Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.
According to researchers, genetically modified stem cells may also open the door to novel regenerative medicine therapies for conditions including Type 1 diabetes.
Throughout a person’s life, many stimuli can turn on and off many of the genes, resulting in the variances that distinguish people.
In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).
Scripps Researchers have found that looking at a certain type of immune cell in the blood can help pinpoint those who are most vulnerable to acquiring type 1 diabetes, a fatal autoimmune disease
The body's blood glucose level needs to be maintained in a relatively narrow range. It cannot be too high, as it can lead to diabetes, and it cannot be too low because it can cause fainting or even death.
A gene expression signature that has the potential to forecast the advance of type 1 diabetes has been determined by scientists from Turku Bioscience Centre and InFLAMES Flagship at the University of Turku in Finland.
Details of how the gut microbiota changes during the first three months of life will be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April).
A team of scientists from the Van Andel Institute and the Max Planck Institute for Immunobiology and Epigenetics uncovered two unique subtypes of insulin-producing beta cells, or ß cells, each having important traits that could potentially be used to better understand and treat Type 1 and Type 2 diabetes.
An artificial pancreas originally developed at the University of Virginia Center for Diabetes Technology improves blood sugar control in children ages 2 to 6 with type 1 diabetes, according to a new study.
Published in JAMA, a University of Minnesota led study shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes (T1D).
A massive clinical study on an approved psoriasis drug is now underway. The drug will be tested on people who have just been diagnosed with type 1 diabetes. The drug, according to the theory, could preserve the patient’s remaining insulin production.
Insulin injections to treat Type 1 diabetes could become a thing of the past, but finding the cure faces many challenges.
Nearly ten years ago, a graduate student at UO Jennifer Hampton Hill stumbled upon something fortunate: a peptide produced by gut bacteria that prompted the division of cells that make insulin.
Can the SARS-CoV-2 vaccine reactivate previously suppressed antibody responses and pave the way for a unified coronavirus vaccine?
Research studying the autoimmune response, in which the immune system kills the insulin-producing pancreatic islet beta cells, is a common topic of type 1 diabetes research.
Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.
A new study performed has offered better knowledge about how genetic factors tend to impact the immune response of the body in type 1 diabetes.
Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.
New advancements in the transplantation of stem cell-derived insulin-producing beta cells to cure type 1 diabetes have created substantial curiosity.
Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.