheimer's disease.

From Tianjin Medical University 1 Mar 2021

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

From UC San Diego 19 Feb 2021

Regular caffeine intake can change gray matter of the brain

Coffee, cola, or an energy drink: caffeine is the world's most widely consumed psychoactive substance. Researchers from the University of Basel have now shown in a study that regular caffeine intake can change the gray matter of the brain. However, the effect appears to be temporary.

17 Feb 2021

KAIST researchers identify mechanism underlying plasticity in adult brains

Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away.

28 Dec 2020

Hippocampus News and Research

Mysterious protein clusters found on neurons are calcium-signaling “hotspots”, study reveals

New insights into the role of fat cells in cognitive decline and neurodegeneration

Researchers discover that existing drug can enhance memory

UMSOM study suggests a genetic basis behind instantaneous human compatibility

Study reveals how 3D space is represented in the mammalian cortex by the brain's 'GPS'

Study discovers link between corticosteroid receptors and hippocampal neuroplasticity, ciliary genes

Making memories necessitates a lot of DNA breakage

Study reveals the first look of brains retrieving faulty memories

Study shows why “the brain's memory center” is vulnerable to damage, degeneration

Researchers gain new insights into the physiological functions of APP protein

Study shows that neural stem cells age quickly

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

Two new Alzheimer’s genes discovered

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Regular caffeine intake can change gray matter of the brain

KAIST researchers identify mechanism underlying plasticity in adult brains

Study sheds light on molecular underpinnings of long-term memory

Polβ enzyme prevents breakdown of DNA in the hippocampus region

Researchers identify brain protein that leads to seizures, abnormal social behaviors

Disrupted brain remapping causes spatial memory impairment in Alzheimer's

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