Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Computational methods can help design protein-based vaccines

Vaccines are regarded as an effective intervention to stop the spread of infectious diseases. They produce antibodies by activating the immune system.

18 May 2020

Study shows the dual role of amyloid proteins in Bacillus physiology

When Bacillus subtilis cells are deprived of an amyloid protein, they show a range of cytological dysfunctions and anomalies that cause their premature death.

18 May 2020

Discovering a Protein that Controls Brain-Blood Vessel Development

AZoLifeSciences speaks to Professor Long Nam Nguyen about his research which led to the discovery of a protein that controls brain-blood vessel development.

From National University of Singapore (NUS) 15 May 2020

Researchers identify missing component of innate immune signaling

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans.

14 May 2020

Study shows how plant viral protein disrupts cell division to promote its own propagation

Viruses are ever-present pathogens that lead to severe infectious diseases in humans as well as in agricultural crops.

14 May 2020

Study shows protein shredder also regulates fat metabolism indirectly

A protein shredder takes place in the cell membranes of brain cells. A new study has demonstrated that this protein shredder also controls fat metabolism.

11 May 2020

MSC‐induced Treg population can yield abundant replacement for naturally occurring T-cells

A new study released today in STEM CELLS suggests for the first time that regulatory T-cells (Treg) induced by mesenchymal stromal cells can yield an abundant replacement for naturally occurring T-cells, which are vital in protecting the body from infection.

30 Apr 2020

Certain proteins in bones could help estimate the time of death

When a corpse is discovered, one of the foremost things a forensic pathologist would do is to predict the time of death.

30 Apr 2020

Hyperosmotic stress induces phase separation of the proteasomes

Cellular proteostasis is regulated by a crucial proteolytic machine called proteasome via selective degradation of ubiquitylated proteins.

29 Apr 2020

Study shows how DNA mimic protein helps phages to attack their victims

A research team from the Severinov Laboratory at Skoltech, together with their collaborators from Israel and Switzerland, has analyzed a bacterial BREX defense mechanism that was poorly studied to date.

29 Apr 2020

Novel protein sensor controls the pathway of fat and sugar conversion in humans

Researchers in Pennsylvania and Texas have discovered a novel protein sensor that limits the amounts of fat and sugar that are converted into energy by human cells, during the starvation periods.

27 Apr 2020

Developing novel compounds that inhibit SARS-CoV-2 main protease

A research team from China has now created two novel compounds that block the SARS-CoV-2 main protease (Mpro).

23 Apr 2020

Preventing viral infections by protein shell misassembly

A study published recently in eLife reports new understanding of conditions that govern self-assembly in the protective shell of viruses.

23 Apr 2020

Mitochondrial protein contributes to degenerative diseases

Scientists and their collaborators from Duke-NUS Medical School (Duke NUS) have recently identified a novel small protein in mitochondria, which is essential for energy production.

17 Apr 2020

New method images proteins in 3D with nanoscale resolution

A research team, which also included scientists from the National Synchrotron Light Source II (NSLS-II), has reported a novel method for imaging proteins in three dimensions (3D) with nanoscale resolution.

16 Apr 2020

Metals can affect the formation of harmful misfolded peptide clusters in various diseases

Revealing the interactions between metal ions and peptides in the body could help develop enhanced treatments for Alzheimer’s diabetes, and other diseases.

14 Apr 2020