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T-cells are a critical component of the adaptive immune system and are indispensable in protecting humans from pathogenic infections.

Scientists show how skin T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

15 Oct 2021

Diagnostic value of SARS-CoV-2 specific T cell immune responses may be limited

Can T-cell tests be used to determine whether people have had COVID-19? Scientists at Uppsala University and Karolinska Institutet have jointly analysed this issue under the aegis of the COMMUNITY study at Danderyd Hospital. Their study is published in the scientific journal PLOS ONE.

5 Oct 2021

CSHLP releases new book on the arsenal of memory T-cells

Cold Spring Harbor Laboratory Press (CSHLP) announced the release of T-Cell Memory, available on its website in hardcover and eBook formats.

21 Sep 2021

Gut bacteria may play a key role in neurological damage of premature infants

Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role.

6 Sep 2021

Researchers develop heat-controllable CAR T cells to kill tumors and prevent relapse

A team of researchers led by bioengineers at the Georgia Institute of Technology is expanding the precision and ability of a revolutionary immunotherapy that is already transforming oncology. CAR T-Cell therapy has been hailed by patients, clinical-researchers, investors, and the media as a viable cure for some cancers.

19 Aug 2021

Study assesses the effectiveness of T-cell immune response to different SARS-CoV-2 variants

New mutations of the SARS-CoV-2 virus have been emerging continuously, enabling a more potent spread of the virus and allowing it to evade antibodies.

16 Aug 2021

New formulation to administer antibodies for choroidal neovascularization therapy

Scientists have created a new formulation based on regulatory T-cell exosomes (rEXS) to administer vascular endothelial growth factor (VEGF) antibodies.

28 Jul 2021

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Researchers from the University of Oxford suggest that adenovirus vaccine vectors may create strong long-term immune system responses.

19 Jul 2021

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

Computer scientist Lydia Kavraki of Rice University's Brown School of Engineering has won a prestigious National Institutes of Health U01 grant to develop a new approach to model and analyze protein-ligand interactions in cancer research.

8 Jun 2021

Newly identified protein helps tumors evade the immune system

Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

3 Jun 2021

Immune system’s killer T cells make mistakes in distinguishing healthy from infectious cell

When it comes to differentiating between a healthy cell and an infectious cell that has to be killed, the immune system’s killer T cells might make mistakes.

27 May 2021

Study shows how T cells detect dangerous invaders in the human body

T-cells are known to play a crucial role in the human immune system.

7 May 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Researchers use mathematical modeling to explain CAR T-cell therapy dynamics

Chimeric antigen receptor T-cell therapy, or CAR T, is a relatively new type of therapy approved to treat several types of aggressive B cell leukemias and lymphomas.

26 Mar 2021

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread.

25 Mar 2021

Study shows SARS-CoV-2 antibodies wane at different rates

Researchers from Duke-NUS Medical School, the National Centre for Infectious Diseases (NCID), and the Agency for Science, Technology and Research (A*STAR) Infectious Diseases Labs have discovered that antibodies against SARS-CoV-2 decline at different speeds, and these antibodies last for only a few days in some people but remain for many years in other individuals.

24 Mar 2021

Study sheds light on how T cells specialize to combat pathogens

Scientists from the University of Basel have gained insights into the specialization of T cells.

11 Mar 2021

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

9 Mar 2021

Engineered safety switch reduces CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

5 Mar 2021

Scientists map previously unknown metabolic pathways to produce memory T cell

Immunologists have plotted a previously unfamiliar biological pathway through which the immune system produces T cells that destroy viruses.

26 Feb 2021