Sepsis News and Research

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Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Discovery of chiral evasion could lead to more resilient inhibitors, better drug designs

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial infection that has become resistant to most of the antibiotics used to treat regular staph infections.

18 Feb 2022

One-time infusion of stem cells from bone marrow improves sepsis survival in mice

A one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis, shows a study published today in eLife.

16 Feb 2022

Scientists discover “resistance gene” in harmful E. coli bacteria

Researchers have discovered a gene that makes E. coli bacteria resistant to antibiotics, effectively leading to better treatment for people across the globe.

20 Jan 2022

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022

Driving up the immune response at tumor site may help boost immunotherapy

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

15 Dec 2021

Immune cells utilize the body’s fat stores to combat infection, says study

A recent study carried out by the University of East Anglia and Quadram Institute shows how immune cells utilize the body’s fat stores to combat infection.

9 Dec 2021

Genetic markers linked to increased lipopolysaccharide level in blood discovered

Lipopolysaccharide (LPS), a bacterial component, is a toxin and its increased concentrations in the blood induce sepsis.

29 Oct 2021

Scientists develop a technique for reconstructing whole genomes on a personal computer

Scientists at the Massachusetts Institute of Technology and the Institut Pasteur in France have developed a technique for reconstructing whole genomes, including the human genome, on a personal computer.

From Massachusetts Institute of Technology (MIT) 15 Sep 2021

Researchers discover underlying metabolic changes that may be pivotal in severe COVID-19

COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death.

7 Sep 2021

Study analyzes the health benefits of time-restricted eating

Time-restricted eating (TRE) is a dietary regimen in which eating is restricted to particular hours. It has received great attention in weight-loss circles.

19 Aug 2021

INRS professor receives $700,000 for research on bacteria of the nasopharynx

Professor Frédéric Veyrier of the Institut national de la recherche scientifique (INRS) has received $711,450 from the Canadian Institutes of Health Research (CIHR) for a project on bacteria of the nasopharynx, including Neisseria.

16 Apr 2021

New label-free immune profiling assay to assess rapidly changing host immune response

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a new label-free immune profiling assay that profiles the rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves, which can often be at low levels within a host.

26 Mar 2021

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.

15 Feb 2021

Noncoding RNA plays key role in sepsis, regulates inflammatory gene expression

Sepsis can result when the body’s immune response to a specific infection gets out of control.

From University of California Santa Cruz 2 Feb 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

New class of protein materials can influence cell signaling

A new study has revealed that a novel class of protein material that communicates with living cells without being absorbed by them can affect cell signaling. The protein material does this by attaching and sequestering cell surface receptors.

7 Jan 2021

Sugar-binding protein could serve as a useful biomarker for patients at risk of sepsis

According to a research team headed by the University of Connecticut Health, a sugar-binding protein could drive terrible inflammation and worsen sepsis—a disease that kills over 270,000 individuals per year in the United States alone.

5 Jan 2021

New study targets small proteins in Salmonella to combat the pathogen

Salmonella is a type of bacteria that causes food poisoning upon infection, with acute diarrhea.

17 Dec 2020

Adipose tissue plays key role in the aggravation of COVID-19

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

23 Nov 2020

Gaining new insights into bacterial pneumonia

Jacqueline Kimmey speaks to AZoLifeSciences about her research into bacterial pneumonia and the genes that drive its spread from the lungs into the blood.

From University of California Santa Cruz 23 Nov 2020