Immune Response News and Research

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Reawakened Endogenous Retroviruses can Play a Critical Role in Helping Cancer Survive

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago.

18 Jul 2024

Unveiling IRF1's Influence on Cancer Progression and Treatment Using Histology and Flow Cytometry

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have discovered new information regarding the function of a protein known as interferon regulatory factor (IRF1) in the course of cancer and how it responds to treatment. This information may help increase the efficacy of cancer immunotherapy.

16 Jul 2024

Marginal Zone B Cells Unveiled as Key Players in TB Vaccine Strategy

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

16 Jul 2024

Harnessing Immune Cell Triads for Effective Cancer Treatment

There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully -; completely eliminating or greatly reducing cancer in particular patients -; other times they don't work at all. It's a mystery.

16 Jul 2024

UQ Researchers Reveal Mechanism of Immune Evasion by Haemophilus influenzae

Researchers from The University of Queensland have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness.

12 Jul 2024

Liver Blood Vessels Trigger 'Sleep Timer' to Inactivate Immune Cells in Chronic Hepatitis B

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive.

11 Jul 2024

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Unveiling Progesterone's Impact on Cancer Immunosuppression

Researchers turned to pregnancy to explore why some cancers successfully evade the immune system and grow unchecked.

9 Jul 2024

Scientists develop first fully functional human immune system in mouse model

Researchers at The University of Texas Health Science Center in San Antonio have produced a mouse model that is humanized, complete with a human immune system and a gut microbiome that resembles that of a human being and is able to elicit particular antibody responses.

8 Jul 2024

Wild Chimpanzees Found to Consume Medicinal Plants to Combat Illness

Researchers from Africa and Europe observed habituated chimpanzee communities to understand this potentially self-medicating behavior.

26 Jun 2024

Ultrasound-Triggered Nanodroplets for Targeted Drug Delivery

Conventional drug delivery is often like cracking a nut with a sledgehammer. Whether the drug is swallowed, injected, inhaled, or absorbed through the skin, it ultimately diffuses to most parts of the body, including those where it isn’t needed – or where it even might cause harm.

22 Jun 2024

Study Reveals Immune Factors Behind COVID-19 Resistance in Some Individuals

As part of the first-ever COVID-19 human challenge study, researchers from the Wellcome Sanger Institute, University College London (UCL), Imperial College London, the Netherlands Cancer Institute, and their collaborators examined immune responses against SARS-CoV-2 infection in healthy adult volunteers using single-cell sequencing.

20 Jun 2024

Johns Hopkins Scientists Engineer Synthetic Cells to Mimic Symmetry Breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

14 Jun 2024

Exploring the Use of Weakened Viruses for Cancer Treatment

Scientists at Northwestern Medicine have found that an attenuated virus can aid in the elimination of cancer in mice. Furthermore, mice given this virus treatment had a higher lifetime tumor-prevention rate.

12 Jun 2024

Epitope Binning-Seq: Revolutionizing Antibody Drug Discovery

Monoclonal antibodies are powerful tools in medicine due to their remarkable ability to target specific sites on antigens (foreign invaders) called epitopes.

11 Jun 2024

Study Unveils Broader Immune Response in EBV-MS Connection

Epstein-Barr virus (EBV) may have a greater effect on the development of multiple sclerosis (MS) than previously believed due to a higher level of cross-reactivity, which occurs when the immune system binds to the incorrect target.

10 Jun 2024

Coordinated Proteins Aid the Immune System in Detecting and Destroying Threats

Bacteria, parasites, and viruses—the immune system tackles them all. Cells known as macrophages are at the forefront of the human immune response, recognizing intruders and controlling how the entire immune system responds.

6 Jun 2024

Exploring Hepatic and Serum Proteomic Signatures in Werner Syndrome Mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

New Trojan Horse Virus Potentially Linked to Severe Toxoplasmosis

An international team led by researchers at the University of Toronto has found a new RNA virus that they believe is hitching a ride with a common human parasite.

3 Jun 2024

New Birnavirus Discovered in Pet Trade Zebrafish

Zebrafish in the pet trade are asymptomatic carriers of previously undescribed microbes, including a novel virus that causes hemorrhaging in infected laboratory fish, Marlen Rice from the University of Utah, US, and colleagues report in the open-access journal PLOS Biology, publishing May 23rd.

31 May 2024