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Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

25 Mar 2021

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread.

From National Cancer Institute (NCI) 25 Mar 2021

Specific enzyme can delay the growth and spread of neck and head carcinomas

Scientists were able to considerably delay the growth and proliferation of tumors in mice and improve the effectiveness of immunotherapy.

24 Mar 2021

Stem cell therapy could help restore debilitating muscle loss that happens with age

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

24 Mar 2021

Bacteria residing within tumor cells may boost cancer immunotherapy

Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. In a new study published in Nature, researchers at the Weizmann Institute of Science and their collaborators have discovered that the immune system "sees" these bacteria and shown they can be harnessed to provoke an immune reaction against the tumor.

23 Mar 2021

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Oncotarget published "Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells" which reported that although the molecular mechanism behind the antitumor properties of NSAIDs has been largely attributed to inhibition of cyclooxygenases , several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.

23 Mar 2021

Low representation of minority groups in genomic databases may impact therapy selection

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

22 Mar 2021

Study advances CAR T cell therapy targeted at cancer

Cancer immunotherapy involves the activation of cells in the patient’s own immune system to fight tumor cells.

19 Mar 2021

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

A study headed by UCM reports that polymorphisms in gene TGFB1 and low plasma levels of protein TGFB1 serve as biomarkers for the gastric adenocarcinoma prognosis.

19 Mar 2021

New machine learning method detects the pH of a cell to identify whether it is cancerous

Cancerous cells differ from healthy cells in various significant ways. This helps identify them as harmful.

17 Mar 2021

ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

Study reveals mechanisms behind the activation of MRN complex

Researchers from the Tokyo Institute of Technology have revealed mechanisms behind the stimulation of the MRN complex—the DNA scissors of the cells.

11 Mar 2021

Adhesion strength and contractility enable metastatic cancer cells to display adurotactic behavior

Bioengineers at the University of California San Diego and San Diego State University have discovered a key feature that allows cancer cells to break from typical cell behavior and migrate away from the stiffer tissue in a tumor, shedding light on the process of metastasis and offering possible new targets for cancer therapies.

From UC San Diego 10 Mar 2021

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

9 Mar 2021

Tumor News and Research

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Specific enzyme can delay the growth and spread of neck and head carcinomas

Stem cell therapy could help restore debilitating muscle loss that happens with age

Bacteria residing within tumor cells may boost cancer immunotherapy

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Low representation of minority groups in genomic databases may impact therapy selection

Study advances CAR T cell therapy targeted at cancer

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

New machine learning method detects the pH of a cell to identify whether it is cancerous

ADAR1 protein offers a potential therapeutic target for cancer

Study reveals mechanisms behind the activation of MRN complex

Adhesion strength and contractility enable metastatic cancer cells to display adurotactic behavior

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Promising drug targets identified for aggressive forms of cancers

New computational tool reveals the function and regulation of human genes

New technique reveals the tricks that cancer cells use to avoid immunotherapies

Scientists map previously unknown metabolic pathways to produce memory T cell

Study reveals new functions of ENDOU enzymes

Compounds from marine-derived fungus may protect cells from paraquat

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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