Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.
Multiple changes in brain cells during the first month of embryonic development may contribute to schizophrenia later in life, according to a new study by Weill Cornell Medicine investigators.
According to a study, grown-ups with certain genetic causes of mental health and other brain disorders had substantially increased rates of chronic disease.
New research published in the Proceedings of the National Academy of Sciences shows that examining genetic mutations in individuals with severe schizophrenia can improve the ability to detect disease-associated rare genetic variants.
Columbia University researchers have determined that individuals who suffer from the most severe form of schizophrenia have a significantly higher number of rare mutations than more typical forms of the illness.
In 2019 University of California San Diego researchers discovered the area of the brain where "value decisions" are made.
Earlier studies suggest that autism spectrum disorder (ASD) might be partly due to differences in the gut microbiota composition.
A genetic predisposition for depression combined with exposure to high-particulate-matter air pollution greatly elevates the risk that healthy people will experience depression, according to a first-of-its-kind study published today in the Proceedings of the National Academies of Sciences from neuroscientists at the Lieber Institute for Brain Development, on the Johns Hopkins Medical Campus, and Peking University in Beijing, China.
Living in cities has been highlighted as an environmental risk factor for schizophrenia and, to a lesser extent, other mental health conditions. However, few studies have explored genetic effects on the choice of residence.
Mushrooms have been making headlines due to their many health advantages. Not only do they lower one's risk of cancer and premature death, but new research led by Penn State College of Medicine also reveals that these superfoods may benefit a person's mental health.
Human DNA has a close resemblance to that of the chimpanzee, which in evolutionary terms is the closest living relative of humans.
A group of scientists identified that a prevailing drug for treating constipation might boost an individual’s capability to think with better clarity.
Scientists went through the records of more than 8,000 schizophrenia patients and identified a tool used for assessing an individual’s genetic risk for a disease.
Have you ever met someone you instantly liked, or at other times, someone who you knew immediately that you did not want to be friends with, although you did not know why?
Chronic stress is a well-known cause for mental health disorders. New research has moved a step forward in understanding how glucocorticoid hormones ('stress hormones') act upon the brain and what their function is.
Scientists have found that when brain cells develop, they may find various ways to link with each other based on sex.
A research team revealed that neurotransmitter release in the brain is impaired in patients with schizophrenia who possess a rare, single-gene mutation.
Scientists discovered 22 lipids in the blood plasma of schizophrenia patients that were linked to slower symptom improvement over time.
For the first time, scientists have linked distinct patterns of genetic mutations with OCD in humans using genome-wide analysis.
When we think of the brain, we think of neurons. But much of the brain is made of non-neuronal cells called glial cells, which help regulate brain development and function.
Researchers have demonstrated how cell “batteries” play a significant role in whether patients with the chromosomal deletion syndrome acquire schizophrenia.