Nucleotide News and Research

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A Novel Technique for Ribonucleotide Quantification

Scientists at the Folkhälsan Research Center have devised a novel technique enabling the straightforward quantification of ribonucleotides in small tissue and cell samples within a standard laboratory setting, without the need for specialized equipment.

28 Nov 2023

New Optical Tweezers Open Up New Insights on Specific DNA Motor Proteins

Using “optical tweezers” driven by lasers, researchers have discovered a universal motor mechanism that viruses utilize to package their DNA into infectious particles.

22 Nov 2023

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Scientists have unraveled the mechanism by which a particular metabolite regulates DNA repair activity and the susceptibility of tissues to cancer treatment.

3 Nov 2023

Bacteriophages as Unexpected Allies in Mammalian Health

In a research study, Jeremy J. Barr, along with colleagues from Monash University in Victoria, Australia, present findings indicating that mammalian cells may uptake phages as a means to enhance cellular growth and survival.

27 Oct 2023

The Agricultural Soil Microbiome: A DNA Metabarcoding Perspective

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24 Oct 2023

DNA-Origami Nanoengine Performing Pulsing Movements

An international team of scientists has just invented a revolutionary form of DNA nano-engine.

20 Oct 2023

Genes may be Responsible for Third of Complex Regional Pain Syndrome Cases

But the condition is less common in men, even though they are more likely to have the 4 genetic variations implicated in heightened risk, suggesting that there may be sex specific causes, say the researchers.

11 Oct 2023

Canine DNA Database Provides Unprecedented Look at Dog Evolution

A global collaboration of scientists is leveraging an exceptionally extensive canine DNA database to conduct an impartial exploration into the evolutionary processes that have given rise to the diverse breeds of our canine companions.

8 Sep 2023

MAGE Technology Helps Reveal the Potency of Antibiotics

By substituting each of the 20 amino acid alternatives found in nature for one of the 38 amino acid components that make up the rifampicin binding site on E. coli, the study authors were able to produce 760 distinct RNAP mutants. The development of this mutant pool was then examined under various circumstances, including rifampicin therapy.

31 Aug 2023

Novel Genotyping Method Reveals New Insights into Lettuce Genomics

A consortium of European investigators used SPET for the first time in lettuce (Lactuca sativa L.) as part of the European Evaluation Network (EVA) of the European Cooperative Programme for Plant Genetic Resources (ECPGR), with the goal of studying its genetic diversity and identifying genomic regions that underpin agronomically important traits.

31 Aug 2023

Analyzing Genome Sequencing of 2,000 Canids by the Dog10K Consortium

More than 2,000 canine genomes have been generated and examined by an international research consortium.

21 Aug 2023

Revealing the Link Between Radiation Damage and DNA Rupture Time

Investigators from the University of Trento’s Physics Department discovered a link between the effect of radiation on DNA and the time when the damaged molecule breaks irreversibly.

9 Aug 2023

Study Identifies a Gene That Largely Controls Weeping Growth in Apple

Plant geneticists have identified a mutation in a gene that causes the "weeping" architecture – branches growing downwards – in apple trees, a finding that could improve orchard fruit production.

21 Jul 2023

EMBL-EBI Launches Pathogens Portal to Enhance Global Pathogen Surveillance

EMBL's European Bioinformatics Institute (EMBL-EBI) has launched the Pathogens Portal – an online platform that enables researchers, clinicians, and policymakers to access the most comprehensive collection of biomolecular data about pathogens.

7 Jul 2023

New Method Provides Near-Perfect Control Over the Manipulation of Individual Molecules

Aleksandra Radenovic, Head of the School of Engineering’s Laboratory of Nanoscale Biology, has spent years working to enhance nanopore technology, which primarily involves a molecule like DNA through a tiny pore in a membrane to quantify an ionic current.

20 Jun 2023

Heat-Damaged DNA in Food Linked to Possible Genetic Risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

14 Jun 2023

Understanding Potential Mechanisms Underlying Genetic Variation in Older Trees

Older, long-lived trees are thought to contribute more to the creation and maintenance of genetic mutations than short-lived trees, according to research on the link between the growth rate of tropical trees and the frequency of genetic mutations they collect.

7 Jun 2023