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New biomedical research tool may help advance molecular diagnostics and drug discovery

A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery.

30 Jun 2022

Research shows the molecular pathways for trichrome formation and cannabis production

Many compounds known as cannabinoids are found in cannabis, a plant that is receiving more and more attention for its extensive medical potential.

27 Jun 2022

Scientists reveal how autism-linked genetic mutation disrupts neural development using mini-brains

In a study published May 02, 2022 in Nature Communications, scientists at University of California San Diego School of Medicine used human brain organoids to reveal how a genetic mutation associated with a profound form of autism disrupts neural development.

From UC San Diego 3 May 2022

Study identifies novel targets for treating sorafenib-resistant hepatocellular carcinoma

Research headed by Professor Xiujun Cai used the CRISPR/cas9 system to screen the entire genome of hepatocellular carcinoma cells (HepG2) under sorafenib treatment.

25 Apr 2022

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Scientists identify factors that regulate the development of brain cells in a specific order

Researchers have identified the complete series of 10 factors that regulate the development of brain cell types in the visual system of fruit flies-; including in what order these neurons develop.

From New York University (NYU) 7 Apr 2022

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern.

6 Apr 2022

New map tracks cellular trajectories across mouse embryogenensis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

15 Mar 2022

Research shows DLX2 protein regenerate astrocytes into neural stem-like cells

A single protein may turn adult brain cells termed astrocytes into stem-like cells that create neurons and other cell types, according to UT Southwestern researchers.

9 Mar 2022

Study identifies the role of three key molecules in the immune defense against porcine reproductive and respiratory syndrome virus

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is one of the most deadly diseases in the swine industry.

4 Mar 2022

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Although gene mutations can result in drug resistance, scientists in the Perelman School of Medicine at the University of Pennsylvania have found a vital, non-genetic version that could also boost resistance to targeted treatment in T cell leukemia, which is a kind of blood cell cancer.

3 Mar 2022

UH researcher secures $2 million to develop drugs for formerly undruggable cancer targets

With a $2 million recruitment grant from the Cancer Prevention and Research Institute of Texas, a University of Houston researcher is setting up a lab to develop drugs that will work on traditionally undruggable targets in cancer.

3 Mar 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

Dresden researchers explain how liquid-like protein droplets read DNA regions

A single cell forms the basis of life. As an organism grows, dividing cells specialize to produce the many tissues and organs that make up the adult body.

From The Max Planck Institute 14 Feb 2022

Study shows how root symbiosis with fungi is driven by the plant’s phosphate status

Phosphorus is one of the most important nutrients for plants. Among other functions, it is needed to create substances for the plant’s immune system, for the healthy development of seeds and for root growth.

9 Feb 2022

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

Researchers make new advances in connecting the evolution of pregnancy and cancer metastasis

Researchers from UConn Heath and Yale University have made new advances connecting the evolution of pregnancy and cancer metastasis.

8 Feb 2022

Cell communication determines the specialization of individual cells during development, study shows

In just a few weeks a completely new organism develops from a fertilized egg cell. The real miracle is that a bunch of identical stem cells turns into completely different, specialized cell types.

From The Max Planck Institute 9 Nov 2021

Researchers reveal the dual function of a zinc finger protein

Human genome mapping was followed by rapid scientific advancements that showed the astonishingly complex world of genetics.

29 Oct 2021

Researchers identify a gene that could help improve flavor and shelf-life of tomatoes

Buying tomatoes and other fruits in the grocery store is always a gamble because, however good they look, they are often firm but lack flavor.

26 Oct 2021