Splicing News and Research

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Revealing the functional significance of DDX41 in great detail

The DDX41 gene encodes the nuclear enzyme DEAD-box-type RNA helicase. Hematopoietic malignancies are caused by DDX41 mutations. However, the mechanism behind the development of this malignancy remains unknown.

21 Nov 2022

The genetic mechanisms that induce protein decline in modern maize

The wild ancestor of maize, teosinte, contains three times as much seed protein as the majority of cultivars of maize today. The mechanisms causing the declining seed protein content in maize hybrids and inbred lines were identified by researchers at the Chinese Academy of Sciences Headquarters.

17 Nov 2022

New tool advances potential means to deliver gene therapy

Researchers from Johns Hopkins Medicine claim to have successfully “slid” genetic instructions into a cell and produced essential proteins that were lacking from those cells using a cell’s normal process for creating proteins.

1 Nov 2022

Researchers discover the gene essential for the growth of photoreceptors

Srrm3 is a master regulator gene essential for the growth of photoreceptors, cells in the rear of the retina that catch and process light and transmit signals to the brain that allow vision, according to research, from the Centre for Genomic Regulation (CRG) in Barcelona.

14 Jul 2022

Researchers discover how the protein content of centrosomes may vary on cell type

The centrosome is the organelle that organizes the cytoskeleton during cell division, which is an important role in species ranging from yeast to humans. Due to its broad functions, scientists previously considered that the centrosome was quite similar in all cells.

17 Jun 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Rootstocks aid in breeding new tomato varieties that can endure heat and drought

Today's current varieties of tomatoes – ones grown in gardens and available in produce sections and farmers' markets – are a bit spoiled.

24 May 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

New and unconventional nuclear function for oncogenic microRNA discovered

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

Scientists discover families of proteins that could predict organ transplant rejection

Northwestern University scientists have discovered families of proteins in the body that could potentially predict which patients may reject a new organ transplant, helping inform decisions about care.

28 Jan 2022

Researchers discover a gene variant that protects against severe COVID-19 infection

An international metastudy led by researchers at Karolinska Institute in Sweden has identified a specific gene variant that protects against severe COVID-19 infection.

17 Jan 2022

Scientists shed light on mechanisms responsible for maturation of the splicing machinery

Alternative Splicing is an extraordinarily complex process that requires the coordinated action of multiple proteins, each specialized in very specific functions. These proteins are assembled and matured, forming a kind of consortium of proteins that perform these gene reading functions.

31 Dec 2021

Splicing News and Research

Revealing the functional significance of DDX41 in great detail

The genetic mechanisms that induce protein decline in modern maize

New tool advances potential means to deliver gene therapy

Researchers discover the gene essential for the growth of photoreceptors

Researchers discover how the protein content of centrosomes may vary on cell type

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

Rootstocks aid in breeding new tomato varieties that can endure heat and drought

Study shows how nanotechnology may help for structural research of RNA molecules

Novel molecular pathway shared by ALS and frontotemporal dementia identified

New and unconventional nuclear function for oncogenic microRNA discovered

Scientists discover families of proteins that could predict organ transplant rejection

Researchers discover a gene variant that protects against severe COVID-19 infection

Scientists shed light on mechanisms responsible for maturation of the splicing machinery

Revealing a Cell's Components through Artificial Intelligence

De Novo Mutations may Play a Role in Male Infertility

Study reveals mechanisms promoting overall glioma tumor growth

Study finds the link between circular RNA and alternative splicing in gastric cancer

Researchers identify a novel pathomechanism leading to Usher syndrome

'Enabler cells' in tumors could promote cancer metastasis

Researchers systematically analyze alternative splicing in the family of glutamate receptors

Genome Editing Has A New Code

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

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