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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

New sample pre-treatment method enables efficient protein recovery

The cells’ proteins contain a huge world of information that, when unlocked, can shed light on the causes of many fundamental biological occurrences. To observe the properties of individual cells at the protein level, a single-cell analysis method known as “single-cell proteomics” is used.

8 Aug 2022

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Nature’s storage solution originally emerged in ancient microbes living on Earth around one and two billion years ago, according to researchers at the Center for Genomic Regulation (CRG).

10 Jun 2022

Researchers use urinary proteomics to detect abnormalities inside the body

Dr Jun Qin, a proteomics expert from the State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, and Dr Zhongde Zhang from The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, worked in the front line of compacting COVID-19 disease.

23 Mar 2022

Placenta plays an active role in the delivery of maternal vitamin D to the fetus

Scientists have shed new light on the role of the placenta in managing the relationships between maternal vitamin D and fetal development, according to a study published today in eLife.

9 Mar 2022

Researchers show how hotspot maps can detect structures contributing to compounds’ selectivity

The quantity of structural data available on protein drug targets keeps growing.

4 Mar 2022

Researchers identify cellular mechanism that protects proteins from breaking down

Plants are tied to one location and need to adjust to their environment, including adverse conditions. Adaptive responses include synthesizing new proteins and breaking down those that are no longer needed.

11 Feb 2022

Researchers take a deep dive in understanding “dark proteome”

Researchers predicted that there would be approximately 20,000 protein-coding genes when the human genome sequence was revealed two decades ago.

31 Jan 2022

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

NeoCura and PhoreMost today announced an oncology drug discovery research collaboration.

From PhoreMost 11 Jan 2022

Study identifies two proteins as novel markers of aggressive prostate cancer

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome.

23 Dec 2021

Revealing a Cell's Components through Artificial Intelligence

We speak to Professor Trey Ideker and Yue Qin about their latest in cell biology and how artificial intelligence could be used to discover new components within cells.

From UC San Diego 23 Dec 2021

Researchers identify production mechanism of light-sensitive protein of photoreceptors

Every 6 minutes someone is told they're going blind. One of the major causes of human blindness is a disease called Retinitis Pigmentosa (RP), which causes progressive degeneration of the retina and vision loss.

20 Dec 2021

Massive study on plasma proteome enhances understanding of human diseases

Recent research by investigators from deCODE genetics revealed how proteins drastically enhance the understanding of human diseases.

7 Dec 2021

Study finds amphipathic peptide that safely opens endosomal membrane

The cell plasma membrane and the derived endosomal membranes are both greasy barriers that prevent the inflow of water-soluble macromolecules like nucleic acids and proteins into cells.

2 Dec 2021

Diet has a much stronger impact on the inner workings of cells than drugs

A study comparing the impact of diet versus drugs on the inner workings of our cells has found nutrition has a much stronger impact.

17 Nov 2021

Novel technique enhances the predictability of protein manufacturing

Researchers from VIB and Ghent University devised a new technique to analyze the secretability of hundreds of thousands of protein sequences at once.

10 Nov 2021

Biognosys Launches Next-Generation Blood Biomarker Discovery Solution

Biognosys today announces the launch of its next-generation blood biomarker discovery solution, which will be offered as a contract research service.

From Biognosys 10 Nov 2021

SCIEX and Evosep will collaborate to provide robust, high-throughput proteomics workflows

Today, SCIEX and Evosep announce an agreement to co-market products together to improve robust, high-throughput proteomics workflows for precision medicine.

From SCIEX 5 Nov 2021

Simultaneously Measuring 7,000 Proteins: Groundbreaking Proteomics from SomaLogic

In this interview, we speak to Roy Smythe, CEO of SomaLogic, about their groundbreaking proteomics technology that can simultaneously measure 7,000 proteins.

From SomaLogic 4 Nov 2021

Scientists develop new tool to identify neuronal proteins in animal models

Scientists, for the first time, developed a successful method for pinpointing proteins within different kinds of neurons in the brain of a living animal.

16 Aug 2021

Already characterized active substances exhibit unexpected effects

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021