Immunotherapy News and Research

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Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Preventing immune cell reprogramming could be a new way to stop breast cancer metastasis

Natural killer cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape.

10 Jul 2020

Study shows engineered natural killer immune cells can directly kill tumor cells

According to a study, researchers have successfully designed natural killer immune cells that destroy head and neck tumor cells in mice.

8 Jul 2020

Molecular dynamic simulations may contribute to structure-based drug design

Uppsala University scientists have reported that they have developed a new way to predict how unique molecules that can be employed in novel immunotherapy.

26 Jun 2020

Blocking A 'Jamming Signal' Can Unleash Immune System To Fight Tumors

Yale researchers have discovered a "jamming signal" that blocks a powerful immune system stimulant called interleukin-18 (IL-18) from reaching tumors.

25 Jun 2020

CAR T Cell Therapy: Potential For Considerable Savings

CAR T cell therapy is a new and, in some cases, highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system.

24 Jun 2020

Manipulating immune cells could be a viable strategy for treating cancer

Most traditional cancer therapies target either the tumor cells themselves or indiscriminately kill any rapidly dividing cell.

From UC San Diego 23 Jun 2020

Using CAR T cells to target senescence-related diseases

Chimeric antigen receptor (CAR) T cells have transformed the treatment of refractory blood cancers. These genetically engineered immune cells seek out and destroy cancer cells with precision.

19 Jun 2020

Immune system could be 're-trained' to stop attack of healthy cells, study finds

The body's immune system can be re-wired to prevent it from recognizing its own proteins which, when attacked by the body, can cause autoimmune diseases like multiple sclerosis, a significant new study by UK scientists has found.

10 Jun 2020

New technology can help map immune cells in different types of brain tumors

Removing a malignant brain tumor is a balancing act between protecting the healthy tissue and, at the same time, excising as much tumor tissue as possible.

1 Jun 2020

New flow cytometry technique to quantify protein production in T-cells

A team of scientists from Hollings Cancer Center at the Medical University of South Carolina has developed a novel flow cytometry technique that can, for the first-time, quantify protein production in T-cells.

21 May 2020

Direct Control Of Dendritic Cells For Tracking And Immune Modulation

Dendritic cells are one of our bodies' first line of defense and are stationed like sentinels at all surfaces, as well as in most of our organs.

19 May 2020

Blood Cells Could Serve As A 'Thermometer' To Detect Breast Cancer

Immune system cells in the blood of breast cancer patients undergo alterations early in the disease course, according to a study.

18 May 2020

Treating solid cancers using the formation of natural killer-tumor cell immunological synapse

There are immune cells in our bodies that directly destroy infected or cancer cells - they are called natural killer cells. Recently, a POSTECH research team has developed an integrative cancer therapy using adoptive natural killer cell therapy and chemotherapy.

14 May 2020

A New Plant-Based System For The Mass Production Of Allergens For Immunotherapy

Allergen immunotherapy provides long-lasting relief to people suffering from allergies, but the therapy can last years and requires large amounts of allergen.

13 May 2020

The microbiome regulates our immune system's fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité - Universitätsmedizin Berlin, the Berlin Institute of Health and the German Rheumatism Research Center Berlin were able to show how the microbiome helps to render the immune system capable of responding to pathogens.

13 May 2020

New sampling method can more accurately detect genetic alterations in tumors

A wholistic tumor sampling method that more accurately detects genetic alterations in tumors, which are critical in allowing treatment to be personalized to each and every patient, has been developed by researchers from the Crick, Roche and The Royal Marsden NHS Foundation Trust and published in Cell Reports.

12 May 2020

Selectively eliminating leukemic and hematopoietic stem cells

Acute myeloid leukemia is an aggressive cancer of the blood-forming system. It affects the hematopoietic stem cells, or blood stem cells, of various white blood cells and of the red blood cells and platelets.

11 May 2020

Pancreatic tumors hijack basic cell mechanism for immune evasion

Pancreatic cancer cells use a normal waste removal process to hide tags on their surfaces that would otherwise let the immune system destroy them, a new study finds. Published online April 22 in Nature, the study results help to answer a longstanding question: why are pancreatic cancers so resistant to immunotherapies, which use the body's own immune defenses to fight cancer?

24 Apr 2020

Combination therapy encourages innate immune cells to eat GBM tumors

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020