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Structural Insights Unmask Novel Adaptations and Functions of Human LINE-1 ORF2

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

20 Dec 2023

Decoding Zebrafish Development: A Comprehensive Gene Expression Atlas

Scientists from the National Institutes of Health have released a comprehensive guide to the development of zebrafish, outlining the gene expression patterns activated in almost every cell type during the initial five days of growth.

19 Dec 2023

Scientists Crack the Code for Artificial DNA

The genetic code is composed of just four letters representing the four nucleotides, which are the fundamental building blocks of DNA.

14 Dec 2023

Tailored Nanoparticles Deliver siRNA to Reduce Neuroinflammation in Alzheimer's Disease Models

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells.

11 Dec 2023

Unraveling Oxygen's Impact on Protein Dynamics

Understanding the adverse effects of insufficient oxygen becomes apparent with the simple act of holding ones breath for too long.

11 Dec 2023

The Extraordinary Genetic Memory System of Dormant Bacterial Spores

A recent investigation led by Professor Sigal Ben Yehuda and her team at Hebrew University has brought to light a fascinating aspect of bacterial dormancy.

28 Nov 2023

Nutrient Derived From Meat and Dairy Enhances Cancer Killing Ability of Immune Cells

Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study by researchers from the University of Chicago.

27 Nov 2023

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology.

22 Nov 2023

Scientists Discover New Class of Molecular Glue Degraders for Cancer Therapy

Cells contain molecular machinery that targets and disposes of unwanted proteins to maintain homeostasis.

17 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

SPT5 Identified as a Potential Target Protein for Treatment of MYC-Dependent Cancers

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins - with clear consequences for the tumor.

8 Nov 2023

Unlocking the Secrets of Bacterial Transcription

Bacterial transcription serves as an assembly line for duplicating genetic directives from double-stranded DNA into RNA molecules.

7 Nov 2023

New LoCKAmp Device Delivers Lab-Quality COVID Test Results in Just 3 Minutes

A virus diagnosis device that gives lab-quality results within just three minutes has been invented by engineers at the University of Bath, who describe it as the 'world's fastest Covid test'.

3 Nov 2023

The Dominant Phage-Resistant LAB in Long-Term Kimchi Fermentation

Scientists from the World Institute of Kimchi have successfully extracted lactic acid bacteria (LAB) strains that exhibit remarkable phage resistance.

2 Nov 2023

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

The Exclusome, A New Mammalian "Container"

We speak to Dr. Ruth Kroschewski about new research that details the existence of an 'exclusome', a cytoplasmic container that appears to explain where extra-chromosomal DNA goes once it is in a cell.

24 Oct 2023

DNA-Origami Nanoengine Performing Pulsing Movements

An international team of scientists has just invented a revolutionary form of DNA nano-engine.

20 Oct 2023

DNA Methylation Enables Plants Adapt in a Warm World

Plants increasingly need to adapt quickly to preserve their existence as global warming continues to reshape ecosystems.

13 Oct 2023

DNA Aptamer Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

12 Oct 2023

Interdisciplinary Research at Colorado State Showcases Key Cell Activity in Real Time

Researchers at Colorado State University have developed a new imagining technique that shows key cellular interactions over time and space in a way that was not previously possible.

11 Oct 2023