Organelle News and Research

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Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

New Insight Into Cellular Waste Disposal Process

To prevent our body's cells from overflowing with garbage and to keep them healthy, the waste inside them is constantly being disposed of.

25 May 2023

Investigators Characterize and Name the Protein Domain that Governs Collagen Transport

Discovery of the MOTH domain offers insights into evolution. This is because both insects and vertebrates need collagen in their connective tissue.

23 May 2023

Proteomics Approach Identifies p62-Mediated Selective Autophagy of the Supramolecular Vault Complex

Our body functioning is delicately balanced between the synthesis and breakdown of various cellular components.

16 May 2023

Learning More About Stem Cells Advances Personalized Regenerative Medicine

Organelles, which are made up of various protein and RNA fragments inside of a cell, are crucial for maintaining homeostasis, controlling aging and development, and producing energy.

16 May 2023

Novel Technique Enables In Vivo Cross‐linking for Protein Complex Analysis

As the executor of life activities, proteins exert their specific biological functions through interactions such as forming protein complexes.

10 May 2023

Novel Tridimensional Anticancer Agents Have the Ability to Overcome Drug Resistance in Cancer Cells

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

3 Apr 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

How specialized plant “train tracks” can be used to feed the expanding population

A new study will examine the possibility that specialized plant “train tracks” that transport chemicals within cells could help in feeding the world’s expanding population.

From The University of Warwick 23 Mar 2023

Stem cells must take out the trash to protect against age-related diseases

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

22 Mar 2023

Perspectives on nucleolar DNA damage response in the fight against cancer

Cancer, which affects so many people each year, relies on proteins to proliferate throughout the body. Scientists are damaging the disease’s protein factories as part of a new tactic to combat the widespread disease.

20 Mar 2023

DZNE scientists discover major role of centrosome in neuronal migration

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.

16 Feb 2023

Versatile molecular toolbox expands the scope of gene regulation

Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.

15 Feb 2023

Figuring out how cells safeguard their genomes during replication

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome, a cell’s complete set of DNA, is most vulnerable while it is being duplicated before a cell divides.

26 Jan 2023

Discovery of a new cellular element crucial to sense of smell

Researchers at Umeå University have found an organelle, a previously unidentified cellular component, inside the neurons that are responsible for the ability to smell. The finding might have repercussions for future studies on COVID-19 symptoms like impaired smell sense.

5 Jan 2023

Conserved vacuolar sorting hub regulates autophagic flux in plants

A “hub and spoke” system allows plant cells to effectively coordinate cellular trafficking, especially for cellular recycling, also known as autophagy. Autophagosomes are specialized vesicles that capture hazardous molecules and transport them to the vacuole, where they are destroyed.

21 Oct 2022

Optogenetic control of mitochondria–lysosome contacts induce mitochondrial fission with spatiotemporal accuracy

Researchers from UC, the University of Illinois Urbana-Champaign, and the University at Buffalo demonstrated that light-activated proteins can help normalize dysfunction within cells.

8 Aug 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.