Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.
Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.
In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say.
AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.
Scientists at the La Jolla Institute for Immunology have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases.
A new way of using genetics to diagnose diabetes could pave the way for better diagnosis and treatment in Indians, new research has concluded.
A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside.
A study has uncovered how variations in a non-protein coding 'dark matter' region of the genome could make patients susceptible to complex autoimmune diseases.
Scientists have developed a technique to assess the impact of particular drugs in pancreatic tissues by using an advanced single-cell RNA sequencing approach.
The loss of insulin-secreting beta cells leads to type 1 diabetes. Islet cell transplantation has the potential to cure diabetes, but donors are rare.
The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer.
Researchers have found that immune T cells exhibit a range of responsiveness. This finding could offer insights into how the immune system of humans responds to infections and cancer, and what goes wrong in immune diseases.
At St. Jude Children’s Research Hospital, researchers have generated a database that detects gene-regulatory mechanisms in immune cells that promote Type 1 diabetes.
According to a new study performed by the University of Wisconsin-Madison, deleting a gene from insulin-producing cells prevents the development of Type 1 diabetes in mice, by sparing the cells from being attacked by their own immune system.
Researchers have discovered that pancreatic cells, producing lipids, can create their own autoimmune ending. This article looks at how this is possible.