Tumorigenesis is the process involved in the production of a new tumor or tumors.
Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.
A new cause of severe childhood brain cancer has been discovered by scientists.
Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.
A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.
Researchers examined tumor cells that were resistant to the original treatment and identified molecular targets for therapies that could evade breast cancer recurrence.
Researchers have found that a protein named after the mythical land of youth in Irish folklore is efficient at reversing skeletal muscle cells aging.
Scientists demonstrated that normal human fibroblast cells can be converted to specific cancer cells through factors that are identified in actual human patients.
For decades, physicians and dieticians have urged people to limit their intake of high fat foods, citing links to poor health outcomes and some of the leading causes of death in the U.S., such as diabetes, heart disease and cancer.
A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge to the understanding of human complex traits and diseases.
Every eukaryotic organism contains the so-called transposons, which are abundant DNA-elements.
Volume 11, Issue 28 of Oncotarget features "Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice" by Xu et, al. which reported that the authors examined whether the TSGs Rb1, Trp53, Pten, and Men1 have cooperative effects in suppressing neuroendocrine tumors in mice.
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
Worldwide, cancer is the second leading cause of death - in 2018 alone, it claimed approximately 9.6 million lives, or one in six deaths.
Chemical lesions in the genetic material DNA can have catastrophic consequences for cells, and even for the organism concerned.
Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver gene.
A team of researchers has reported a article relating to human pluripotent stem cell-derived cardiomyocytes in the modeling and repair of heart disease.
The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.
Researchers from the German Cancer Research Center, Cambridge, and Edinburgh have been analyzing the evolution of tumors after chemical damage.
Canadian researchers have made a major breakthrough in the analysis of telomerase, a crucial enzyme involved in cancer and aging.
Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.