Proliferation News and Research

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Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

The niche areas in which phenotypic screening continues to be advantageous over the targeted approach, and the recent advances in phenotypic screening technology that have increased their efficiency.

26 Jul 2024

Liver-on-Chips: Innovations, Applications, and Challenges in Drug Development

The development and application of liver-on-chips and the factors preventing its widespread use in drug discovery.

12 Jul 2024

UNC-Chapel Hill Study Reveals New Mechanism of Gene Regulation Beyond Histone Modification

University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation according to the paper, "Drosophila melanogaster Set8 and L(3)mbt function in gene expression independently of histone H4 lysine 20 methylation," published in Genes & Development.

11 Jul 2024

Are Advances in AI Technology Transforming Immunohistochemistry Analysis in Pathology?

The platforms and AI-based programs that are being used to analyze immunohistochemical markers and interpret the results.

3 Jul 2024

Unexpectedly Large Genomes Found in Mycena Mushroom Species

A study of multiple Mycena mushroom species reported in the journal Cell Genomics has found that they have unexpectedly large genomes.

1 Jul 2024

Study Highlights MSC-EVs Potential for Alleviating Lung Fibrosis

Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by fibroblast proliferation and extracellular matrix formation, causing structural damage and lung failure.

27 Jun 2024

Study Identifies Three Distinct Subtypes of Clear Cell Renal Cell Carcinoma Using Radiomics and Transcriptomics

Using transcriptomics and radiomics data clustering and its association with molecular characteristics, clinical pathologies, and prognosis to define intrinsic subtypes of ccRCC.

24 Jun 2024

Stem cell-based kidney chip revolutionizes disease modeling and research

An organ-on-chip system containing a kidney glomerulus using human-induced pluripotent stem cells and an ultrathin membrane.

17 Jun 2024

Mitochondria Influence the Ability of Adult Cardiac Cells to Multiply

Whether forcing adult cardiomyocytes to reverse from the oxidative phosphorylation phenotype to the glycolysis phenotype would also restore their mitotic ability.

13 Jun 2024

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

12 Jun 2024

Critical NPC Protein Nup358 Linked to Myeloid Disorders

Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell survival, proliferation, and differentiation.

6 Jun 2024

Stem Cell Factor Levels Show Promise in Predicting Successful IVF for Endometriosis

The ability of serum levels of stem cell factor to indicate the quality of oocyte and blastocyst development.

4 Jun 2024

How Immune Cells Decode Cancer's Turbocharged State

When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies.

22 May 2024

Proliferation News and Research

Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

Liver-on-Chips: Innovations, Applications, and Challenges in Drug Development

UNC-Chapel Hill Study Reveals New Mechanism of Gene Regulation Beyond Histone Modification

Are Advances in AI Technology Transforming Immunohistochemistry Analysis in Pathology?

Unexpectedly Large Genomes Found in Mycena Mushroom Species

Study Highlights MSC-EVs Potential for Alleviating Lung Fibrosis

Study Identifies Three Distinct Subtypes of Clear Cell Renal Cell Carcinoma Using Radiomics and Transcriptomics

Stem cell-based kidney chip revolutionizes disease modeling and research

Mitochondria Influence the Ability of Adult Cardiac Cells to Multiply

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Critical NPC Protein Nup358 Linked to Myeloid Disorders

Stem Cell Factor Levels Show Promise in Predicting Successful IVF for Endometriosis

How Immune Cells Decode Cancer's Turbocharged State

Mesenchymal stem cell-derived exosomes carrying vincristine sulfate are effective in killing cancer stem cells

Researchers Uncover More Genes Linked to Clonal Hematopoiesis

Fruit Fly Model Unveils Hidden Mechanisms of Organ Development

St. Jude Scientists Reveal Role of Non-Coding DNA Variants in Childhood Leukemia

First Comprehensive Map of Protein Movement in Yeast Cell Cycle Revealed

Unveiling Mechanisms to Block Tau Aggregation

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

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