Organic chemistry News and Research

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Refreshers develop new DNA sequencing method

An international research team headed by Michal Hocek of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and Charles University and Ciara K. O'Sullivan of Universitat Rovira i Virgili (URV) in Spain have developed a novel method for labeling DNA, which in the future can be used for sequencing DNA by means of electrochemical detection.

18 May 2021

An efficient automated method for production of synthetic DNA

Chemically synthesized short DNA sequences are extremely important ingredients with countless uses in research laboratories, hospitals, and in industry, like in the method for identifying COVID-19.

13 May 2021

“Chemical nose” smells vital variations in unusual folding of DNA structures

Small variations in the structure of DNA have been related to breast cancer and other diseases, but they have been incredibly hard to find so far.

6 May 2021

Fluorescent chemical dye helps track specific motor protein within cells

A cell can stay alive only when it supplies all the required energy elements to its various organelles and these elements are formed in the Golgi apparatus.

8 Mar 2021

Researchers find large quantities of previously undetected PFAS

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) found large quantities of previously undetectable compounds from the family of chemicals known as PFAS in six watersheds on Cape Cod using a new method to quantify and identify PFAS compounds.

8 Mar 2021

Scientists discover how the 3D structure of eye-lens proteins is formed

The lens of the human eye gets its transparency and refractive power from the fact that certain proteins are densely packed in its cells.

11 Feb 2021

Effective, Controlled Turbulent Mixing for Flow Chemistry

The Uniqsis range of Glass Static Mixer (GSM) chip reactor blocks produce an efficient, turbulent mixed reagent stream for flow chemistry reactions that is not diffusion dependent.

From Uniqsis Ltd 18 Jan 2021

Study shows fluorescent protein molecules act as tiny antennas with optical properties

Scientists have revealed that fluorescent protein molecules serve as antennas with optical characteristics according to their spatial orientation.

4 Dec 2020

Chemists identify effective inhibitors to block the uptake of SARS-CoV-2

The cell membrane is impermeable to viruses: to get inside and infect a cell, they use a range of strategies to exploit the cellular and biochemical properties of the membranes.

23 Nov 2020

Researchers develop RNA catalyst that sheds light on evolution

Enzymes enable biochemical reactions that would otherwise not take place on their own. In nature, it is mostly proteins that function as enzymes.

29 Oct 2020

Innovative machine learning concepts can help develop new drugs

Tandem mass spectrometry is a powerful analytical tool used to characterize complex mixtures in drug discovery and other fields.

15 Oct 2020

DNA damage may occur far away from the point of incidence of radiation, research shows

Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers of Karlsruhe Institute of Technology (KIT) have demonstrated that DNA damage may also occur far away from the point of incidence of the radiation.

15 Sep 2020

FlowSyn continuous flow reactor helps to quickly evaluate critical reactions

Uniqsis reports how a FlowSyn™ continuous flow reactor installed at Adesis Inc. of New Castle, DE (USA) is assisting them in evaluating custom synthetic routes for compounds along with improving existing batch manufacturing processes.

From Uniqsis Ltd 3 Sep 2020

Understanding the structure of SARS-CoV-2 proteins may lead to novel drugs

COVID-19 is a disease caused by an RNA virus called SARS coronavirus 2 (SARS-CoV-2), that is, a virus that employs RNA to preserve its genetic data.

31 Jul 2020

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

Chinese researchers recently discovered a protein quality control mechanism called "reubiquitination".

9 Jul 2020

New method to synthesize cancer-fighting phytochemicals

Phytoalexins have attracted a great deal of interest because of their major role in plant health and their health-promoting effects in humans.

26 Jun 2020

New project to make better fluorescent tags turns into a method to kill tumors

A Rice University lab's project to make better fluorescent tags has turned into a method to kill tumors. Switching one atom in the tag does the trick.

12 Jun 2020

New method imitates how plants produce hormones

Plants produce the hormone jasmonic acid as a defense response when challenged. This is how they ensure that their predators no longer like the taste of their leaves.

1 Jun 2020

Using light to control the viability and mobility of individual cells

Photopharmacology is the study that examines the use of light to change the impact of drugs on and off. For the first time, researchers from Jena, Munich, and New York have successfully applied this technique to regulate a component of cells that was earlier believed to be inaccessible.

18 May 2020

Leap Forward In The Discovery And Development Of New Antibiotics

A powerful new insight, linked to recent studies, has provided a new understanding of Glycopeptide antibiotics biosynthesis that allows new GPAs to be made.

18 May 2020