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Experts describe structure of protein complex vital for proper cell function

Mitochondrial diseases exhibit different symptoms like muscle weakness, severe fatigue, even blindness. Most genetic diseases are the result of mitochondrial defects.

8 Oct 2021

Study explores molecular mechanism behind cell homing

Research reveals how stem cells slow down their rolling inside the circulatory system by developing long tethers that bind to the inner surfaces of blood vessels.

8 Oct 2021

Experts create “living medicine” to combat biofilms on medical implants

Scientists have developed the first “living medicine” to treat antibiotic-resistant bacteria thriving on medical implants’ surfaces.

8 Oct 2021

Researchers reveal how and why cytoquakes occur

Researchers earlier identified that animal cell cytoskeletons rearrange quickly at times, starting an earthquake-like disturbance in the part of the cell.

7 Oct 2021

Researchers use cryo-electron microscopy to resolve 3D structure of protein nanoparticle

Nanoparticles and nanocages are attractive materials that may be applied in color agents, catalysts, and drug delivery.

6 Oct 2021

Researchers identify the mechanism leading to deafness in Norrie disease

A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.

6 Oct 2021

New study reveals lung cell roles in guiding the immune system

Lung immunity is essential to combat all pulmonary diseases, including COVID-19, pneumonia, lung cancer, asthma and COPD.

6 Oct 2021

Researchers record the breaking of a single chemical bond using advanced microscopy techniques

Using advanced microscopy techniques at Princeton University, researchers have recorded the breaking of a single chemical bond between a carbon atom and an iron atom on different molecules.

5 Oct 2021

Findings of a new study likely to help design fluorescent, protein-based sensors

Proteins, the molecular machines, make all living organisms hum. They are capable of healing cells, preventing deadly infections, and more.

4 Oct 2021

New datasets published to better train ML models for drug discovery

Polymorphs are molecules that have different molecular packing arrangements despite identical chemical compositions. In a recent paper, researchers at GlaxoSmithKline (GSK) and the Cambridge Crystallographic Data Centre (CCDC) combined their proprietary (GSK) and published (CCDC) datasets to better train machine learning (ML) models to predict stable polymorphs to use in new drug candidates.

4 Oct 2021

Novel Assay Platform for 3D Microfluidic Cancer Research

AMSBIO have supplied custom Chimeric antigen receptor (CAR)-T products to the University of Strathclyde (UoS) in Glasgow, UK, and ScreenIn3D Ltd, allowing them to perform novel immune-oncology assays in 3D microfluidic cancer models.

From AMS Biotechnology 1 Oct 2021

Experts state muscle-secreted neurturin provides similar results as exercise

Scientists from the Karolinska Institutet pinpointed a protein that enhances motor coordination, muscular metabolism, and exercise performance in mice.

1 Oct 2021

Study unravels factors involved in risiRNA generation

A team of scientists disclosed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism.

1 Oct 2021

Master regulator behind the development of antibody-producing cells identified

Scientists from Weill Cornell Medicine recently found the master regulator behind the development of antibody-creating cells.

27 Sep 2021

Structural parameters of phosphatidylglycerol-DNA complex revealed

An interaction of DNA with lipids is of great interest because of their functions. As fatty acids and lipids can specifically bind to nucleic acids forming a code sequence of the genomic DNA, it is important to study the interaction of the oligonucleotide DNA (dA)20-(dT)20 with phosphatidylglycerol by the molecular dynamics method.

24 Sep 2021

How does the KLF4 transcription factor influence gene expression?

Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.

24 Sep 2021

Novel process for accurate data analysis from NMR spectrometers

Researchers created a process employing machine learning to enhance data examination from a robust scientific tool—nuclear magnetic resonance (NMR).

23 Sep 2021

Potential biomarkers help diagnose progressive stages of liver disease

Results of national research pinpointed potential biomarkers that could ultimately be employed for the diagnosis of progressive stages of liver disease.

23 Sep 2021

Researchers seek to point a way toward a unified theory for DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Researchers find a new way to counter immunosuppressive effect in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

21 Sep 2021